In acoustofluidic manipulation and sorting devices, Rayleigh streaming flows are typically found in addition to the acoustic radiation forces. However, experimental work from various groups has described that occurs planar devices a plane parallel transducer face. This is four-quadrant pattern with circulation transducer. Understanding its origins essential for creating designs limit or control this phenomenon. The cause of kind not been previously explained as it different well-known...

Ultrasonic treatment is an effective method for size refinement and dispersion of nanomaterials during their synthesis process. However, the quantitative relationship between ultrasonic conditions particle in metal nanoparticles has not been fully revealed. In this study, Cu were synthesized via wet-chemical redox under treatment, statistical analysis on evolution distribution was carried out. It found that decreased exponentially with increasing power. A model then proposed to describe...

This article discusses three-dimensional (3D) boundary-driven streaming in acoustofluidic devices. Firstly, the 3D Rayleigh pattern a microchannel is simulated and its effect on movement of microparticles various sizes demonstrated. The results obtained from this model show good comparisons with experimental visualisations demonstrate fully nature acoustic field associated acoustophoretic motion method then applied to another device order gain insights into an unusual in-plane pattern....

Numerical simulations of acoustic streaming flows can be used not only to explain the complex phenomena observed in acoustofluidic manipulation devices, but also predict and optimise their performances. In this paper, two numerical methods based on perturbation theory are compared order demonstrate viability applicability for modelling boundary-driven systems. It was found that Reynolds stress method, which predicts fields from driving terms, effectively resolve both inner outer mechanisms a...

While Chladni patterns in air over vibrating plates at macroscale have been well studied, inverse water microscale recently reported. The underlying physics for the focusing of microparticles on interface, however, is still unclear. In this paper, we present a quantitative three-dimensional study acoustophoretic motion clamped circular plate contact with emphasis roles acoustic radiation and streaming-induced drag forces. numerical simulations show good comparisons experimental observations...

Classical Rayleigh streaming is well known and can be modelled using Nyborg’s limiting velocity method as driven by fluid velocities adjacent to the walls parallel axis of main acoustic resonance. We have demonstrated previously existence mechanism four-quadrant transducer plane patterns in thin-layered acoustofluidic devices which are on perpendicular propagation. recently found experimentally that there a third case resembles but more complex pattern related three-dimensional cavity modes...

While acoustic streaming patterns in microfluidic channels with rectangular cross-sections have been widely shown the literature, boundary-driven fields non-rectangular not well studied. In this paper, a two-dimensional numerical model was developed to simulate on of cylindrical fluid channels. Firstly, linear pressure at resonant frequencies were solved from Helmholtz equation. Subsequently, outer bulk modelled while using Nyborg’s limiting velocity method, which equations extended be...

Efficient and controllable gene/drug delivery triggered by sonoporation is critical to cellular therapy. This study reports on repairable for massive cells trapped a phononic crystal plate (PCP). mechanism generated the effects of enhanced near-boundary streaming around manipulated cells. The achieved significantly improving tangential acoustic field gradient along cell boundary through resonant PCP excitation nonleaky Lamb modes intrinsically existing in uniform plate. structured...

In this Letter, we report two-dimensional focusing of microparticles in a glass capillary whose cross section is square outside and round inside using bulk acousto-microfluidics. An imaging system allowing measurements three-dimensional microparticle acoustophoresis designed to simultaneously present the processes from combinations vertical lateral views same frame. The underlying mechanisms device are explained by full-device numerical model, which solves coupling ultrasonic transducer,...

The appropriate planning of infrastructure protects people’s lives and property. Fire stations are an essential part a city’s they must be precisely located to shorten emergency response times reduce casualties. Recently, the focus city service has shifted from fire suppression technical rescues. We compared spatial distribution rescues at scale show variation in their influences. An integrated road-network accessibility location-allocation model (RNALA) for location station was proposed....

Classical Chladni patterns formed by vibrations of flat plates have been studied for centuries and are well understood. In this Letter, we show dexterous formation unconventional in a fluid using standing bulk acoustic waves. A neat acoustofluidic resonator enabling visualization microparticles the channel both on its cross section flow direction was designed. contrast to classical patterns, which depend resonant modes plates, herein generated cylindrical walls related channels. The behavior...

We present the acoustophoretic motion of microparticles simultaneously driven by acoustic streaming induced drag force (ASF) and radiation (ARF) on a phononic crystal plate (PCP). A much faster acoustophoresis can be achieved via PCP than traditional standing wave in bulk surface devices. The mechanism is attributed to significantly enhanced ASF ARF originating from resonant excitation nonleaky zero-order antisymmetric Lamb mode intrinsically plate, which generates highly localized field...

In ultrasonic micro-devices, contrast agent micro-bubbles are known to initiate cavitation and streaming local cells, potentially compromising cell viability. Here we investigate the effects of US alone by omitting monitoring viability under moderate-to-extreme ultrasound-related stimuli. Suspended H9c2 cardiac myoblasts were exposed fields within a glass micro-capillary their monitored different US-related An optimal injection flow rate 2.6 mL/h was identified in which, high maintained...

Acoustic streaming (fluid flow due to acoustic absorption) is observed in many devices designed manipulate cells and particles with ultrasound. The authors show that higher-order patterns exist previously reported transducer-plane streaming, investigate the conditions under which they occur. Interaction of both standing traveling waves required generate vorticity intensity underlies this phenomenon. This study illustrates how subtleties underlying physics can significantly affect behavior...

Studies on the bioeffects produced by ultrasound and microbubbles have focused primarily transport in bulk tissue, drug uptake individual cells, disruption of biological membranes. Relatively little is known about physical perturbations fluid dynamics intracellular environment during exposure. To investigate this, a custom acoustofluidic chamber was designed to expose model form giant unilamellar vesicles, microbubbles. The motion fluorescent tracer beads within lumen vesicles tracked...

We demonstrate a type of boundary-driven streaming in subwavelength slit (the width is smaller than the acoustic wavelength) between two phononic crystal plates (PCPs) by using limiting velocity method. It found that this has characteristics four-quadrant similar to classical Rayleigh streaming, and width, larger maximum streaming. The demonstrated approximately four orders magnitude higher rigid with same 15 μm. In addition, case vortex sizes are related lattice constant PCPs, which can be...

We report on a wave-driven microfluidic ultrasonic shaker that can stably trap and oscillate microparticles in water microchannel. The shaking system mainly consists of chip two orthogonally excited piezoelectric transducers: one for creating radiation force potential wells three-dimensional trapping the other generating sound destabilization to shake trapped microparticles. It is shown standing waves different but close frequencies provide [approximately...

In this Letter, we present an experimental method that allows simultaneous imaging of microparticles in horizontal and vertical planes a microchannel using single objective lens to be achieved. This is done by implementing specialized dual-prism arrangement, i.e., placing two 67.5° right triangular prisms between the microfluidic channel. Apart from demonstrating orthogonal discussing applicability configuration for efficient imaging, examples are also given microparticle alignment motion...

The ability to settle particles in a fluid has significant impact on many applications fields like biology, chemistry, environment, and industrial processing. Here, we set up an acoustofluidics framework, based equilateral-triangular-channel design, which can generate vertically asymmetric acoustic pressure profiles result unidirectionally downward radiation force streaming-induced drag the nodal plane, enabling rapid agglomeration sedimentation of microparticles toward channel wall. This...

Dielectrophoresis-field flow fractionation (DEP-FFF) is a promising method of fractionating particles from continuous and has considerable application potential in the fields biomedical, chemical, environmental engineering. Particle deformation an important issue DEP-FFF, having critical influence on accuracy viability bioparticles. However, this problem been largely ignored both theoretical numerical investigations. In present work, hybrid lattice Boltzmann scheme introduced to study soft...