A5025937995- Enzyme Catalysis and Immobilization
- Chemical Synthesis and Analysis
- Amino Acid Enzymes and Metabolism
- Biochemical and Structural Characterization
- Microbial Metabolic Engineering and Bioproduction
- Advanced Photocatalysis Techniques
- Nanomaterials for catalytic reactions
- Biochemical and Molecular Research
- RNA and protein synthesis mechanisms
- Polyamine Metabolism and Applications
- Click Chemistry and Applications
- Glycosylation and Glycoproteins Research
- Peptidase Inhibition and Analysis
- Carbohydrate Chemistry and Synthesis
- Electrochemical sensors and biosensors
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced biosensing and bioanalysis techniques
Hangzhou Normal University
2021-2023
A chemo-enzymatic cascade was developed for the cyanide-free synthesis of nitriles from aldehydes and further one-pot transformation into amides.
Genetically encoded nonstandard amino acids (NSAAs) facilitate the covalent assembly of enzymes and enable their self-purification, enhanced activity stability.
Engineering of biological pathways with man-made materials provides inspiring blueprints for sustainable drug production. (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol [(R)-3,5-BTPE], as an important artificial chiral intermediate complicated pharmaceutical drugs and biologically active molecules, is often synthesized through a hydrogenation reaction 3,5-bis(trifluoromethyl)acetophenone (3,5-BTAP), in which enantioselectivity sufficient hydrogen are the key to restricting reaction. In this...
Ideal immobilization with enhanced biocatalyst activity and thermostability enables natural enzymes to serve as a powerful tool yield synthetically useful chemicals in industry. Such an enzymatic method strategy becomes easier more convenient the use of genetic protein engineering. Here, we developed covalent programmable polyproteam tyrosine ammonia lyases (TAL-CLEs) by fusing SpyTag SpyCatcher peptides into N-terminal C-terminal TAL, respectively. The resulting circular were clear after...
Correction for ‘Controlled chemical assembly of enzymes in cell lysate enabled by genetic-encoded nonstandard amino acids’ Jing Zhang et al. , Mater. Chem. Front. 2022, 6 182–193, https://doi.org/10.1039/D1QM01285A.