- Mesenchymal stem cell research
- Pluripotent Stem Cells Research
- Renal and related cancers
- TGF-β signaling in diseases
- Epigenetics and DNA Methylation
- Osteoarthritis Treatment and Mechanisms
- Hedgehog Signaling Pathway Studies
- Ion channel regulation and function
- Ion Channels and Receptors
- Genomics and Chromatin Dynamics
- Angiogenesis and VEGF in Cancer
- Plant Pathogens and Fungal Diseases
- Cell death mechanisms and regulation
- Neurobiology and Insect Physiology Research
- Acne and Rosacea Treatments and Effects
- Neuroscience and Neural Engineering
- RNA and protein synthesis mechanisms
- Biomedical Ethics and Regulation
- Antioxidant Activity and Oxidative Stress
- Congenital heart defects research
- PARP inhibition in cancer therapy
- Fungal Infections and Studies
- Immune cells in cancer
- Kruppel-like factors research
- Bioactive Compounds and Antitumor Agents
Second Affiliated Hospital of Xi'an Jiaotong University
2021-2024
Nanfang Hospital
2022
Southern Medical University
2022
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2017-2021
Chinese Institute for Brain Research
2021
Shanghai Institutes for Biological Sciences
2006-2016
Chinese Academy of Sciences
2006-2016
Salk Institute for Biological Studies
2012-2013
State Key Laboratory of Neuroscience
2009
Activation of SHH pathway contributes to glutamate toxicity, and inhibition SMO reduces ischemic brain damage in mice monkeys.
Abstract Neuronal excitability can cooperate with synaptic transmission to control the information storage. This regulation of neuronal plasticity be affected by alterations in inputs and accomplished modulation voltage‐dependent ion channels. In this study, we report that enhanced excitatory input negatively regulated excitability. Enhanced glutamate, electric field stimulation or high K + increased transient outward current, whereas did not affect delayed rectifier current rat cultured...
Dissecting cellulitis of the scalp (DCS) has a significant impact on physical well-being and body image patient. Since DCS often responds poorly to conventional treatments, there is need identify alternative treatment strategies. This study aimed explore effectiveness 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating DCS. Twelve male patients with treated solely ALA-PDT between June 2022 2023 at our institution were enrolled this study. Two underwent biopsy before after for...
To explore the effect of transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1) on toluene diisocyanate (TDI)-induced allergic airway inflammation in mice.Thirty-two mice were randomly divided into AOO group, AOO+5Z-7-Oxozeaenol TDI and TDI+5Z-7-Oxozeaenol group. Another 32 +5Z-7-Oxozeaenol + Necrostatin-1 TAK1 inhibitor (5Z-7-Oxozeaenol, 5 mg/kg) and/or RIPK1 (Necrostatin-1, used before each challenge. Airway responsiveness, remodeling assessed after treatments. We also examined...