A5108063842- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Epilepsy research and treatment
- HER2/EGFR in Cancer Research
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Radiopharmaceutical Chemistry and Applications
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- X-ray Diffraction in Crystallography
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Neurological Disease Mechanisms and Treatments
- Advanced Radiotherapy Techniques
- Neuroscience and Neuropharmacology Research
- Vascular Malformations Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Radiation Dose and Imaging
Huashan Hospital
2016-2025
Fudan University
2016-2025
Qingdao University
2022-2025
Affiliated Hospital of Qingdao University
2022-2025
Southwest Medical University
2025
Affiliated Hospital of Zunyi Medical College
2011-2025
Peking University International Hospital
2023-2024
Tsinghua University
2024
Dazhou Central Hospital
2021-2024
Linyi People's Hospital
2024
We report the quantum transport properties of Cd₃As₂ single crystals in a magnetic field. A large linear magnetoresistance is observed near room temperature. With decreasing temperature, Shubnikov-de Haas oscillations appear both longitudinal resistance R(xx) and transverse Hall R(xy). From strong oscillatory component ΔR(xx), dependence Landau index n on 1/B obtained, it gives an n-axis intercept between 1/2 5/8. This clearly reveals nontrivial π Berry's phase, which distinguished feature...
Abstract Objectives To compare the effectiveness and safety between autologous platelet‐rich plasma ( PRP ) Local Anesthetic (LA) /corticosteroid in intra‐articular injection for treatment of lumbar facet joint syndrome. Methods Forty‐six eligible patients with syndrome were randomized into group A (intra‐articular B LA /corticosteroid). The following contents evaluated: pain visual analog scale VAS at rest during flexion, Roland‐Morris Disability Questionnaire RMQ ), Oswestry Index ODI...
Thrombolysis has been a standard treatment for ischemic stroke. However, only 2-7% patients benefit from it because the thrombolytic agent to be injected within 4.5 h after onset of symptoms avoid increasing risk intracerebral hemorrhage. As clinically approved neuroprotective drug, edaravone (EDV) rescues brain tissues by eradicating over-produced reactive oxygen species (ROS) without limitation therapeutic time-window. EDV's short circulation half-life and inadequate cerebral uptake...
Abstract Background The tumor immune microenvironment can influence the prognosis and treatment response to immunotherapy. We aimed develop a non-invasive radiomic signature in high-grade glioma (HGG) predict absolute density of tumor-associated macrophages (TAMs), preponderant cells HGG. also evaluate association between signature, phenotype as well Methods In this retrospective setting, total 379 patients with HGG from three independent cohorts were included construct model named Radiomics...
Due to low success rates and long cycles of traditional drug development, the clinical tendency is apply omics techniques reveal patient-level disease characteristics individualized responses treatment. However, heterogeneous form data uneven distribution targets make discovery precision medicine a non-trivial task. This study takes pyroptosis therapy for triple-negative breast cancer (TNBC) as paradigm uses mining large TNBC cohort databases establish biofactor-regulated neural network...
This pilot study explores the potential of noninvasive diffuse correlation spectroscopy (DCS) and reflectance (DRS) for monitoring early relative blood flow (rBF), tissue oxygen saturation (StO2), total hemoglobin concentration (THC) responses to chemo-radiation therapy in patients with head neck tumors. rBF, StO2, THC superficial tumor nodes eight are measured before during period. The weekly kinetics exhibit different patterns individuals, including significant changes first two weeks....
Objective: To determine whether the cystatin C gene (CST3) is genetically associated with late-onset Alzheimer disease (AD).Design: A case-control study 2 independent populations of patients AD and age-matched, cognitively normal control subjects.
The air route network, which supports all the flight activities of civil aviation, is most fundamental infrastructure traffic management system. In this paper, we study Chinese network (CARN) within framework complex networks. We find that CARN a geographical possessing exponential degree distribution, low clustering coefficient, large shortest path length and spatial distance distribution obviously different from airport (CAN). Besides, via investigating data 2002 to 2010, demonstrate...
Glioblastoma multiforme (GBM) is an aggressive primary brain tumor with dismal survival. This study aims to examine the prognostic value of sites and race on survival outcomes.Patient data obtained from Scott White Hospital Brain Tumor Registry (1976-2013) were stratified according sex, age, race, site, vital status, survival.Of 645 patients, 580 (89.9%) diagnosed GBM not otherwise specified (GBM NOS), 57 (8.8%) GBM, 8 (1.2%) giant-cell GBM. Most male (53.5%), aged 50 years or older (78.7%)....
Topological Weyl semimetals (TWSs) with pairs of points and topologically protected Fermi arc states have broadened the classification topological phases provide superior platform for study superconductivity. Here we report nontrivial superconductivity features sulfur-doped Td -phase MoTe2 enhanced Tc compared type-II TWS It is found that S-doped (MoTe2-x S x , ∼ 0.2) a two-band s-wave bulk superconductor (∼0.13 meV 0.26 meV), where superconducting behavior can be explained by s+- pairing...
Generation of sulfonated isobenzofuran-1(3<italic>H</italic>)-ones starting from 2-vinylbenzoic acids, aryldiazonium tetrafluoroborates, and DABCO˙(SO<sub>2</sub>)<sub>2</sub> under photocatalysis in the presence visible light is achieved. Additionally, method can be extended to 4-phenylpent-4-enoic acid 5-phenylhex-5-enoic acid.
A copper(<sc>ii</sc>)-catalyzed aerobic oxidative reaction of arylhydrazines, DABCO·(SO<sub>2</sub>)<sub>2</sub> and alkenes is reported. Diverse β-hydroxysulfones are generated in moderate to good yields through the hydroxysulfonylation with insertion sulfur dioxide under mild conditions. In some cases, β-ketosulfones produced.
Abstract Approximately 50% of colorectal cancer (CRC) patients would develop metastasis with poor prognosis, therefore, it is necessary to effectively predict in clinical treatment. In this study, we aimed establish a machine-learning model for predicting CRC by considering radiomics and transcriptomics simultaneously. Here, 1023 from three centers were collected divided into five queues (Dazhou Central Hospital n = 517, Nanchong 120 the Cancer Genome Atlas (TCGA) 386). A total 854 features...
A four-component reaction of 2-vinylbenzoic acids, aryldiazonium tetrafluoroborates, the sulfur dioxide surrogate DABCO·(SO2)2, and nitriles under photocatalysis in presence visible light is developed. This multicomponent works efficiently, promoted by BF3·OEt2 with insertion mild conditions, leading to sulfonated 1-isoindolinones moderate good yields. route highly selective, several competitive pathways are not observed these conditions. possible mechanism involving a Lewis acid proposed.
2-Sulfonylanilines are generated in moderate to good yields through a three-component reaction of anilines, DABCO·(SO<sub>2</sub>)<sub>2</sub>, and aryldiazonium tetrafluoroborates under mild conditions. No metal catalysts or additives needed for this transformation.
Tumor microenvironment (TME)-specific nanocatalysts for augmented synergistic chemodrug and chemodynamic cancer therapy have been constructed, which feature an optimized effect on TME features. Systematic <italic>in vitro</italic> vivo</italic> tests revealed the high therapeutic activity of substantially suppressing tumor growth.