David J. Prezant

ORCID: 0000-0001-9562-0330
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About
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Research Areas
  • Occupational Health and Performance
  • Injury Epidemiology and Prevention
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Disaster Response and Management
  • Cardiac Arrest and Resuscitation
  • Trauma and Emergency Care Studies
  • Occupational and environmental lung diseases
  • Pregnancy-related medical research
  • Traffic and Road Safety
  • Burn Injury Management and Outcomes
  • Air Quality and Health Impacts
  • Emergency and Acute Care Studies
  • Posttraumatic Stress Disorder Research
  • Respiratory Support and Mechanisms
  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Sarcoidosis and Beryllium Toxicity Research
  • Traumatic Brain Injury Research
  • Exercise and Physiological Responses
  • Occupational Health and Safety Research
  • Adipose Tissue and Metabolism
  • Disaster Management and Resilience
  • Occupational exposure and asthma
  • Smoking Behavior and Cessation

Montefiore Medical Center
2016-2025

New York City Fire Department
2016-2025

Albert Einstein College of Medicine
2016-2025

New York University
2002-2024

The Bronx Defenders
1989-2022

Indiana University School of Medicine
2020

Yeshiva University
2006-2019

Steinhauser (Czechia)
2019

American Thoracic Society
2017

Brooklyn College
2011-2016

Workers from the Fire Department of New York City were exposed to a variety inhaled materials during and after collapse World Trade Center. We evaluated clinical features in series 332 firefighters whom severe cough developed exposure prevalence severity bronchial hyperreactivity without classified according level exposure.

10.1056/nejmoa021300 article EN New England Journal of Medicine 2002-09-12

<h3>Importance</h3> Risk factors for out-of-hospital death due to novel coronavirus disease 2019 (COVID-19) are poorly defined. From March 1 April 25, 2020, New York City, (NYC), reported 17 118 COVID-19–related deaths. On 6, cardiac arrests peaked at 305 cases, nearly a 10-fold increase from the prior year. <h3>Objective</h3> To describe characteristics (race/ethnicity, comorbidities, and emergency medical services [EMS] response) associated with outpatient during COVID-19 pandemic in NYC....

10.1001/jamacardio.2020.2488 article EN cc-by JAMA Cardiology 2020-06-19

New York City Fire Department rescue workers experienced massive exposure to airborne particulates at the World Trade Center site. Aims of this longitudinal study were (1) determine if bronchial hyperreactivity was present, persistent, and independently associated with intensity, (2) identify objective measures shortly after collapse that would predict persistent a diagnosis reactive airways dysfunction 6 months post-collapse. A representative sample 179 stratified by intensity (high,...

10.1164/rccm.200211-1329oc article EN American Journal of Respiratory and Critical Care Medicine 2003-03-04

The terrorist attacks on the World Trade Center September 11, 2001, exposed thousands of Fire Department New York City (FDNY) rescue workers to dust, leading substantial declines in lung function first year. We sought determine longer-term effects exposure.Using linear mixed models, we analyzed forced expiratory volume 1 second (FEV(1)) both active and retired FDNY basis spirometry routinely performed at intervals 12 18 months from March 12, 2000, 2008.Of 13,954 who were present between 24,...

10.1056/nejmoa0910087 article EN New England Journal of Medicine 2010-04-07

We report a sentinel case of acute eosinophilic pneumonia in firefighter exposed to high concentrations World Trade Center dust during the rescue effort from September 11 24. The presented with Pa(O2) 53 mm Hg and responded oxygen corticosteroids. Computed tomography scan showed patchy ground glass density, thickened bronchial walls, bilateral pleural effusions. Bronchoalveolar lavage recovered 70% eosinophils, only 1% eosinophils peripheral blood. Eosinophils were not degranulated increased...

10.1164/rccm.200206-576oc article EN American Journal of Respiratory and Critical Care Medicine 2002-09-13

On September 11, 2001, the World Trade Center collapse created an enormous urban disaster site with high levels of airborne pollutants. First responders, rescue and recovery workers, residents have since reported respiratory symptoms developed pulmonary function abnormalities.To quantify health effects exposure in New York City Fire Department.Longitudinal study 12,079 Department workers employed on or before 09/11/2001. Between 01/01/1997 09/11/2002, 31,994 spirometries were obtained FEV(1)...

10.1164/rccm.200511-1736oc article EN American Journal of Respiratory and Critical Care Medicine 2006-04-28

We identified trends in the prevalence of elevated posttraumatic stress disorder (PTSD) risk as determined by Fire Department City New York (FDNY)-modified PTSD Checklist World Trade Center (WTC)-exposed firefighters. also examined relation to WTC exposure, social support, change recreational activities, and functional health.We analyzed 16,826 questionnaires from 10,074 firefighters yearly intervals, September 12, 2001, 11, 2005.The increased over time, 9.8% year 1 10.6% 4 (p < 0.0001)....

10.1177/003335491012500411 article EN Public Health Reports 2010-07-01

The collapse of the World Trade Center (WTC) on 11 September 2001 exposed New York City firefighters to smoke and dust unprecedented magnitude duration. chemicals concentrations produced from any fire are difficult predict, but estimates internal dose exposures can be assessed by biological monitoring blood urine. We analyzed urine specimens obtained 321 responding WTC fires for 110 potentially fire-related chemicals. Controls consisted 47 not present at WTC. Sampling occurred 3 weeks after...

10.1289/ehp.6315 article EN public-domain Environmental Health Perspectives 2003-09-09

Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among Health Registry enrollees. Cases diagnosed enrollment were included in a nested case–control study. Controls matched cases on age, sex, race or ethnicity, eligibility group (eg, rescue recovery worker). Results: identified 43 of Twenty-eight incident 109 controls...

10.1097/jom.0b013e31822a3596 article EN Journal of Occupational and Environmental Medicine 2011-09-01

Respiratory symptoms, either newly reported after the World Trade Center (WTC) disaster on 11 September 2001 (9/11) or increased in severity, have been well documented WTC-exposed workers and New York City residents. However, considerable uncertainty exists over persistence of symptoms.In this study, our goals were to describe trends post-9/11 respiratory gastro-esophageal reflux disease (GERD) symptoms firefighters examine symptom progression cohort that completed both year 1 4...

10.1289/ehp.0800291 article EN Environmental Health Perspectives 2009-02-10

Abstract Background Symptoms of post‐traumatic stress disorder (PTSD) have been reported even years after the terrorist attacks September 11, 2001 (9/11). Methods We used screening tools to assess prevalence probable PTSD in 9/11‐exposed firefighters at two time points, within 6 months 9/11 (baseline) and 3–4 post‐disaster (follow‐up). Results Five thousand six hundred fifty‐six individuals completed assessments both times. 15.5% post‐9/11, 8.6% baseline 11.1% follow‐up, on average 2.9 (SD...

10.1002/ajim.20894 article EN American Journal of Industrial Medicine 2010-09-22

Abstract Background This study examines the prevalence of physician‐diagnosed respiratory conditions and mental health symptoms in firefighters emergency medical service workers up to 9 years after rescue/recovery efforts at World Trade Center (WTC). Methods We analyzed Fire Department New York (FDNY) physician self‐reported diagnoses by WTC exposure quintiles pulmonary function (FEV1% predicted). used screening instruments assess probable post‐traumatic stress disorder (PTSD) depression....

10.1002/ajim.20993 article EN American Journal of Industrial Medicine 2011-08-17

Cross-sectional studies demonstrate an association between metabolic syndrome and impaired lung function.To define if biomarkers are risk factors for loss of function after irritant exposure.A nested case-control study Fire Department New York personnel with normal pre-September 11th FEV(1) who presented subspecialty pulmonary evaluation before March 10, 2008. We correlated obtained within 6 months World Trade Center dust exposure subsequent FEV(1). at 6.5 years defined disease status; cases...

10.1164/rccm.201109-1672oc article EN American Journal of Respiratory and Critical Care Medicine 2011-11-18
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