A5101761537- BRCA gene mutations in cancer
- Global Cancer Incidence and Screening
- Patient-Provider Communication in Healthcare
- Health Literacy and Information Accessibility
- Nutrition, Genetics, and Disease
- Climate Change Communication and Perception
- Genetically Modified Organisms Research
- Cardiovascular Health and Risk Factors
Columbia University
2015-2024
Columbia University Irving Medical Center
2017-2018
Background: Breast cancer risk assessment including genetic testing can be used to classify people into different groups with screening and preventive interventions tailored the needs of each group, yet implementation risk-stratified breast prevention in primary care settings is complex. Objective: To address barriers assessment, communication, strategies settings, we developed a Web-based decision aid, RealRisks, that aims improve preference-based decision-making for prevention,...
Introduction: Although the prevalence of a pathogenic variant in BRCA1 and BRCA2 genes is about 1:400 (0.25%) general population, as high 1:40 (2.5%) among Ashkenazi Jewish population. Despite cost-effective preventive measures for mutation carriers, Orthodox Jews constitute cultural religious group that requires different approaches to genetic testing relative other groups. This study analyzed dialog key stakeholders community members explore factors influence decision-making New York...
<b><i>Background/Aims:</i></b> Ashkenazi Jews have a 1:40 prevalence of <i>BRCA1/2</i> mutations. Orthodox are an understudied population with unique cultural and religious factors that may influence genetic testing uptake. <b><i>Methods:</i></b> Using mixed-methods approach, we conducted cross-sectional survey focus groups among Jewish women in New York/New Jersey to explore affecting decision-making about<i>...
Abstract This abstract was not presented at the symposium.
Abstract Background: The prevalence of BRCA1/2 mutations among Ashkenazi Jews is 1 in 40. Compared to family history-based BRCA testing, population-based testing has been shown detect more mutation carriers this population. Orthodox (OJ) are the largest and fastest-growing Jewish population NY represent a spectrum observance including Modern Orthodox, Yeshivish, Chassidic. This understudied unique social, cultural, religious factors that may influence genetic testing. We examined influencing...