A5005738861- Occupational Health and Performance
- Injury Epidemiology and Prevention
- BRCA gene mutations in cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nutrition, Genetics, and Disease
- Global Cancer Incidence and Screening
- Radiation Dose and Imaging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pregnancy-related medical research
- Occupational exposure and asthma
- Occupational Health and Safety Research
- Genetically Modified Organisms Research
- Statistical Methods and Bayesian Inference
- Asthma and respiratory diseases
- Statistical Methods in Clinical Trials
- Disaster Response and Management
- Suicide and Self-Harm Studies
- Advanced Causal Inference Techniques
- Noise Effects and Management
- Occupational and environmental lung diseases
- Traffic and Road Safety
- Sarcoidosis and Beryllium Toxicity Research
- Economic and Financial Impacts of Cancer
University of California, Berkeley
2021-2024
New York City Fire Department
2018-2023
Montefiore Medical Center
2018-2023
University School
2023
New York University
2023
Stanford University
2021
Albert Einstein College of Medicine
2020
Columbia University
2017-2018
Columbia University Irving Medical Center
2018
<h3>Importance</h3> Elevated incidence rates of thyroid cancer among World Trade Center (WTC)–exposed individuals may be associated with the identification asymptomatic cancers during medical surveillance. <h3>Objective</h3> To examine association between WTC exposure and Fire Department City New York (hereafter, Department) rescue/recovery workers as well <h3>Design, Setting, Participants</h3> This closed-cohort study classified method detection (asymptomatic symptomatic) in 14 987 men...
Sarcoidosis is a systemic granulomatous disease of unknown etiology. It may develop in response to an exposure or inflammatory trigger the background genetically primed abnormal immune response. Thus, genetic studies are potentially important our understanding pathogenesis sarcoidosis. We developed case-control study which explored variations between firefighters Fire Department City New York (FDNY) with World Trade Center (WTC)-related sarcoidosis and those WTC exposure, but without The...
The World Trade Center (WTC) attacks on 9/11/2001 have consistently been associated with elevated rates of physical and mental health morbidities, while evidence about mortality has limited. We examined between 9/12/2001 12/31/2017 among 15,431 WTC-exposed Fire Department the City New York (FDNY) firefighters emergency medical service providers (EMS), specifically assessing associations intensity WTC-exposure risk. Standardized ratios (SMR) 95% confidence intervals (CI) compared FDNY cohort...
Diet is a modifier of metabolic syndrome which in turn associated with World Trade Center obstructive airways disease (WTC-OAD). We have designed this study to (1) assess the dietary phenotype (food types, physical activity, and habits) Fire Department New York (FDNY) WTC-Health Program (WTC-HP) cohort (2) quantify association quality its advanced glycation end product (AGE) content development WTC-OAD. WTC-OAD, defined as developing WTC-Lung Injury (WTC-LI; FEV1 < LLN) and/or airway...
Abstract Background A recent study of World Trade Center (WTC)‐exposed firefighters and emergency medical service workers demonstrated that elevated thyroid cancer incidence may be attributable to frequent testing, resulting in the identification asymptomatic tumors. We expand on by comparing among three groups: WTC‐exposed rescue/recovery enrolled a New York State (NYS) WTC‐medical monitoring treatment program (MMTP); not an MMTP (non‐MMTP); NYS population. Methods Person‐time began...
Peripheral neuropathy can result from numerous conditions including metabolic disorders, inflammatory disease, or exposure to environmental biological toxins. We analyzed questionnaire data 9239 Fire Department of the City New York (FDNY) World Trade Center (WTC)-exposed firefighters and emergency medical service workers (EMS) evaluate association between work at WTC site subsequent peripheral symptoms using validated Diabetic Neuropathy Symptom (DNS) score. grouped population into an...
<b><i>Background/Aims:</i></b> Ashkenazi Jews have a 1:40 prevalence of <i>BRCA1/2</i> mutations. Orthodox are an understudied population with unique cultural and religious factors that may influence genetic testing uptake. <b><i>Methods:</i></b> Using mixed-methods approach, we conducted cross-sectional survey focus groups among Jewish women in New York/New Jersey to explore affecting decision-making about<i>...
1586 Background: The U.S. Preventive Services Task Force (USPSTF) recommends that women who meet family history criteria for hereditary breast and ovarian cancer (HBOC) be referred genetic counseling. However, HBOC testing is under-utilized, particularly among racial/ethnic minorities. We evaluated different methods of intake, including a validated screener, documentation in the electronic health record (EHR), web-based decision aid (DA). Methods: Among undergoing screening mammography, we...
The goal of this study was to estimate the impact exposure World Trade Center (WTC) site on annual and persistent rates otalgia hearing impairment among Fire Department City New York (FDNY) Firefighters Emergency Medical Service Workers (EMS).Responders completed routine physical health questionnaires at monitoring visits. We used logistic marginal regression models explore association between WTC arrival time.The highest-exposed group had greater odds ear symptoms (OR 1.33, 95%CI 1.11-1.59)...
Fire Department of New York (FDNY) rescue and recovery workers exposed to World Trade Center (WTC) particulates suffered loss forced expiratory volume in 1 s (FEV1). Metabolic Syndrome increased the risk developing WTC-lung injury (WTC-LI). We aim attenuate deleterious effects WTC exposure through a dietary intervention targeting these clinically relevant disease modifiers. hypothesize that calorie-restricted Mediterranean will improve metabolic risk, subclinical indicators cardiopulmonary...
Abstract The parametric g-formula is a causal inference method that appropriately adjusts for time-varying confounding affected by prior exposure. Like all methods, it assumes correct model specification, usually assessed comparing the observed outcome with simulated under no intervention (natural course). However, unclear how to evaluate natural course performance and whether other variables should also be considered. We reviewed current practices evaluating misspecification in applications...
OBJECTIVES/GOALS: Particulate matter (PM) and metabolic syndrome (MetSyn) increase risk of World Trade Center-Lung Injury (WTC-LI). Mediterranean-type diets have also been found to improve lung function. Fire Department New York 1st-responders with a high PM exposure at WTC MetSyn may improved function after Mediterranean dietary intervention. METHODS/STUDY POPULATION: Food Intake REstriction for Health OUtcome Support Education (FIREHOUSE) randomized clinical trial (RCT) assessed our...
Background The goals of this study were to assess the impact work at World Trade Center (WTC) site in relation new, post‐9/11/2001 (9/11) antibody hepatitis C Virus (anti‐HCV); and, evaluate secular trends WTC‐exposed male Fire Department New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. Methods FDNY monitors responder health through physical exams routine blood work. We used descriptive statistics compare trans‐9/11 post‐9/11 incidence prevalence from 2000...
e13038 Background: Breast cancer risk assessment and chemoprevention with anti-estrogens among high-risk women are underutilized. We developed web-based decision support tools for women, RealRisks, their primary care providers (PCPs), BNAV, which integrated into clinic workflow. Methods: conducted a pilot study in 50 who were found to have 5-year of invasive breast ≥1.67% according the Gail model during screening mammography. RealRisks includes modules on chemoprevention, as well interactive...
e13044 Background: One of the barriers to chemoprevention uptake among high-risk women is lack routine breast cancer risk assessment in primary care setting. We calculated using Breast Cancer Surveillance Consortium (BCSC) model, which accounts for age, race/ethnicity, first-degree family history cancer, benign disease, and mammographic density, data collected from electronic health record (EHR) compared self-report. Methods: Among undergoing screening mammography, we information EHR a...
Abstract Background: The prevalence of BRCA1/2 mutations among Ashkenazi Jews is 1 in 40. Compared to family history-based BRCA testing, population-based testing has been shown detect more mutation carriers this population. Orthodox (OJ) are the largest and fastest-growing Jewish population NY represent a spectrum observance including Modern Orthodox, Yeshivish, Chassidic. This understudied unique social, cultural, religious factors that may influence genetic testing. We examined influencing...
Abstract BACKGROUND. Diet is a modifier of metabolic syndrome which in turn associated with World Trade Center Obstructive Airways Disease(WTC-OAD). We have designed this study to 1. assess the dietary phenotype(food types, physical activity, and habits) Fire Department New York(FDNY) WTC-Health Program(WTC-HP) cohort 2. quantify association quality its advanced glycation end product(AGE) content development WTC-OAD. METHODS. WTC-OAD, defined as developing WTC-Lung Injury(WTC-LI;FEV 1...
Abstract BACKGROUND. Diet is a modifier of metabolic syndrome which in turn associated with World Trade Center Obstructive Airways Disease(WTC-OAD). We have designed this study to 1. assess the dietary phenotype(food types, physical activity, and habits) Fire Department New York(FDNY) WTC-Health Program(WTC-HP) cohort 2. quantify association quality its advanced glycation end product(AGE) content development WTC-OAD. METHODS. WTC-OAD, defined as developing WTC-Lung Injury(WTC-LI;FEV 1...
<h3>Introduction</h3> The highest suicide rates in the U.S. have been found among males construction, mining, and extraction occupations. In recent years, rate has increased dramatically, which may reflect lack of economic opportunities for miners. <h3>Objectives</h3> We examined impact job loss, both permanent temporary, on risk overdose a cohort 11,817 male miners from Diesel Exhaust Miners Study II. <h3>Methods</h3> calculated directly standardized age-adjusted incidence per 100,000...
<h3>Introduction</h3> Metalworking fluids (MWF) are complex mixtures of oils and chemical additives used to cool lubricate metal machining operations. Previous studies have reported increased risk specific cancers associated with MWF exposure. <h3>Objectives</h3> This report broadly examines cancer incidence in the United Auto Workers-General Motors (UAW-GM) cohort exposed MWFs extended follow-up (through 2015). The outcomes interest were melanoma, leukemia, non-Hodgkin lymphoma colon,...