A5004870667- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Therapy and Dosimetry
- Meningioma and schwannoma management
- Head and Neck Cancer Studies
- Brain Metastases and Treatment
- Advanced Neuroimaging Techniques and Applications
- Advances in Oncology and Radiotherapy
- Lung Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- NMR spectroscopy and applications
- MRI in cancer diagnosis
- Breast Cancer Treatment Studies
- Corneal surgery and disorders
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Hepatocellular Carcinoma Treatment and Prognosis
- Space Satellite Systems and Control
- Artificial Intelligence in Healthcare and Education
- Ocular Oncology and Treatments
University of Miami
2014-2025
Sylvester Comprehensive Cancer Center
2013-2025
Neurological Surgery
2024
HistoryMiami
2014
Jackson Memorial Hospital
2012
University of Florida
2001
National High Magnetic Field Laboratory
2001
Abstract The apparent diffusion tensor (ADT) imaging method was extended to account for multiple components. A biexponential ADT experiment used obtain separate images of rapidly and slowly diffusing water fractions in excised rat spinal cord. fast slow component tensors were compared found exhibit similar gross features, such as fractional anisotropy, both white gray matter. However, there also some important differences, which are consistent with the different structures occupying...
Abstract Purpose The study evaluates rapid linear accelerator (Linac) single isocenter stereotactic radiosurgery (SRS) with Hyperarc for large target numbers. We compared to Gamma Knife (GK), which suffers from long treatment times and investigated causes of differences. Methods Linac SRS GK plans patients receiving 18 Gy the gross tumor volume (GTV) were evaluated mean brain dose 12 or more (V12 Gy) as toxicity correlates. Further investigations included patient‐based simulations 1–33...
Abstract An inductively coupled, chronically implanted short‐solenoid coil was used to obtain in vivo localized 1 H NMR spectra and diffusion‐weighted images from a rat spinal cord. A 5 × 8 mm two‐turn elliptically shaped solenoid rats at the site of T‐12 vertebral‐level laminectomy. Excitation achieved solely by 3 cm external surface coil, signal detection coupling coil. The image signal‐to‐noise ratio (SNR) obtained with inductively‐coupled compared that using linear or quadrature provided...
Adaptive radiotherapy is being used in few institutions patients with head and neck cancer having bulky disease using periodic computed tomography imaging accounting for volumetric changes tumor volume and/or weight loss. Limited data are available on ART the postoperative setting. We aim to identify parameters that would predict need whether should be applied setting.Twenty stage III-IV were prospectively accrued. A simulation was done prior treatment repeated at weeks 3 6 of concurrent...
Abstract Knowledge‐based planning ( KBP ) can be used to improve plan quality, speed, and reduce the inter‐patient variability. KPB may also identify systematic variations in VMAT plans, something very important multi‐institutional clinical trials. Training of a library is complex difficult process, models must validated prior their use. The purpose this work assess quality treatment plans generated using specific versus combined model for prostate cancer. Seven libraries were created from...
To assess the performance of a proton-specific knowledge based planning (KBPP) model in creation robustly optimized intensity-modulated proton therapy (IMPT) plans for treatment patients with prostate cancer.Forty-five localized cancer, who had previously been treated volumetric modulated arc therapy, were selected and replanned IMPT. A KBPP was generated from results 30 patients, remaining 15 patient used validation. The quality accuracy evaluated model-provided organ-at-risk regression...
To assess the performance of a proton-specific knowledge-based planning (KBP) model in creation robustly optimized intensity-modulated proton therapy (IMPT) plans for treatment advanced head and neck (HN) cancer patients. Seventy-three patients diagnosed with HN previously treated volumetric modulated arc (VMAT) were selected replanned IMPT. A KBP model, RapidPlanPT (RPP), was generated using 53 (20 unilateral cases 33 bilateral cases). The remaining 20 (10 10 cases) used validation....
Advances in magnetic resonance imaging (MRI) sequences allow physicians to define the dominant intraprostatic lesion (IPL) prostate radiation therapy treat-ments allowing for dose escalation and potentially increased tumor control. This work quantifies margin required around MRI-defined IPL accounting both motion deformation. Ten patients treated with a simultaneous integrated boost (SIIB) were retrospectively selected replanned incremental 1 mm margins from 0-5 determine if there any...
Objectives In this study, we outline our rationale for delivering a dose of ≥15 Gy in stereotactic radiosurgery (SRS) glomus jugulare tumor (GJT) while ensuring the avoidance complications associated with doses >13 to facial nerve. To avoid such complications, initially utilized Gamma Knife Perfexion (GK) system (Elekta Instrument AB, Stockholm, Sweden) at institution but encountered challenges related lengthy treatment times and difficulty sculpting minimize spare As potential solution,...
Purpose: Stereotactic body radiotherapy (SBRT) is used for spine treatments as it precisely delivers high radiation dose to tumors in close proximity organs-at-risk (OARs). The goal of this work evaluate dosimetric properties SBRT spinal with linear accelerators and CyberKnife (CK). Materials methods: Plans 27 patients, treated CK tumors, were also retrospectively optimized linac-based (LB) intensity-modulated (IMRT) volumetric modulated arc therapy (VMAT). One nine-field IMRT plan five VMAT...
Abstract Purpose Knowledge‐based planning (KBP) aims to automate and standardize treatment planning. New KBP users are faced with many questions: How much does model size matter, multiple models needed accommodate specific physician preferences? In this study, six head‐and‐neck were trained address these questions. Methods The differed in training plan composition: Full ( n = 203 plans), 101 101), 50 50), 25 25) plans from two physicians. A B each contained only one physician, respectively....