A5100602434- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Calpain Protease Function and Regulation
- Systemic Lupus Erythematosus Research
- Neurotransmitter Receptor Influence on Behavior
- Nerve injury and regeneration
- Complement system in diseases
Xizang Minzu University
2016-2019
Northwest University
2016
Toll-like receptors (TLRs) are a family of transmembrane receptors, and play vital role in recognizing invading pathogens activating innate immunity. Previous studies indicated that TLR1 single nucleotide polymorphisms (SNPs) might be associated with the risk IgA nephropathy (IgAN). This study aims to investigate relationship between SNPs (rs4833095 rs5743557) IgAN Chinese Han population. case-control included 351 patients 310 healthy controls. Two were genotyped by Sequenom MassARRAY. Odds...
The number of heroin addicts is increasing in the world. Both environmental and genetic factors both play critical roles process addiction. We aimed to investigate associations between single nucleotide polymorphisms (SNPs) LIN7C, BDNFOS BDNF genes drug addiction Han Chinese population.We conducted a case-control study among 692 cases 700 healthy controls from Xi'an, China. Eight SNPs were selected genotyped using MassARRAY technology (Sequenom, San Diego, CA, USA). Odds ratios (OR) 95%...
Abstract Background The biological mechanisms driving disease chronicity in rheumatoid arthritis (RA) are largely unidentified. Therefore, we aimed to determine genetic risk factors for RA. Methods In this case–control study, which includes samples from 499 patients and 507 healthy controls, six single‐nucleotide polymorphisms (SNPs) interleukin‐2 receptor subunit alpha ( IL2RA ) IL2RB were selected. Genotyping was performed using the Agena MassARRAY platform, statistical analyses...