A5071274261- MicroRNA in disease regulation
- Luminescence and Fluorescent Materials
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- RNA modifications and cancer
- Cytokine Signaling Pathways and Interactions
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
The First People's Hospital of Wenling
2020-2021
Wenzhou Medical University
2012-2013
First Affiliated Hospital of Wenzhou Medical University
2012
N-Doped carbon dots synthesized by a one-pot solvothermal route displayed tunable luminescence due to different N contents. They could be directly applied in the imaging of peritoneal macrophages mice. This study provides new method tune carbon-based materials through non-metal doping.
Suppressors of cytokine signaling, SOCS1 and SOCS3, are important negative regulators Janus kinase 2/signal transducers activators transcription which is constitutively activated in myeloproliferative neoplasms (MPNs) leukemia. Curcumin has been shown to possess anticancer activity through different mechanisms. However, whether curcumin can regulate the expression SOCS3 still unknown. Here, we found that elevated via triggering acetylation histone regions promoter K562 HEL cells. As a novel...
Objective: To assess miR-155’s effect on aplastic anemia (AA) rats. Methods: In the present study, healthy rats (control group) and AA including with miR-155 overexpression (experimental group I) those deficiency II), were selected. The levels of miR-155, STAT3 (a key gene in signaling pathway) phosphorylated (p-STAT3) control experimental detected via qPCR Western blotting. Moreover, number white blood cells (WBCs), red (RBCs), platelets (PLTs) hemoglobin (HGB) level also measured. Results:...
Non-small-cell lung cancer (NSCLC) is one of the most frequent solid tumors and regarded as a significant threat to individual health around world. MicroRNAs (miRs) are recognized critical governors gene expression during carcinogenesis, while their clinical significance mechanism in NSCLC occurrence development required for further investigation. In this report, we characterized functional role miR-598 its regulation NSCLC. The level tissues cell lines was detected by qRT-PCR. A549 cells...