Claudia Rugeles

ORCID: 0000-0002-2573-1585
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About
Contact & Profiles
Research Areas
  • Immunodeficiency and Autoimmune Disorders
  • T-cell and B-cell Immunology
  • Blood disorders and treatments
  • Reproductive System and Pregnancy
  • Family and Patient Care in Intensive Care Units
  • Retinal Imaging and Analysis
  • Pregnancy and preeclampsia studies
  • Immune Cell Function and Interaction
  • HIV-related health complications and treatments
  • Cytokine Signaling Pathways and Interactions
  • Tracheal and airway disorders
  • HIV/AIDS Research and Interventions
  • Cystic Fibrosis Research Advances
  • HIV Research and Treatment
  • Maternal Mental Health During Pregnancy and Postpartum
  • Mycobacterium research and diagnosis
  • Cancer Immunotherapy and Biomarkers
  • Noise Effects and Management

Universidad de Antioquia
2001-2008

The human immunodeficiency virus type 1 (HIV-1) has tropism for the immune and central nervous systems (CNS). Intrauterine exposure to HIV-1 induces immunological alterations, independent of infection that might affect development CNS. Similarly, intrauterine antiretrovirals also neurodevelopment.To evaluate neurodevelopment babies born positive mothers (exposed) compare with negative (unexposed).We carried-out an observational prospective study 23 exposed 20 unexposed children using infant...

10.33588/rn.4806.2008400 article EN Revista de Neurología 2009-01-01

La infección recurrente es una causa frecuente de consulta médica y puede deberse a un grupo heterogéneo trastornos que incrementan la susceptibilidad los microorganismos patógenos oportunistas, como las deficiencias inmunológicas subyacentes.Con el fin definir tratamiento racional oportuno orientar diagnóstico molecular inmunodeficiencias primarias, se estableció programa para fenotípico estas enfermedades en departamento Antioquia (Colombia), comprende análisis clínico laboratorio...

10.7705/biomedica.v22i4.1177 article ES publisher-specific-oa Biomédica 2002-12-01

The incidence of maternal-to-fetal human immunodeficiency virus type 1 (HIV-1) transmission is 25-30% in absence antiretroviral therapy, and inversely associated with Human leukocyte antigens (HLA) class-I discordance. Based on our earlier report that mixed lymphocyte reactions (MLR) induce a ribonuclease (RNase) inhibits HIV-1 replication, we proposed maternal-fetal alloantigen stimulation activates factors protect the fetus against vertically- transmitted infections. We investigate here...

10.2174/157016208785132536 article EN Current HIV Research 2008-07-01

Introducción: El ruido es una de las principales causas preocupación para muchas poblaciones, ya que incide en la calidad vida y, además, puede provocar efectos nocivos sobre salud. Uno sus pérdida audición (hipoacusia), ser reversible o permanente, pues progresa con lentitud, forma proporcional exposición. Objetivos: Implementar un estudio monitorización los auditivos y no salud determinando niveles poblacional ambiental docentes localidades Fontibón Engativá, contribuya construcción del...

10.56085/20277970.70 article ES Investigaciones en Seguridad Social y Salud 2015-06-01

The hyper-IgE syndrome with recurrent infections (HIESRI) is characterized by skin and respiratory due to Staphylococcus aureus several fungi which are frequently associated tissue damage. A deficiency in the chemotaxis of phagocytic cells has been documented explain these findings; however, expression adhesion molecules, secretion cytokines that activate granulocytes production oxygen reactive molecules have not evaluated HIESRI. Six HIESRI patients were for following parameters: (1) GM-CSF...

10.7705/biomedica.v23i1.1198 article EN publisher-specific-oa Biomédica 2003-03-01

Several primary immunodeficiency diseases affecting the interleukin 12/interferon gamma (IFN-gamma) pathway have been identified, most of them characterized by recurrent and protracted infections produced intracellular microorganisms, particularly several species mycobacteria. In present study we analyzed expression IFN-gamma receptor (IFN-gammaR) signal transducer activator transcription 1 (STAT-1) in 4 children with Mycobacterium tuberculosis infection uncommon clinical presentation. These...

10.1590/s0100-879x2004000900010 article EN cc-by Brazilian Journal of Medical and Biological Research 2004-09-01
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