A5049537601- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Particle Detector Development and Performance
- Advanced Fiber Laser Technologies
- Quantum Chromodynamics and Particle Interactions
- Solid State Laser Technologies
- Laser Design and Applications
- Laser-Matter Interactions and Applications
- Dark Matter and Cosmic Phenomena
- Neutrino Physics Research
- Semiconductor Lasers and Optical Devices
- Photonic Crystal and Fiber Optics
- Photorefractive and Nonlinear Optics
- Lung Cancer Diagnosis and Treatment
- Photonic and Optical Devices
- Spectroscopy and Laser Applications
- Reproductive Biology and Fertility
- Medical Imaging Techniques and Applications
- COVID-19 epidemiological studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced Frequency and Time Standards
- Optical Network Technologies
- Pluripotent Stem Cells Research
- Cell Image Analysis Techniques
- Geophysics and Sensor Technology
University of Michigan
2023-2025
Stanford University
2013-2024
Government of Catalonia
2024
A. Alikhanyan National Laboratory
2024
Atlas Scientific (United States)
2024
Trinity University
2021-2022
Forest Research
2021
Northern Research Station
2021
Klinikum rechts der Isar
2021
KfH Kuratorium für Dialyse und Nierentransplantation
2016-2021
The output of a laser-diode-pumped Nd:YAG laser with an intravcavity-doubling crystal exhibits large-amplitude fluctuations and longitudinal-mode instabilities. results experimental theoretical investigation these instabilities are described. arise from coupling the longitudinal modes oscillator by sum-frequency generation in nonlinear crystal. A rate-equation theory multilongitudinal-mode intracavity-doubling is presented that includes terms modeling frequency-doubling processes.
We discuss a refined, hybrid rf/optical technique for studying sub-Doppler saturated absorption/dispersion resonances with excellent precision and symmetry. Sensitivity is limited mainly by fundamental noise in the signal. Resonance profiles obtained I2 are remarkable agreement theory. The method promises new level of accuracy laser locking to an optical resonance.
Short-term probabilistic forecasts of the trajectory COVID-19 pandemic in United States have served as a visible and important communication channel between scientific modeling community both general public decision-makers. Forecasting models provide specific, quantitative, evaluable predictions that inform short-term decisions such healthcare staffing needs, school closures, allocation medical supplies. Starting April 2020, US Forecast Hub ( https://covid19forecasthub.org/ ) collected,...
Abstract Academic researchers, government agencies, industry groups, and individuals have produced forecasts at an unprecedented scale during the COVID-19 pandemic. To leverage these forecasts, United States Centers for Disease Control Prevention (CDC) partnered with academic research lab University of Massachusetts Amherst to create US Forecast Hub. Launched in April 2020, Hub is a dataset point probabilistic incident cases, hospitalizations, deaths, cumulative deaths due county, state,...
Abstract Short-term probabilistic forecasts of the trajectory COVID-19 pandemic in United States have served as a visible and important communication channel between scientific modeling community both general public decision-makers. Forecasting models provide specific, quantitative, evaluable predictions that inform short-term decisions such healthcare staffing needs, school closures, allocation medical supplies. Starting April 2020, US Forecast Hub ( https://covid19forecasthub.org/ )...
We have generated pulses as short 4 psec at 1530 nm from a mode-locked erbium-doped fiber laser. The mode locker is wide-bandwidth, lithium niobate guided-wave modulator, and the laser completely integrated. present evidence that soliton pulse shaping playing key role in formation of pulses.
Single-frequency output power of 35 mW has been observed in 3.0% doped Nd:YVO/sub 4/ pumped with a 200-mW laser diode. The single-frequency operation is due to the spatial overlap longitudinal modes at surface mirror cavity where material pumped. strong absorption coefficient 808.7 nm and narrow bandwidth only allow single mode operate. effect modeled theoretically compared experiment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A new method of stabilizing the output frequency a He-Ne laser in longitudinal magnetic field has been developed. With simple modifications to standard tube we obtain stability <1 MHz (<10(-9)) for an averaging time 1 sec and long term (5 months) reproducibility ~ +/-1 MHz.
We have compressed the 80-psec pulses from a cw mode-locked Nd:YAG laser by factor of 45. The pulse compressor uses single-mode optical fiber and compact grating-pair dispersive delay line.
We have compressed the output of a synchronously pumped cavity-dumped dye laser with fiber–prism pulse compressor. The prism pair consisted two dense flint glass prisms, which were used at grazing exit angle to increase dispersive power. present results several experiments in we demonstrated 85% throughput, high compression ratios, and pulses as short 50 fsec.
I report the observation of continuous-wave laser oscillation in a Nd:YAG sphere. The spherical is excited by dye that focused to pump selectively certain regions With careful mode matching, single-frequency obtained. observed emission patterns agree well with modes predicted classical treatment spherically symmetric resonator. These are described products harmonics and Bessel functions, contrast standard Gaussian-beam linear cavity.
We have pumped a fiber Raman laser with continuous-wave mode-locked Nd:YAG operating at 1319 nm and generated pulses as short 160 fsec by using soliton pulse shaping in the fiber. also constructed completely integrated oscillator loop fiber-optic coupler fusion splicing.
We describe a technique for fabricating fast well-corrected cylindrical microlenses applications such as collimating laser diodes and coupling light into out of integrated optics devices. The lenses are produced by first grinding glass preform to desired cross-sectional shape then heating drawing the fiber diameter. operations polish surface reduce dimensions but maintain shape. Diffraction-limited 220-microm focal length immersion with numerical aperture >0.6 have been demonstrated.
The timing fluctuations of a mode-locked Nd:YAG laser are reduced by electronic feedback. Timing at rates 50 to 250 Hz more than 20 dB, the total from 2.9 0.9 psec rms, and long-term drift is 0.5 psec/min. Applications include time-resolved probing experiments synchronization lasers.
We present evidence-based design principles for three different UV-C based decontamination systems N95 filtering facepiece respirators (FFRs) within the context of SARS-CoV-2 outbreak 2019-2020. The approaches used here were created with consideration needs low- and middle-income countries (LMICs) other under-resourced facilities. As such, a particular emphasis is placed on providing cost-effective solutions that can be implemented in short order using generally available components...
Gene expression is a complex phenomenon involving numerous interlinked variables, and studying these variables to control essential in bioengineering biomanufacturing. While cloning techniques for achieving plasmid libraries that cover large design spaces exist, multiplex offering cell culture screening at similar scales are still lacking. We introduced microcapillary array-based platform aimed high-throughput, of miniature cultures through fluorescent reporters. The clone recovery mechanism...
The performance of diode bar pumped Nd:YAG and Nd:YLF lasers in a novel tightly folded resonator configuration is described. For at pump level 9.2 W TEM/sub 00/ output power 3.1 with slope efficiency 47% was observed. In Q-switched operation pulse energy 0.7 mJ pulsewidth 5 ns were obtained. same design configured to operate as an optical amplifier provides small-signal gain 28 dB average powers greater than 1 W. >
The regulation of chromatin structure and, therefore, transcriptional activity histone proteins by reversible lysine acetylation is an important posttranslational modification. Inhibitors deacetylase (HDAC) are considered as promising new anti-neoplastic drugs. hydroxamic acid SAHA e.g. currently used in the treatment advanced primary cutaneous T-cell lymphoma. EGFR protein tyrosine kinase inhibitor erlotinib a prominent drug cancer chemotherapy and approved for non-small cell lung cancer....
Automated cell segmentation and tracking is essential for dynamic studies of cellular morphology, movement, interactions as well other behaviors. However, accurate, automated, easy-to-use remains a challenge, especially in cases high densities, where discrete boundaries are not easily discernable. Here, we present fully automated algorithm that iteratively segments cells based on the observed distribution optical volumes measured by quantitative phase microscopy. By fitting these...
Ultraviolet decontamination of personal protective equipment, particularly masks, is important in situations where mask reuse practiced. To assist the development UV-C chambers, we have constructed ray tracing models Zemax OpticStudio v20.1 for two distinct geometries, namely, a rectangular cabinet and cylindrical can. These provide irradiance distributions that can be used comparison with experiment, as well to predict local variation over surface mask. In this paper describe model details,...