A5100408462- Biosensors and Analytical Detection
- SARS-CoV-2 detection and testing
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Renal Diseases and Glomerulopathies
- Mass Spectrometry Techniques and Applications
- Click Chemistry and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Amino Acid Enzymes and Metabolism
- Supramolecular Self-Assembly in Materials
- Machine Learning in Materials Science
- melanin and skin pigmentation
- Dialysis and Renal Disease Management
- Protein purification and stability
- Phytochemicals and Antioxidant Activities
- MXene and MAX Phase Materials
- Insect-Plant Interactions and Control
- Wound Healing and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Selenium in Biological Systems
- Renal cell carcinoma treatment
- Insect Resistance and Genetics
- Hepatitis B Virus Studies
Beijing Institute of Technology
2025
Washington University in St. Louis
2021-2024
Leiden University
2024
Shandong University of Traditional Chinese Medicine
2024
Ministry of Agriculture and Rural Affairs
2024
Changsha University of Science and Technology
2022
Iowa State University
2021
City University of Hong Kong
2013
A MXene-based composite aerogel enabling highly efficient photothermally driven membrane distillation with dual-mode anti-biofouling properties make it appealing for solar-driven desalination.
Abstract Cells rely heavily on the uptake of exogenous nutrients for survival, growth, and differentiation. Yet quantifying small molecule at single cell level is difficult. Here we present a new approach to studying nutrient in live cells using Inverse Electron‐Demand Diels Alder (IEDDA) chemistry. We have modified carboxyfluorescein‐diacetate‐succinimidyl esters (CFSE)—a quenched fluorophore that can covalently react with proteins only turned cytosol following esterase activity—with...
Abstract Wound repair in adults lacks natural regenerative capacity seen during fetal period, frequently resulting the formation of tissue fibrosis and functional impairments. By transforming process into healing, it is possible to restore original state significantly enhance human health. Advanced treatment methods, e.g., a wearable patch with ultrasound electrical stimulation, offer promising solutions for wound regeneration by overcoming limitations traditional approaches such as skin...
Novel methods that enable sensitive, accurate and rapid detection of RNA would not only benefit fundamental biological studies but also serve as diagnostic tools for various pathological conditions, including bacterial viral infections cancer. Although highly existing involve long turn-around time extensive capital equipment. Here, an ultrasensitive amplification-free quantification method is demonstrated by integrating CRISPR-Cas13a system with ultrabright fluorescent nanolabel, plasmonic...
Abstract Aphis spiraecola Patch is one of the most economically important tree fruit pests worldwide. The pyrethroid insecticide lambda-cyhalothrin commonly used to control A. . In this 2-year study, we quantified resistance level in different regions Shaanxi province, China. results showed that had reached extremely high levels with a 174-fold ratio (RR) found Xunyi region. addition, compared enzymatic activity and expression P450 genes among eight populations. was significantly increased...
Autosomal dominant tubulointerstitial kidney disease (ADTKD)-uromodulin (
Abstract Enzyme‐linked immunosorbent assay is widely utilized in serologic assays, including COVID‐19, for the detection and quantification of antibodies against SARS‐CoV‐2. However, due to limited stability diagnostic reagents (e.g., antigens serving as biorecognition elements) biospecimens, temperature‐controlled storage handling conditions are critical. This limitation among others makes biodiagnostics resource‐limited settings, where refrigeration electricity inaccessible or unreliable,...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly spread and resulted in the global pandemic of COVID-19. Although IgM/IgG serology assay been widely used, with entire spike or nucleocapsid antigens, they only indicate presence absence antibodies against these proteins but are not specific to neutralization antibodies, therefore providing generic information about infection stage possible future immune protection. Novel technologies enabling easy-to-use sensitive...
Traditional cold chain systems of collection, transportation, and storage biofluid specimens for eventual analysis pose a huge financial environmental burden. These are impractical in pre-hospital resource-limited settings, where refrigeration electricity not reliable or even available. Here, we develop an innovative technology using metal-organic frameworks (MOFs), novel class organic-inorganic hybrids with high thermal stability, as encapsulates preserving the integrity protein biomarkers...
Abstract Cells rely heavily on the uptake of exogenous nutrients for survival, growth, and differentiation. Yet quantifying small molecule at single cell level is difficult. Here we present a new approach to studying nutrient in live cells using Inverse Electron‐Demand Diels Alder (IEDDA) chemistry. We have modified carboxyfluorescein‐diacetate‐succinimidyl esters (CFSE)—a quenched fluorophore that can covalently react with proteins only turned cytosol following esterase activity—with...
ABSTRACT To explore the influence of storage temperature and time on stability different concentrations hepatitis C virus nucleic acid (HCV RNA) samples to provide data reference for laboratory quality control. Serum 10 patients with HCV RNA detection quantitation 6 –10 8 IU/mL were collected. The each patient diluted into three concentrations: high, medium, low. Then concentration divided 21, which groups according conditions −20°C, 4°C, 25°C, seven in group. selected from group...
Article Effect of Protein Loading Density on the Structure and Biopreservation Efficacy Metal-Organic Frameworks Yixuan Wang 1,2, Sirimuvva Tadepalli 3,†, Harsh Baldi Jeremiah J. Morrissey 1,4 Srikanth Singamaneni 1,2,4,* 1 Department Mechanical Engineering Materials Science, Washington University in St. Louis, MO 63130, USA 2 Institute Science Engineering, 3 Radiation Oncology-Radiation Physics, Stanford School Medicine, Stanford, CA 94305, 4 Siteman Cancer Center, Barnes-Jewish Hospital,...
Short non-coding RNAs, which are known as microRNAs (miRNAs), play a key role in fundamental cellular processes by post-transcription regulations. This paper reports paper-based miRNA exponential amplification and detection system for rapid analysis of miRNAs. The sensor consists silicone frame, glass microfiber pads the storage reaction reagents, polyethersulfone flow channel sample delivery, two transparent adhesive films to seal inside chambers. results showed that can detect miRNA-223...