Defei Chen

ORCID: 0000-0002-2579-3866
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About
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Research Areas
  • Colorectal Cancer Surgical Treatments
  • Gastric Cancer Management and Outcomes
  • Stoma care and complications
  • Anorectal Disease Treatments and Outcomes
  • Metastasis and carcinoma case studies
  • Reservoir Engineering and Simulation Methods
  • Coal Properties and Utilization
  • Oil and Gas Production Techniques
  • Hydraulic Fracturing and Reservoir Analysis
  • Seismic Imaging and Inversion Techniques
  • Rock Mechanics and Modeling
  • Lymphoma Diagnosis and Treatment
  • Colorectal and Anal Carcinomas
  • Hydrocarbon exploration and reservoir analysis
  • Enhanced Recovery After Surgery
  • Sleep and related disorders
  • Drilling and Well Engineering
  • Viral-associated cancers and disorders
  • Gastrointestinal Tumor Research and Treatment
  • Ferroptosis and cancer prognosis
  • Nutritional Studies and Diet
  • Genetic Associations and Epidemiology
  • Dietary Effects on Health
  • Hernia repair and management
  • Gastroesophageal reflux and treatments

Chongqing Medical University
2022-2025

The Affiliated Yongchuan Hospital of Chongqing Medical University
2022-2025

Oil and Gas Center
2024

Chongqing Public Health Medical Center
2023

China National Petroleum Corporation (China)
2015-2021

Tarim University
2016-2021

To analyze the incidence and risk factors of postoperative fever (POF) in gastrointestinal cancer (GIC), discuss influence POF on short-term clinical outcomes, predict anastomotic leakage (AL) based characteristics. Overall, 1362 patients that underwent radical resection for GIC were retrospectively analyzed. was defined as a temperature ≥38°C during hospitalization. Patients divided according to whether they experienced POF. The outcomes analyzed using propensity score matching. A subgroup...

10.3389/fonc.2024.1413041 article EN cc-by Frontiers in Oncology 2025-01-10

Abstract Background Temporary ileostomy (TI) has proven effective in reducing the severity of anastomotic leakage after rectal cancer surgery; however, some ileostomies fail to reverse over time, leading conversion into a permanent stoma (PS). In this study, we aimed investigate preoperative risk factors and cumulative incidence TI non-closure sphincter-preserving surgery for cancer. Materials methods We conducted meta-analysis searching Embase, Web Science, PubMed, MEDLINE databases from...

10.1186/s12957-024-03363-z article EN cc-by World Journal of Surgical Oncology 2024-04-12

To improve perioperative frailty status in patients undergoing laparoscopic colorectal cancer surgery (LCCS), we explored a new intensive prehabilitation program that combines exercises with standard enhanced recovery after (ERAS) and its impact.

10.3389/fonc.2024.1411353 article EN cc-by Frontiers in Oncology 2024-09-12

Self-pulling and latter transection (SPLT) reconstruction has been applied in total laparoscopic gastrectomy BI (known as Delta SPLT) distal (TLDG) some previous studies. This approach can reduce the technical difficulty of surgery well quantity cartridges required, with manageable safety. Here, we used SPLT to complete Roux-en-Y TLDG evaluated safety effectiveness this novel method by comparing it conventional laparoscopy-assisted (LADG).Patients gastric cancer who underwent SPLT-TLDG or...

10.3389/fonc.2022.916692 article EN cc-by Frontiers in Oncology 2022-10-07

Background Laparoscopic right hemicolectomy is a standard treatment modality for colon cancer. However, performing intracorporeal anastomosis (IA) totally laparoscopic (TLRH) remains challenge some surgeons. To simplify IA in TLRH we used self-pulling and latter transection (SPLT) reconstruction TLRH, compared this procedure with overlap laparoscopy-assisted (LARH) order to evaluate its safety effectiveness. Methods Patients cancer who underwent SPLT-TLRH, or LARH between July 2019 June 2023...

10.3389/fonc.2024.1320508 article EN cc-by Frontiers in Oncology 2024-01-25

Sleep traits have been linked to diseases; particularly, their impact on cancer has received increasing attention. This study aimed investigate whether sleep a causal relationship with colorectal (CRC) using two-sample Mendelian randomization (TSMR).

10.21037/jgo-24-11 article EN Journal of Gastrointestinal Oncology 2024-08-01

Summary The production process of coalbed methane (CBM) includes and is controlled by desorption, diffusion, seepage processes acting conjointly. A coal reservoir commonly has a low permeability. Well stimulation applied to increase the CBM production, during which contact between fracturing fluid seam unavoidable. Developed microfractures, large specific surface area, high capillary pressure generate serious damage easily caused fluid, can affect CBM. Therefore, we presented multiscale...

10.2118/176297-pa article EN SPE Production & Operations 2016-11-04

Abstract The production process of coalbed methane (CBM) includes desorption, diffusion and seepage, the is controlled by these three processes together. permeability coal reservoir generally low. To increase production, well stimulation needs to be applied, in which contact between fracturing fluid seam inevitable. Developed micro-fractures, large specific surface area high capillary pressure generate serious damage easily caused fluid, can affect methane. Therefore, multi-scale mass...

10.2118/176297-ms article EN 2015-10-20

Abstract Roux‐en‐Y (RY) and Billroth II with Braun (BB) reconstruction are two similar methods of after distal gastrectomy (DG). Currently, it is unclear which method superior. This meta‐analysis was performed to compare the safety efficacy BB RY DG for gastric cancer. A literature search Pubmed, Embase, Web Science, Cochrane Library conducted identify studies comparing cancer until end October 2022. Main outcomes assessed were perioperative outcomes, postoperative complications, functional...

10.1002/mog2.48 article EN cc-by MedComm – Oncology 2023-08-09

Abstract Gas injection has become an important means of enhancing oil recovery (EOR) in clastic reservoirs, the Donghe Oilfield, Tarim, been undergoing gas to enhanced recovery. During injection, dynamic justification was most severe challenges, which needed monitor pressure profile, temperature profile and profile. Therefore, monitoring becoming part drive reservoirs. Oilfield characterized by ultra-deep (>6000m), high (>140°C) content carbon dioxide, conventional manometer...

10.2523/iptc-21177-ms article EN 2021-03-15

BACKGROUND Due to the prolonged life expectancy and increased risk of colorectal cancer (CRC) among patients with human immunodeficiency virus (HIV) infection, prognosis pathological features CRC in HIV-positive require examination. AIM To compare differences oncological features, surgical safety, between without HIV infection who have at same tumor stage site. METHODS In this retrospective study, we collected data from -negative underwent radical resection for CRC. Using random stratified...

10.4240/wjgs.v16.i1.29 article EN World Journal of Gastrointestinal Surgery 2024-01-25

Abstract Background Temporary ileostomy (TI) has proven effective in reducing the severity of anastomotic leakage after rectal cancer surgery; however, some ileostomies fail to reverse over time, leading conversion into a permanent stoma (PS). In this study, we aimed investigate preoperative risk factors and cumulative incidence TI non-closure sphincter-preserving surgery for cancer. Materials Methods We conducted meta-analysis searching Embase, Web Science, PubMed, MEDLINE databases from...

10.21203/rs.3.rs-3888064/v1 preprint EN cc-by Research Square (Research Square) 2024-01-26

Background. Protective ileostomy can effectively prevent severe anastomotic leakage after rectal cancer surgery; however, the optimal timing for closure during adjuvant chemotherapy remains unclear. This study aimed to explore safety and long-term outcomes of early chemotherapy. Method. Patients who underwent laparoscopic surgery combined with protective between April 2017 2021 were retrospectively evaluated. divided into an group (group A) a late B). Results. A total 215 patients included...

10.1155/2024/2410643 article EN cc-by Canadian Journal of Gastroenterology and Hepatology 2024-03-20

Background: The muscle cells myocytes are differentiated for the purpose of contraction function, which plays a major role in body metabolism and energy haemostasis, through different metabolic pathways, such as glucose protein pathways. Alanine aminotransferase (ALT) crucial by reversibly catalysing transamination between alanine a-ketoglutarate to form pyruvate glutamate mediating conversion these four intermediate metabolites. ALT important roles homeostasis during fasting prolonged...

10.7759/cureus.59331 article EN Cureus 2024-04-30

The ligamentum teres hepatis may block the field of vision during totally laparoscopic gastrectomy (TLG), especially in patients with obesity.

10.1089/lap.2024.0136 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2024-08-01

Abstract Background For patients with rectal cancer, the utilization of temporary ileostomy (TI) has proven effective in minimizing occurrence severe complications post-surgery, such as anastomotic leaks; however, some are unable to reverse time or even develop a permanent stoma (PS). We aimed determine preoperative predictors associated TS failure and validate appropriate predictive models improve patients’ quality life. Methods This research included 403 cancer who underwent ileostomies...

10.1186/s12885-024-12642-7 article EN cc-by BMC Cancer 2024-07-22

Abstract Casing failure probability is high in Tarim Oilfield, due to pressure temperature and sality operational environment, near 6% of total wells were damaged during their production life, which has serious impacts on the development well pattern, resulting unbalanced injection-production. Based analysis situation distribution casing damage located northwest China, was discovered 1989, Its formation unwanted characteristics (150°C) salinity (250000mg/L), order treatment wells, a new type...

10.2523/iptc-19553-ms article EN Day 2 Wed, March 23, 2022 2019-03-22

Abstract Background In some earlier studies, self-pulling and later transection (SPLT) esophagojejunostomy (E-J) was incorporated into total laparoscopic gastrectomy (TLTG) procedures. Its effectiveness safety, however, remain unknown. This study compared (SPLT)-E-J in TLTG with conventional E-J laparoscopic-assisted (LATG) order to assess the short-term safety efficacy of TLTG. Methods research analyzed patients gastric cancer who received SPLT-TLTG or LATG between January 2019 December...

10.1186/s12893-023-02077-5 article EN cc-by BMC Surgery 2023-06-29

Abstract Dabei and Dina 2 gas fields located in Tarim Oilfield are HTHP high production condensate fields. The formation temperature is 136°C, the pressure 105MPa, of single well 40×104m3/d~100×104m3/d, 35t/d~86t/d. After started production, oil continues to fluctuate decline due wellbore plugging. By 2019, more than 80% wells have plugging problem, some reduced over 50%, a few even shut in, normal seriously affected. In field, organic substances obtained wellhead nearby pipes during passing...

10.2523/iptc-21787-ms article EN 2021-03-15
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