A5055131418- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Renal Transplantation Outcomes and Treatments
- Parvovirus B19 Infection Studies
- Ocular Diseases and Behçet’s Syndrome
- Lymphoma Diagnosis and Treatment
- Fungal Infections and Studies
- Virus-based gene therapy research
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Acute Myeloid Leukemia Research
- Neonatal Health and Biochemistry
- Childhood Cancer Survivors' Quality of Life
- Cutaneous lymphoproliferative disorders research
- Ocular Oncology and Treatments
- Cytomegalovirus and herpesvirus research
- Retinal and Optic Conditions
Manchester University NHS Foundation Trust
2023-2024
Children's Hospital at Westmead
2021-2024
Royal Manchester Children's Hospital
2022-2024
In high-risk myeloid malignancy, relapse is reduced using cord blood transplant (CBT) but remains the principal cause of treatment failure. We previously described T-cell expansion in CBT recipients receiving granulocyte transfusions. now report safety and tolerability such transfusions, data, immunophenotype, cytokine profiles clinical response children with post-transplant relapsed acute leukaemia who received T-replete, HLA-mismatched pooled granulocytes within a phase I/II trial...
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare and distinct subtype of peripheral lymphoma, representing <1% all non-Hodgkin lymphomas. SPTCL usually arises in the fourth decade life with multifocal involvement limbs trunk. Orbital disease uncommon. We present youngest known case orbital 3-year-old child, where diagnosis was initially confounded by lower eyelid mass masquerading as preseptal cellulitis. MRI revealed poorly defined anterior mass. Immunophenotyping...
This retrospective review reports on the management and outcomes of retinoblastoma in children treated at Children’s Hospital Westmead (CHW), Sydney. Results were compared to those a previous RB cases presenting between 1974 2005 same centre, which was published this journal. A all Medical 2008 2018 conducted. 67 patients included study with mean age presentation 23.5-months 9.2-months for unilateral bilateral disease respectively. All our cohort offered genetic testing. The rate germline...