Giuseppe Carlo Iorio

ORCID: 0000-0003-1390-4191
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About
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Research Areas
  • Prostate Cancer Treatment and Research
  • Prostate Cancer Diagnosis and Treatment
  • Colorectal and Anal Carcinomas
  • Head and Neck Cancer Studies
  • Radiopharmaceutical Chemistry and Applications
  • Advanced Radiotherapy Techniques
  • Lymphoma Diagnosis and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer Diagnosis and Treatment
  • Brain Metastases and Treatment
  • COVID-19 and healthcare impacts
  • Colorectal Cancer Surgical Treatments
  • Oral health in cancer treatment
  • Medical Imaging Techniques and Applications
  • Lung Cancer Diagnosis and Treatment
  • Breast Cancer Treatment Studies
  • Gastric Cancer Management and Outcomes
  • Head and Neck Surgical Oncology
  • Management of metastatic bone disease
  • Inflammatory Biomarkers in Disease Prognosis
  • CNS Lymphoma Diagnosis and Treatment
  • Polyomavirus and related diseases
  • Lung Cancer Treatments and Mutations
  • Respiratory Support and Mechanisms

University of Turin
2017-2025

Collaborative Group (United States)
2023

Start Treatment & Recovery Centers
2023

Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2019-2022

Essen University Hospital
2022

Ospedale Policlinico San Martino
2022

University of Genoa
2022

TH Bingen University of Applied Sciences
2022

University of Tübingen
2022

Sapienza University of Rome
2011

Metastasis-directed therapy (MDT) has been tested in clinical trials as a treatment option for oligorecurrent prostate cancer (PCa). However, there is an ongoing debate regarding the impact of using different imaging techniques interchangeably defining lesions and guiding MDT within trials. <b>Methods:</b> We retrospectively identified PCa patients who had 5 or fewer nodal, bone, visceral metastases detected by choline prostate-specific membrane antigen (PSMA) PET/CT underwent stereotactic...

10.2967/jnumed.124.267586 article EN cc-by Journal of Nuclear Medicine 2024-06-21

Prostate-specific-membrane-antigen/positron emission tomography (PSMA-PET) detects with high accuracy disease-recurrence, leading to changes in the management of biochemically-recurrent (BCR) prostate cancer (PCa). However, data regarding oncological outcomes patients who performed PSMA-PET are needed. The aim this study was evaluate incidence clinically relevant events during follow-up for BCR after radical treatment.This analysis included consecutive, hormone-sensitive, hormone-free,...

10.1007/s00259-022-05741-9 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2022-02-26

Abstract Aim Radiation-induced oral mucositis (RIOM) is the most frequent side effect in head and neck cancer (HNC) patients treated with curative radiotherapy (RT). A standardized strategy for preventing treating RIOM has not been defined. of this study was to perform a real-life survey on management among Italian RT centers. Methods 40-question administered 25 radiation oncologists working different centers across Italy. Results total 1554 HNC have participating 2021, majority (median 91%)...

10.1007/s00520-023-08185-5 article EN cc-by Supportive Care in Cancer 2023-12-19

This exploratory prospective cohort study aimed to investigate the trajectory of psychological distress and posttraumatic growth (PTG) in rectal cancer patients from diagnosis follow-up explore factors that could predict PTG at follow-up. We assessed (anxiety depression), PTG, physical symptoms, quality life, cancer-related coping, state trait affectivity, resilience, alexithymia 43 patients, M (SD) age: 61.6 (12.6); 67.4% men, after (T0), preoperative radiochemotherapy (T1), surgical...

10.1037/tra0001835 article EN Psychological Trauma Theory Research Practice and Policy 2025-01-09

160 Background: Apalutamide+androgen deprivation therapy (ADT) showed to significantly improve overall survival in low and high volume metastatic hormone sensitive prostate cancer (mHSPC) if compared ADT alone. However, a randomized phase II trial (ARTO, NCT03449719) suggested that stereotactic body radiotherapy (SBRT) improved clinical outcomes when administered concomitantly with abiraterone acetate castration resistance (mCRPC). Nonetheless, evidence related use of SBRT addition androgen...

10.1200/jco.2025.43.5_suppl.160 article EN Journal of Clinical Oncology 2025-02-10

Background/Objectives: The management of oropharyngeal squamous cell carcinoma (OPSCC) often involves multidisciplinary decision-making to optimize patient outcomes. Surgery and chemoradiation therapy (CRT) represent the two main treatment modalities. aim this cross-sectional study was provide a comprehensive analysis quality life, speech, swallowing, sleep, psychological distress, nutritional status in OPSCC patients treated with either surgery or CRT. Methods: Thirty subjects were divided...

10.3390/diseases13040106 article EN cc-by Diseases 2025-04-02

Abstract Aim To report on clinical outcomes of simultaneous integrated boost intensity‐modulated radiation therapy (IMRT) and concurrent chemotherapy as per Radiation Therapy Oncology Group (RTOG) 0529 protocol in anal cancer patients. Methods Clinical stage T1–T4 N0–N3 patients were submitted to concomitant chemoradiation. Patients with cT2N0 disease prescribed 50.4 Gy/28 fractions the gross tumor planning target volume (PTV) 42 elective nodal PTV. staged cT3–T4/N0–N3 given 54 Gy/30...

10.1111/ajco.12768 article EN Asia-Pacific Journal of Clinical Oncology 2017-08-30

Background The COVID-19 pandemic has likely affected the most vulnerable groups of patients and those requiring time-critical access to healthcare services, such as with cancer. aim this study was use time trend data assess impact on timely diagnosis treatment head neck cancer (HNC) in Italian Piedmont region. Methods This based two different sources. First, regional hospital discharge register were used identify incident HNC ≥18 years old during period from January 1, 2015, December 31,...

10.3389/fpubh.2022.809283 article EN cc-by Frontiers in Public Health 2022-02-21

Concurrent chemo-radiation (CT-RT) is a standard therapy for squamous cell carcinoma of anal canal. Different clinical and biological factors may potentially affect outcome. We investigated the prognostic role baseline hemoglobin (Hb) in cohort cancer patients submitted to CT-RT with 5-fluorouracil mitomycin C. Up 161 stage T1-T4/N0-N3/M0 were treated. Response was assessed at 6 weeks thereafter 3, 12 months. Two different approaches used:a)simultaneous integrated boost following RTOG 05-29...

10.1186/s13014-018-1035-9 article EN cc-by Radiation Oncology 2018-05-01

Background: In anal cancer, there are no markers nor other laboratory indexes that can predict prognosis and guide clinical practice for patients treated with concurrent chemoradiation. this study, we retrospectively investigated the influence of immune inflammation indicators on treatment outcome cancer undergoing chemoradiotherapy. Methods: All had a histologically proven diagnosis squamous cell carcinoma canal/margin chemoradiotherapy according to Nigro’s regimen. Impact pre-treatment...

10.2147/cmar.s197349 article EN cc-by-nc Cancer Management and Research 2019-04-01

ObjectiveDelineation of treatment volumes is a major source uncertainties in radiotherapy (RT). This also true for rectal cancer patients undergoing neoadjuvant RT, with potential impact on quality. We investigated the role digital platform Anatom-e (Anatom-e Information Sytems Ltd., Houston, Texas) increasing compliance to follow specific protocol multicentric setting.Materials and methodsTwo clinical cases locally advanced were chosen. Participants instructed 2009 Radiation Therapy...

10.1016/j.ctro.2018.06.002 article EN cc-by-nc-nd Clinical and Translational Radiation Oncology 2018-06-01

The association between chronic idiopathic urticaria (CIU) and autoimmune thyroiditis (AT) is known, as well major prevalence of antithyroid antibodies in the allergical subjects other diseases. We have evaluated effects l-thyroxine on clinical symptoms CIU AT patients suggesting hypothesis a new thyroid-stimulating hormone (TSH) role immune system.In 20 female with + AT, both hypothyroid euthyroid, we investigated therapeutic dosed to suppress TSH. Free-T3, Free-T4, TSH, antithyroperoxidase...

10.1111/j.1398-9995.2005.00723.x article EN Allergy 2005-01-31

To evaluate clinical outcomes of simultaneous integrated boost (SIB) - intensity modulated radiotherapy (RT) in patients with non metastatic anal cancer compared to those a set treated 3-dimensional conformal RT and sequential (SeqB). A retrospective cohort 190 at 3 academic centers concurrent chemo-RT employing either SIB or SeqB was analysed. The SIB-group consisted 87 patients, 2 cycles Mitomycin (MMC) 5-Fluorouracil (5FU) using SIB-IMRT delivering 42-45Gy/28–30 fractions the elective...

10.1186/s13014-018-1124-9 article EN cc-by Radiation Oncology 2018-09-10
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