A5101633559- Neural Networks Stability and Synchronization
- Genetic and phenotypic traits in livestock
- Neural Networks and Applications
- Genetic diversity and population structure
- Genetic Mapping and Diversity in Plants and Animals
- Marine Bivalve and Aquaculture Studies
- stochastic dynamics and bifurcation
- Advanced Memory and Neural Computing
- Aquaculture Nutrition and Growth
- Marine Biology and Ecology Research
- Image and Signal Denoising Methods
- Meat and Animal Product Quality
- Echinoderm biology and ecology
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Medical Image Segmentation Techniques
- Protein Hydrolysis and Bioactive Peptides
- Advanced Image Fusion Techniques
- Genomics and Phylogenetic Studies
- Marine and coastal ecosystems
- Marine Biology and Environmental Chemistry
- Stability and Controllability of Differential Equations
- Nonlinear Dynamics and Pattern Formation
- Microbial Community Ecology and Physiology
- Glaucoma and retinal disorders
Zhejiang University of Technology
2025
Ocean University of China
2015-2024
Hainan Tropical Ocean University
2022-2024
Tsinghua University
2024
Qianjiang Central Hospital
2024
Qingdao National Laboratory for Marine Science and Technology
2022
Beijing University of Chemical Technology
2022
University of Pittsburgh
2022
Northwest A&F University
2021
University of Wisconsin–Madison
2020
Abstract Reconstructing the genomes of bilaterian ancestors is central to our understanding animal evolution, where knowledge from ancient and/or slow-evolving lineages critical. Here we report a high-quality, chromosome-anchored reference genome for scallop Patinopecten yessoensis , bivalve mollusc that has with many ancestral features. Chromosome-based macrosynteny analysis reveals striking correspondence between 19 chromosomes and 17 presumed linkage groups at level conservation...
Bivalve molluscs are descendants of an early-Cambrian lineage superbly adapted to benthic filter feeding. Adaptations in form and behavior well recognized, but the underlying molecular mechanisms largely unknown. Here, we investigate genome, various transcriptomes, proteomes scallop Chlamys farreri, a semi-sessile bivalve with well-developed adductor muscle, sophisticated eyes, remarkable neurotoxin resistance. The scallop's large striated muscle is energy-dynamic not fully differentiated...
Abstract Dendritic cell (DC) maturation is a crucial process for antigen presentation and the initiation of T cell‐mediated immune responses. Toll‐like receptors play pivotal roles in stimulating DC promoting presentation. Here, novel message RNA (mRNA) cancer vaccine reported that boosts antitumor efficacy by codelivering an mRNA encoding tumor TLR7/8 agonist (R848) to using supramolecular lipid nanoparticles (SMLNP) as delivery platform, which new ionizable (N2‐3L) remarkably enhances...
Echinoderms exhibit several fascinating evolutionary innovations that are rarely seen in the animal kingdom, but how these animals attained such features is not well understood. Here we report sequencing and analysis of genome extensive transcriptomes sea cucumber
Abstract Insufficient accumulation of lipid nanoparticles (LNPs)‐based mRNA vaccines in antigen presenting cells remains a key barrier to eliciting potent antitumor immune responses. Herein, we develop dendritic (DCs) targeting LNPs by taking advantage mannose receptor‐mediated endocytosis. Efficient delivery DCs is achieved vitro and vivo utilizing the sweet (STLNPs‐Man). Intramuscular injection vaccine (STLNPs‐Man@mRNA OVA ) results four‐fold higher uptake comparison with commercially used...
Abstract The recently developed 2b-restriction site-associated DNA (2b-RAD) sequencing method provides a cost-effective and flexible genotyping platform for aquaculture species lacking sufficient genomic resources. Here, we evaluated the performance of this in selection (GS) Yesso scallop ( Patinopecten yessoensis ) through simulation real data analyses using six statistical models. Our analysis revealed that prediction accuracies obtained 2b-RAD markers were slightly lower than those all...
Cancer invasion of tissue is a key aspect the growth and spread cancer crucial in process metastatic spread, i.e., secondary cancers. Invasion consists cells secreting various matrix degrading enzymes (MDEs) which destroy surrounding or extracellular (ECM). Through combination proliferation migration, then actively locally into tissue. Thus processes occurring at level individual eventually give rise to level. In this paper we introduce new type multiscale model describing Our two-scale...
Abstract Genetic linkage maps are critical and indispensable tools in a wide range of genetic genomic research. With the advancement genotyping-by-sequencing (GBS) methods, construction high-density high-resolution has become achievable marine organisms lacking sufficient resources, such as echinoderms. In this study, high-density, map was constructed for sea cucumber species, Apostichopus japonicus , utilizing 2b-restriction site-associated DNA (2b-RAD) method. A total 7839 markers were...
Lipid nanoparticles (LNPs)-based messenger RNA (mRNA) therapeutics have emerged with promising potentials in the fields of infectious diseases, cancer vaccines, and protein replacement therapies; however, their therapeutic efficacy safety can still be promoted by optimization LNPs formulations. Unfortunately, current suffer from increased production reactive oxygen species during translation, which leads to a decreased translation efficiency onset inflammation other side effects. Herein, we...
The laser-induced hybrid hardening process integrates laser quenching and electromagnetic induction heating to overcome traditional heat treatment limitations, enhancing the depth properties of hardened layers for applications like wind turbine bearings. This study uses Box–Behnken design (BBD) experiments analyze key parameters develops response surface methodology (RSM) whale-optimization-algorithm-optimized back-propagation neural network (WOA-BPNN) models prediction optimization....
Cu<sup>2+</sup> and Fe<sup>3+</sup> can react with H<sub>2</sub>O<sub>2</sub>, producing Cu<sup>+</sup>, Fe<sup>2+</sup>, ˙OH. Then ˙OH phenol directly. The degradation of leads to the formation mixed byproducts, such as catechol, benzoquinone, resorcinol hydroquinone.
Neuropeptides play essential roles in regulation of reproduction and growth marine molluscs. But their function bivalves - a group animals commercial importance is largely unexplored due to the lack systematic identification these molecules. In this study, we sequenced analyzed transcriptome nerve ganglia Yesso scallop Patinopecten yessoensis, from which 63 neuropeptide genes were identified based on BLAST de novo prediction approaches, 31 confirmed by proteomic analysis using liquid...
It is of vital importance to understand the population structure, dissect genetic bases performance traits, and make proper strategies for selection in breeding programs. However, there no single webserver covering specific needs aquaculture. We present Aquaculture Molecular Breeding Platform (AMBP), first web server data analysis aquatic species farming interest. AMBP integrates haplotype reference panels 18 aquaculture species, which greatly improves accuracy genotype imputation. also...
In this paper, we focus on the long time behavior of mild solution to delayed reaction-diffusion Hopfield neural networks (DRDHNNs) driven by infinite dimensional Wiener processes. We analyze existence, uniqueness, and stability system under local Lipschitz function constructing an appropriate Lyapunov-Krasovskii utilizing semigroup theory. Some easy-to-test criteria affecting well-posedness networks, such as noise diffusion effect, are obtained. The can be used theoretic guidance stabilize...
This brief investigates nonautonomous stochastic reaction-diffusion neural-network models with S-type distributed delays. First, the existence and uniqueness of mild solution are studied under Lipschitz condition without linear growth condition. Due to a term infinite dimensional Wiener process, criteria for well-posedness established based on evolution system theory. Then, delay, which is an handled by truncation method, sufficient conditions global exponential stability obtained...