A5100444218- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Marine Bivalve and Aquaculture Studies
- Flavonoids in Medical Research
- Phytochemical Studies and Bioactivities
- Aquaculture Nutrition and Growth
- Phytochemicals and Antioxidant Activities
- Antibiotic Resistance in Bacteria
- Marine Biology and Environmental Chemistry
- Bacterial Identification and Susceptibility Testing
- Spectroscopy and Laser Applications
- Chromatography in Natural Products
- Metabolomics and Mass Spectrometry Studies
- Polysaccharides and Plant Cell Walls
- Neurobiology and Insect Physiology Research
- Advanced Chemical Sensor Technologies
- Industrial Vision Systems and Defect Detection
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Medicinal Plant Pharmacodynamics Research
- Spectroscopy and Chemometric Analyses
- Plant-based Medicinal Research
- Antimicrobial Resistance in Staphylococcus
- Food Quality and Safety Studies
State Ethnic Affairs Commission
2022-2025
Southwest Minzu University
2015-2025
Macau University of Science and Technology
2015-2025
Sichuan Normal University
2022-2025
Ocean University of China
2016-2025
Zhengzhou University of Light Industry
2015-2024
Nanjing Drum Tower Hospital
2014-2024
Hainan Tropical Ocean University
2022-2024
Zhejiang University
2015-2024
Jinhua Central Hospital
2018-2024
Gold colloids with nanoparticles of different sizes were found to enhance the chemiluminescence (CL) luminol-H2O2 system, and most intensive CL signals obtained 38-nm-diameter gold nanoparticles. UV-visible spectra, X-ray photoelectron transmission electron microscopy studies carried out before after reaction investigate enhancement mechanism. The by system was supposed originate from catalysis nanoparticles, which facilitated radical generation electron-transfer processes taking place on...
Abstract Reconstructing the genomes of bilaterian ancestors is central to our understanding animal evolution, where knowledge from ancient and/or slow-evolving lineages critical. Here we report a high-quality, chromosome-anchored reference genome for scallop Patinopecten yessoensis , bivalve mollusc that has with many ancestral features. Chromosome-based macrosynteny analysis reveals striking correspondence between 19 chromosomes and 17 presumed linkage groups at level conservation...
Abstract 5‐Fluorouracil (5‐ FU ) is one of the most commonly used chemotherapeutic agents in colon cancer treatment, but has a narrow therapeutic index limited by its toxicity. Melatonin exerts antitumor activity various cancers, it never been combined with 5‐ as an anticolon treatment to improve effect . In this study, we assessed such combinational use and investigated whether melatonin could synergize We found that significantly enhanced ‐mediated inhibition cell proliferation, colony...
Optimal treatment for resectable esophageal squamous cell carcinoma (ESCC) is controversial, especially in the context of potential benefit combining PD-1 blockade with neoadjuvant therapy. This phase 2 study aimed to assess camrelizumab plus chemotherapy this population. Patients (clinical stage II-IVA) received two cycles chemoimmunotherapy (NIC) (200 mg on day 1) nab-paclitaxel (260 mg/m2 total 1 and 8) cisplatin (75 days 1-3) each 21-day cycle. Surgery was performed approximately 6 weeks...
Disassembly planning aims to perform the optimal disassembly sequence given a used or obsolete product in terms of cost and environmental impact. This paper presents new multiobjective programming model for target sequencing. It proposes an improved ant colony algorithm derive sequences. work also establishes some indices on scheme evaluation fuzzy integral method evaluate obtained scheme. A CNC machine tool example is illustrate proposed models effectiveness algorithm. Both theoretical...
Resveratrol is widely known for its antiaging properties and exerts cardiovascular protective effects in different experimental models. The role of resveratrol regulating mitochondrial functions dynamics during the cardiac aging process remains poorly understood. In this study, on morphology depolarization expressions Drp1, parkin, PINK1, LC3 were investigated H9c2 cells after D‐galactose treatment that induced senescent‐like cardiomyocytes. results show downregulation Drp1 markedly...
Carbapenemase-producing Klebsiella pneumoniae (CPKP) strains have emerged as a major problem for healthcare systems. The aim of this study was to determine the circulating clones and analyze clinical molecular characteristics CPKP in our hospital.A total 74 carbapenemase producers collected from hospital 2012 2014 were analyzed prevalence extended-spectrum β-lactamase (ESBLs), plasmid-mediated quinolone resistance genes (PMQRs), exogenously acquired 16S rRNA methyltransferase (16S-RMTase),...
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) (PL) is a naturally occurring yellow pigment found in the plants of Plumbaginaceae, Droseraceae, Ancistrocladaceae, and Dioncophyllaceae families. It has been reported that PL exhibits anticarcinogenic, anti-inflammatory, analgesic activities. However, mechanism underlying its anti-inflammatory action remains unknown. In current study, we investigated characterized effects orally administrated range dosages from 5 to 20 mg/kg. We also...
Mitochondrial dysfunction is a prominent feature of ischemia heart disease but the underlying mechanism dynamics (fusion/fission) still unclear. Here we investigated novel function and Rg1 on an in vitro cardiomyocyte model hypoxia/reoxygenation (H/R). Cellular cytotoxicity was evaluated by MTT, mitochondrial viable staining, cardiac marker detection. ATP content measurement, MMP determination, ROS, OCR ECAR assay. Live-cell imaging with time-lapse fluorescence microscopy morphological...
Drying is an essential post-harvest processing technique used to improve the utilization efficiency of fresh fruit. The browning Choerospondias axillaris fruits during drying process can reduce their overall quality. In this study, we investigated relationship between degree and polyphenolics in C. fruits. Different samples dried by freeze (FD), microwave (MD), hot air (HAD) methods, respectively, exhibited color differences (ΔE) ranging from 14.53 64.78. UPLC-Q-Exactive Orbitrap-MS analysis...
The reaction of gold nanoparticles with a potassium periodate−sodium hydroxide−carbonate system undergoes chemiluminescence three emission bands at 380−390, 430−450, and 490−500 nm, respectively. It was found that the light intensity increased linearly concentration nanoparticles, CL dramatically when citrate ions on nanoparticle surface were replaced by SCN-. shape, size, oxidation state after chemiluminescent characterized UV−visible absorption spectrometry, transmission electron...
Light emission at approximately 415 nm was observed for gold particles with diameters of 2.6-6.0 dispersed in a solution containing bis(2,4,6-trichlorophenyl) oxalate and hydrogen peroxide. It found that the light intensity independent protecting reagents nanoparticles similar size, 5.0 6.0 diameter stronger than 2.6 2.8 diameter, increased linearly concentration using 6.0-nm nanoparticles. The were identified as emitting species, quantum yield determined to be (2.8 +/- 0.3) x 10(-5) is...
Klebsiella pneumoniae is a frequent nosocomial pathogen, with the multidrug-resistant (MDR) K. being major public health concern, frequently causing difficult-to-treat infections worldwide. The aim of this study was to investigate molecular characterization clinical MDR isolates. A total 27 non-duplicate isolates CTX-CIP-AK resistance pattern were investigated for prevalence antimicrobial genes including extended spectrum β-lactamase (ESBLs), plasmid-mediated quinolone (PMQR) genes, 16S rRNA...
A dinuclear gold(I) pyrrolidinedithiocarbamato complex (1) with a bidentate carbene ligand has been constructed and shows potent in vitro cytotoxic activities towards cisplatin-resistant ovarian cancer cells A2780cis. Its rigid scaffold enables zinc(II)-based metal-organic framework (Zn-MOF) to be used as carrier facilitating the uptake release of 1 solutions. Instead using conventional dialysis approach for drug-release testing, this study, set transwell assay-based experiments have...