- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Cardiac and Coronary Surgery Techniques
- Cholesterol and Lipid Metabolism
- Ultrasound in Clinical Applications
- Shoulder and Clavicle Injuries
- Adipokines, Inflammation, and Metabolic Diseases
- Shoulder Injury and Treatment
- Coronary Interventions and Diagnostics
- Cardiovascular Disease and Adiposity
- Inflammasome and immune disorders
- Kawasaki Disease and Coronary Complications
- Cardiac tumors and thrombi
- Advanced MRI Techniques and Applications
- Eosinophilic Disorders and Syndromes
- Aortic Disease and Treatment Approaches
University Hospital Bonn
2012-2025
University of Bonn
2012-2013
This study investigated the clinical outcomes of transcatheter edge-to-edge repair for atrial functional mitral regurgitation and found links between degree residual regurgitation, mean valve pressure gradient, outcomes.
Abstract Aims Prognostic impact of post‐procedural changes in right ventricular (RV) function after tricuspid transcatheter edge‐to‐edge repair (T‐TEER) is still unclear. We investigated association RV and its with clinical outcomes patients undergoing T‐TEER. Methods results retrospectively analysed 204 who underwent T‐TEER echocardiographic follow‐up at 3 months was assessed by fractional area change (RVFAC), dysfunction defined as RVFAC <35%. Patients an increase from baseline to the...
A mismatch between tricuspid leaflet size and annular dilation is one of the morphological features tied to development regurgitation (TR).We assessed association leaflet-to-annulus index (LAI) with residual TR after transcatheter edge-to-edge repair (TEER).Consecutive patients who underwent TEER for were enrolled. Significant was defined as a post-procedural ≥3+, divided into two groups according amount TR. The LAI retrospectively calculated using procedural transoesophageal...
Abstract Aims The role of right ventricular function in patients undergoing transcatheter tricuspid valve repair (TTVR) is poorly understood. This study investigated the association ejection fraction (RVEF) assessed by cardiac computed tomography (CCT) with clinical outcomes TTVR. Methods and results We retrospectively three-dimensional (3D) RVEF using pre-procedural CCT images RV dysfunction was defined as a CT-RVEF &lt;45%. primary outcome composite outcome, consisting all-cause...
BACKGROUND: We assessed the safety profile of tricuspid transcatheter edge-to-edge repair (TEER) in patients with right ventricular (RV) dysfunction. METHODS: identified undergoing TEER to treat regurgitation from June 2015 October 2021 and annular plane systolic excursion (TAPSE) RV fractional area change (RVFAC). dysfunction was defined as TAPSE <17 mm RVFAC <35%. The primary end point 30-day mortality after TEER. also investigated function early phase clinical outcomes at 2 years....
Abstract Background Transcatheter tricuspid valve repair (TTVR) is a promising technique for the treatment of regurgitation (TR). Data comparing performance novel edge-to-edge devices (PASCAL and MitraClip-XTR) are scarce. Methods We identified 80 consecutive patients who underwent TTVR using either PASCAL or MitraClip-XTR system to treat symptomatic TR from July 2018 June 2020. To adjust baseline imbalances, we performed propensity score (PS) 1:1 matching. The primary endpoint was reduction...
Abstract To explore the feasibility of CT-derived myocardial strain measurement in patients with advanced cardiac valve disease and to compare it measurements derived from transthoracic echocardiography (TTE). 43 consecutive clinically indicated retrospectively gated CTs were analyzed. The longitudinal, circumferential as well radial systolic determined all utilizing a commercially available CT software. In 36/43 (84%) patients, longitudinal was compared speckle-tracking TTE. Pearson’s...
Abstract Background Transcatheter mitral valve replacement (TMVR) has emerged as alternative to transcatheter edge-to-edge repair (TEER) for treatment of regurgitation (MR); however, the role TMVR with Tendyne system among established treatments MR is not well defined. We assessed characteristics and outcomes patients treated in current clinical practice. Methods reviewed who underwent cardiac computed tomography were judged eligible system. Results A total 63 Of these, 17 TMVR, 46 by TEER....
Abstract Background Obesity and underweight represent classical risk factors for outcome in patients treated cardiovascular disease. This study describes the impact of different body mass index (BMI) categories on 1-year clinical with tricuspid regurgitation (TR) undergoing transcatheter-edge-to-edge repair (TEER). Methods We analyzed 211 consecutive (age 78.3 ± 7.2 years, 55.5% female, median EuroSCORE II 9.6 6.7) TEER from June 2015 until May 2021. Patients were prospectively enrolled our...
Abstract Hepatorenal dysfunction is a strong risk factor in patients with heart failure (HF). We investigated the prognostic significance of hepatorenal 172 consecutive undergoing transcatheter tricuspid valve repair (TTVR). The model for end-stage liver disease excluding international normalized ratio (MELD-XI) score was calculated as 5.11 × ln(serum total bilirubin [mg/dl]) + 11.76 creatinine 9.44. Patients were stratified into two groups: high (≥ 14) or low (< MELD-XI score, according...
It remains unclear what proportion of patients with tricuspid regurgitation (TR) are suitable candidates for transcatheter valve intervention (TTVI) in clinical practice.
To investigate the rate and clinical impact of a persisting iatrogenic atrial septal defect (iASD) after percutaneous left appendage occlusion (LAAO).Percutaneous LAAO is an alternative to oral anticoagulation (OAC) for prevention ischemic stroke systemic embolism in patients with fibrillation (AF). Data regarding incidence persistence iASD procedures its relevance scarce.We retrospectively analyzed 144 that underwent at our center between 2009 2020 who had least one follow-up including...