A5001679038- Liver Disease Diagnosis and Treatment
- Uterine Myomas and Treatments
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Cancer-related molecular mechanisms research
- Liver Disease and Transplantation
- Pregnancy and Medication Impact
- RNA modifications and cancer
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Peptidase Inhibition and Analysis
- Ultrasound Imaging and Elastography
- Hepatitis Viruses Studies and Epidemiology
- Pregnancy-related medical research
- Maternal and fetal healthcare
- Immune cells in cancer
- Ferroptosis and cancer prognosis
- Gout, Hyperuricemia, Uric Acid
- Hepatitis B Virus Studies
- Ovarian function and disorders
- Gynecological conditions and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer Mechanisms and Therapy
- COVID-19 and healthcare impacts
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
The First People's Hospital of Shunde
2021-2025
Southern Medical University
2021-2025
The 180th Hospital of PLA
2018-2023
Wuhan University
2019-2023
Renmin Hospital of Wuhan University
2019-2023
Guangzhou University
2023
Nanfang Hospital
2022
Chinese People's Liberation Army
2022
ORCID
2021
Peking University
2020
Abstract We present 2 cases of coronavirus disease 2019 (COVID-19)–associated severe respiratory syndrome (SARS-CoV-2) infection during the third trimester pregnancy. Both mothers and newborns had excellent outcomes. failed to identify SARS-CoV-2 in all products conception newborns. This report provided evidence low risk intrauterine by vertical transmission SARS-CoV-2.
Abstract Background Chemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular mechanism human umbilical cord mesenchymal stem cell-derived exosomes (hUMSC-Exos) in function protection after chemotherapy. Methods hUMSC-Exos were applied cyclophosphamide-induced mice granulosa tumor cells (KGN) determine their effects on follicular development cell apoptosis. Evaluation was done for iron ion reactive oxygen...
To identify circRNA expression profiles in the placentae of severe preeclampsia (SPE) and normal pregnant (NP) women.Placental samples were collected from six paired SPE NP women. CircRNA identified by RNA-Seq validated another 30 qRT-PCR. Several bioinformatic tools utilised to analyse potential function differentially expressed circRNAs (DE-circRNAs) predict target microRNAs (miRNAs) proteins. Furthermore, immunohistochemistry, Western blotting RNA binding protein immunoprecipitation (RIP)...
Abstract We explored a new artificial intelligence-assisted method to assist junior ultrasonographers in improving the diagnostic performance of uterine fibroids and further compared it with senior confirm effectiveness feasibility intelligence method. In this retrospective study, we collected total 3870 ultrasound images from 667 patients mean age 42.45 years ± 6.23 [SD] for those who received pathologically confirmed diagnosis 570 women 39.24 5.32 without lesions Shunde Hospital Southern...
Levonorgestrel has been utilized in emergency contraception (EC) and for endometrial conditions. While abnormal uterine bleeding is a recognized adverse event (AE), other potential AEs remain undocumented. Safety data levonorgestrel were acquired from the United States FDA Adverse Event Reporting System (FAERS) database, covering period first quarter (Q1) of 2004 to fourth (Q4) 2023. A disproportionality analysis was conducted assess association between AEs. total 136,168 associated with...
There is limited concrete evidence connecting serum uric acid levels to female infertility. Therefore, this study aimed find out if are independently related infertility.From the National Health and Nutrition Examination Survey (NHANES) 2013-2020, a total sample of 5872 chosen participants between ages 18 49 were identified for cross-sectional study. The (mg/dL) each participant tested, reproductive health questionnaire was used evaluate subject's status. Both in analyses full subgroup,...
Image outpainting aims to generate the content of an input sub-image beyond its original boundaries. It is important task in generation yet remains open problem for generative models. This paper pushes technical frontier image two directions that have not been resolved literature: 1) with arbitrary and continuous multiples (without restriction), 2) a single step (even large expansion multiples). Moreover, we develop method does depend on pre-trained backbone network, which contrast commonly...
As a noninvasive marker, serum alanine aminotransferase (ALT) has limitations, because large proportion of patients chronically infected with hepatitis B virus (HBV) suffer from severe hepatic necroinflammation, but have normal or mildly elevated ALT. In the present study, we aimed to investigate potential value Golgi protein 73 (GP73) in predicting significant necroinflamation among chronic HBV patients. A cohort 497 was retrospectively recruited. Liver biopsy performed all and GP73 levels...
C3AR1 was reported in driving tumor immunity multiple cancers. However, its roles ovarian cancer remain unclear. This study aims to determine role of prognosis and regulating infiltrating immune cells (OC).The expression, clinical data related were collected from public databases such as The Cancer Genome Atlas (TCGA), Human Protein (HPA) Clinical Proteomics Tumor Analysis Alliance (CPTAC), further analyze their relationship with infiltration. Immunohistochemistry verified the expression...
Abstract Background Previous studies have shown the interaction between age and socioeconomic status (SES) on risk of infertility in UK, but association is still unclear United States. Therefore, present study investigated effect relationship SES American women. Methods The included adults who participated National Health Nutrition Examination Survey (NHANES) from 2013 to 2018. poverty income ratio (PIR) was used represent population. With participants stratified according category (< 35...
Bioinformatics analysis indicated that the arrestin ARRDC3 was upregulated in placental tissue from patients with preeclampsia (PE). The study aimed to confirm finding by examining placenta samples women and without early-onset PE investigate roles trophoblast function. expression level localization were determined Western blot, real-time quantitative PCR immunohistochemistry. An vitro hypoxia an ischemia (hypoxia/reoxygenation) cell models used determine hypoxic ischemic effects on...
In this paper, we describe our ensemble-based system designed by guoym Team for the SemEval-2020 Task 8, Memotion Analysis. system, utilize five types of representation data as input base classifiers to extract information from different aspects. We train each type using five-fold cross-validation. Then outputs these are combined through data-based ensemble method and feature-based make full use all representations Our achieves performance within top 2 ranks in final leaderboard Analysis...
This study investigates the intricate role of Heme Oxygenase 1 (HMOX1) in ovarian cancer, emphasizing its prognostic significance, influence on immune cell infiltration, and impact malignant characteristics primary cancer cells.
The uncoupling proteins (UCPs) are critical genes associated with tumorigenesis and chemoresistance. However, little is known about the molecular mechanism of UCPs in ovarian cancer (OV).UCPs expression analysis was conducted using Gene Expression Profiling Interactive Analysis (GEPIA), its potential clinical prognosis analyzed Kaplan- Meier analyses. influence on immune infiltration by TIMER. In addition, correlation between mechanisms investigated TIMER Cancer Single-cell State Atlas...
Introduction: Trophoblast plays a vital role in the embryonic implantation and function of placenta. Exposure to hyperglycemic environment results abnormal trophoblasts during fetoplacental development, which leads maternal complications poor fetal outcomes. However, precise mechanisms placental pathology hyperglycemia remain elusive. We investigated CYP1B1 functional behavior extravillous trophoblast (EVT) cell line HTR-8/SVneo under condition.Methods: determined expression via real-time...
Acute-on-chronic liver failure (ACLF) is the abrupt exacerbation of declined hepatic function in patients with chronic disease.To explore independent predictors short-term prognosis hepatitis B virus (HBV)-related ACLF and to establish a predictive model for HBV-related ACLF.From January 2016 December 2019, 207 attending 910th Hospital Chinese People's Liberation Army were continuously included this retrospective study. Patients stratified based on their survival status 3 mo after diagnosis....
Prostaglandins participate in maternal recognition of pregnancy, implantation and maintenance gestation. Prostaglandin transporter (PGT), as a candidate molecule prostaglandin carriers, might be involved the pathogenesis preeclampsia. In preeclampsia (PE) patients' placental tissue, we identified PGT by RNA sequencing, measured its expression pattern quantitative real-time PCR Western blot. was found to upregulated preeclamptic tissue. The PE double confirmed eight Gene Expression Omnibus...
To determine immunohistochemical features and correlations between M1/M2 polarisation status with disease severity of post-caesarean scar diverticulum (CSD).Histological immunohistological stainings were performed inflammatory (CD16, CD163 tumour necrosis factor-α (TNF-α)), fibrosis (α-smooth muscle actin (α-SMA)) angiogenic (CD31) markers examined in uterine tissues collected from patients diverticula (CSD) (n=37) caesarean section (CS) (n=3).CSD have higher expression α-SMA, TNF-α, CD16...
Microwave ablation (MWA) is an effective treatment option for patients with primary liver cancer. However, it has been reported that the MWA procedure induces a hepatic inflammatory response and injury, which may negatively affect efficacy of MWA. As such, discovery reliable markers to monitor patient's needed. Golgi protein 73 (GP73) shown be associated chronic disease. To date, potential value serum GP73 in dynamic monitoring during cancer remains unclear.To examine effects on levels...