- Renal and related cancers
- Head and Neck Cancer Studies
- Pluripotent Stem Cells Research
- Cancer-related molecular mechanisms research
- Lymphoma Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Hepatitis B Virus Studies
- Electrospun Nanofibers in Biomedical Applications
- CRISPR and Genetic Engineering
- Circular RNAs in diseases
- Renal cell carcinoma treatment
- Organ Donation and Transplantation
- Glioma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Melanoma and MAPK Pathways
- Cancer-related Molecular Pathways
- 3D Printing in Biomedical Research
- Genetic and Kidney Cyst Diseases
- Computational Drug Discovery Methods
- Cell Adhesion Molecules Research
- Autophagy in Disease and Therapy
- Angiogenesis and VEGF in Cancer
- Polymer Surface Interaction Studies
- Lung Cancer Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
Zhongnan Hospital of Wuhan University
2020-2025
Wuhan University
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Chinese Academy of Fishery Sciences
2022-2024
Nanyang Technological University
2011-2024
Union Hospital
2015-2024
Massachusetts General Hospital
2024
West China Medical Center of Sichuan University
2024
Huazhong University of Science and Technology
2022-2024
Jiujiang First People's Hospital
2024
Liquid crystal monomers (LCMs) are a large family of artificial ingredients that have been widely used in global liquid display (LCD) industries. As major constituent LCDs as well the end products e-waste dismantling, LCMs growing research interest with regard to their environmental occurrences and biochemical consequences. Many studies analyzed multiple matrices, yet limited has investigated toxic effects upon exposure them. In this study, we combined silico simulation vitro assay...
// Wenkang Luan 1, * , Lubo Li 2, Yan Shi 4, Xuefeng Bu 3 Yun Xia 1 Jinlong Wang Henry Siaw Djangmah Xiaohui Liu Yongping You 5 Bin Xu Department of Plastic Surgery, Affiliated People's Hospital Jiangsu University, Zhenjiang, Jiangsu, China 2 Neurosurgery, General 4 Nanjing First Hospital, Medical Nanjing, The These authors have contributed equally to this work Correspondence to: Luan, email: luanwenkang@126.com Xu, xubinfen@126.com Keywords: MALAT1, miR-22, MMP14 and Snail, ceRNA, melanoma...
Abstract Antimicrobial resistance (AMR) is a pressing issue in China, with antibiotic therapy becoming less effective against bacterial infections. To address this challenge, the China Surveillance Network (CHINET) was established 2005 to monitor antimicrobial country. This study analyzed CHINET data from teaching hospitals and evaluated trends of AMR 2018 2022. A range 163,636 301,917 isolates obtained per year, majority being Gram-negative bacilli (69.0% 71.8%). The proportion important...
Microglia pyroptosis-mediated neuroinflammation is thought to be the crucial pathogenesis of sepsis-associated encephalopathy (SAE). Erbin has been reported associated with various inflammatory diseases. However, role in SAE and relationship between microglia pyroptosis are unknown. In this study, we investigated promising underlying molecular mechanism regulation pyroptosis.WT knockout mice underwent cecum ligation perforation (CLP) induce SAE. Primary mouse BV2 cells were treated...
Abstract Glioma tumour-initiating cells (GTICs) can originate upon the transformation of neural progenitor (NPCs). Studies on GTICs have focused primary tumours from which could be isolated and use human embryonic material. Recently, somatic genomic landscape gliomas has been reported. RTK (receptor tyrosine kinase) p53 signalling were found dysregulated in ∼90% 86% all analysed, respectively. Here we report human-induced pluripotent stem (hiPSCs) for modelling gliomagenesis. Dysregulation...
// Wenkang Luan 1, * , Rubo Li 2, Liang Liu 3, Xin Ni 4, Yan Shi 3 Yun Xia 1 Jinlong Wang Feng Lu and Bin Xu Department of Plastic Surgery, Affiliated People's Hospital Jiangsu University, Zhenjiang, China 2 Neurosurgery, Nanjing First Hospital, Medical Nanjing, 4 Gastroenterology, These authors have contributed equally to this work Correspondence to: Luan, email: luanwenkang@126.com Xu, xubinfen@126.com Keywords: malignant melanoma, ceRNA, HOTAIR, miR-152-3p, c-MET Received: April 15,...
Identifying phosphatase substrates: A peptide microarray has been developed for the high-throughput study of Ser/Thr phosphatases. Putative substrates, upon immobilization onto a glass slide, could be used to obtain kinetic information and identify substrate preferences (see schematic representation); with this information, new biology enzyme discovered. Supporting article is available on WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z703473_s.pdf or from author. Please note: The...
An increasing number of microRNAs have been found to be involved in tumorigenesis, including melanoma tumorigenesis. miR-204-5p is down-regulated and functions as a tumor suppressor many human malignant tumors. expression also decreased tissues, but its biological roles molecular mechanisms remain unclear. In this study, the aberrant down-regulation was detected melanoma, especially metastatic melanoma. served protective factor for prognosis patients. We determined that suppresses cell...