A5020041586- Cerebral Palsy and Movement Disorders
- Stroke Rehabilitation and Recovery
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Neural dynamics and brain function
- Spinal Cord Injury Research
- Botulinum Toxin and Related Neurological Disorders
- Non-Invasive Vital Sign Monitoring
- Fetal and Pediatric Neurological Disorders
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Autism Spectrum Disorder Research
- Anatomy and Medical Technology
- Prosthetics and Rehabilitation Robotics
- Children's Physical and Motor Development
- Advanced Memory and Neural Computing
- 3D Printing in Biomedical Research
- Genetic Neurodegenerative Diseases
- Vestibular and auditory disorders
- Heart Rate Variability and Autonomic Control
- Balance, Gait, and Falls Prevention
- Assistive Technology in Communication and Mobility
- Action Observation and Synchronization
- Traumatic Brain Injury Research
- Family and Disability Support Research
IRCCS Eugenio Medea
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Politecnico di Milano
2008-2016
Italian Institute of Technology
2014
It is known that cell density influences the maturation process of in vitro neuronal networks. Neuronal cultures plated with different densities differ number synapses per neuron and thus single synaptic transmission, which results a density-dependent network activity. Although many authors provided detailed information about effects on culture activity, dedicated report age influence hippocampal activity has not yet been reported. Therefore, this work aims at providing reference data to...
<title>Abstract</title> <bold>Background:</bold> Spinal cord injury (SCI) severely affects physical function, leading to muscle atrophy and reduced bone density. Sport-therapy, incorporating recreational competitive activities, has shown promise in enhancing recovery for individuals with SCI. Functional Electrical Stimulation (FES)-cycling combines exercise benefits stimulation advantages, recent integration mobile recumbent trikes adds further potential. This study aimed evaluate the...
Summary Background: Acquired brain injury (ABI) may result in lifelong impairment of physical, cognitive, and psychosocial functions. Several rehabilitative treatments are often needed to support walking recovery, thus participants’ engagement becomes a crucial aspect, especially when patients children. In the last few years, traditional physiotherapy (PT) has been flanked by innovative technologies for rehabilitation fields robotics Virtual Reality (VR). Preliminary results have shown...
Objective . The minimum clinically important difference (MCID) is a standard way of measuring clinical relevance. objective this work was to establish the MCID for 6-minute walking test (6minWT) and Gross Motor Function Measure (GMFM-88) in pediatric gait disorders. Methods A cohort, pretest-posttest study conducted hospitalized care setting. total 182 patients with acquired brain injury (ABI) or cerebral palsy (CP) performed 20 robot-assisted training sessions complemented physical therapy...
Breathing frequency (fB) is an important vital sign that-if appropriately monitored-may help to predict clinical adverse events. Inertial sensors open the door development of low-cost, wearable, and easy-to-use breathing-monitoring systems. The present paper proposes a new posture-independent processing algorithm for breath-by-breath extraction breathing temporal parameters from chest-wall inclination change signals measured using inertial measurement units. An step dimension reduction (DR)...
Abstract In recent years, 3D printing gained considerable attention in the orthopedic sector. This work evaluates feasibility of producing scoliosis braces by printing, comparing performance and costs with classical thermoforming procedures. Critical parameters, such as manufacture time, mechanical properties, weight, comfort are carefully considered. Polyethylene terephthalate glycol-modified (PETG) was selected among several filaments materials present on market. Printed samples were...
BACKGROUND: Robot-Assisted Gait Training (RAGT) is a widespread approach for locomotion rehabilitation but information about intervention frequency and duration still lacking. OBJECTIVE: To evaluate the effect of RAGT on motor outcome children affected by Cerebral Palsy (CP). METHODS: Forty-four CP (age 4–17) underwent one among four different intensive trainings with equal dose intervention, combining Task-Oriented Physiotherapy (TOP) RAGT: 40 sessions (4 sessions/week) over 10 weeks sole...
<sec> <title>BACKGROUND</title> COVID-19 pandemic increased the need to develop long-term remote rehabilitative programs. Most existing telerehabilitation platforms focus on rehabilitating upper limbs, balance, and cognitive training, but exercises improving cardiovascular fitness are often neglected. </sec> <title>OBJECTIVE</title> To evaluate acceptability feasibility of a intervention combining aerobic exercises. <title>METHODS</title> A virtual reality-based dual-task exercise exploiting...
<title>Abstract</title> <bold>Background:</bold> Spinal cord injury (SCI) severely affects physical function, leading to muscle atrophy and reduced bone density. Sport-therapy, incorporating recreational competitive activities, has shown promise in enhancing recovery for individuals with SCI. Functional Electrical Stimulation (FES)-cycling combines exercise benefits stimulation advantages, recent integration mobile recumbent trikes adds further potential. This study aimed evaluate the...
Spinal cord injury (SCI) severely affects physical function, leading to muscle atrophy and reduced bone density. Sport-therapy, incorporating recreational competitive activities, has shown promise in enhancing recovery for individuals with SCI. Functional Electrical Stimulation (FES)-cycling combines exercise benefits stimulation advantages, recent integration mobile recumbent trikes adds further potential. This study aimed evaluate the effects of a 6-month FES-cycling sport therapy using...
Congenital Central Hypoventilation Syndrome (CCHS) is a rare disorder that impairs autonomic breathing control, leading to alveolar hypoventilation and sometimes central apnoea, predominantly during sleep. Patients typically require nocturnal ventilatory support alarms prevent life-threatening desaturation events. However, current alarm systems integrated into pulse oximeters do not provide adequate assistance at home. To address these limitations, we developed an assistive device with...
Functional near-infrared spectroscopy (fNIRS) is particularly suitable for measuring brain activity during motor tasks, due to its portability and good motion tolerance. In such cases, the trials’ duration may vary depending on experimental conditions or participant’s response, therefore a comparison of hemodynamic responses across repetitions cannot be properly performed. this work, we present MATLAB (R2023a) function (TaskNorm.m) developed time-normalizing fNIRS data recorded trials with...
Abstract Traditional average-based metrics have long been considered the gold standard in behavioral and brain research. However, recent advances emphasize importance of examining dispersion around mean to uncover nuances individual differences challenge simplistic assumptions. Thus, study variability is becoming increasingly central across a wide range domains. Here, we tackle composite architecture motor by proposing new geometric method model it. Three independent gait datasets are used...
Functional Electrical Stimulation Assisted Cycling (FES-cycling) is a rehabilitation intervention for individuals with Spinal Cord Injury (SCI), offering benefits like increased muscle trophism, improved cardiopulmonary function, and reduced bone demineralization. Despite numerous studies on its physical advantages, few have focused user experience. This study evaluates the experience, usability, acceptability, human-device interaction of two FES-cycling systems: recumbent FES-bike prototype...
Quantitative evaluation of gait has been considered a useful tool with which to identify subtle signs motor system peculiarities in autism spectrum disorder (ASD). However, there is paucity studies reporting data ASD as well investigating learning processes locomotor activity. Novel advanced technologies that couple treadmills virtual reality environments and motion capture systems allows the patterns on multiple steps effects induced perturbations, ability manipulate visual proprioceptive...
Abstract The notion of “vitality form” has been coined by Daniel Stern to describe the basic features action, which may reflect mood or affective state an agent. There is general consensus that vitality forms substantiate social interactions in children as well adults. Previous studies have explored with Autism Spectrum Disorder (ASD)’s ability copying and recognizing actions performed others. In this paper we investigated, for first time, how ASD express different when acting themselves. We...
Virtual reality (VR) creates computer-generated virtual environments where users can experience and interact in a similar way as they would do real life. VR systems are increasingly being used for rehabilitation goals, mainly with adults, but also children, extending their application to the educational field. This report concerns study of impact semi-immersive system group 25 children kindergarten context. The were involved several different games activity types, specifically developed aim...
Abstract This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The is randomised controlled trial in which 28 aged 7–25 yo were randomly allocated to VR-Spirit or control intervention VR. required participants compete different avatars scenarios that prompted them form predictions about avatars’ intentions. consisted games currently adopted motor...
Abstract Background Spinal cord injuries (SCIs) cause debilitating secondary conditions such as severe muscle deterioration, cardiovascular, and metabolic dysfunctions, significantly impacting patients’ quality of life. Functional electrical stimulation (FES) combined with cycling exercise (FES-cycling) has shown promise in improving function health individuals SCI. Objective This pilot study aimed to investigate the potential role multiparametric magnetic resonance imaging (MRI) assess...