A5101750213- Pelvic floor disorders treatments
- Cardiac Ischemia and Reperfusion
- Cardiac Fibrosis and Remodeling
- Optical properties and cooling technologies in crystalline materials
- Glutathione Transferases and Polymorphisms
- CAR-T cell therapy research
- Cardiac electrophysiology and arrhythmias
- Signaling Pathways in Disease
- Urinary Bladder and Prostate Research
- Cancer therapeutics and mechanisms
- Hepatocellular Carcinoma Treatment and Prognosis
- Immune Cell Function and Interaction
- Peptidase Inhibition and Analysis
- Endometrial and Cervical Cancer Treatments
- Immune cells in cancer
- Cancer Immunotherapy and Biomarkers
Xiamen University
2021
Guangdong Academy of Medical Sciences
2019-2020
Guangdong Provincial People's Hospital
2019-2020
South China University of Technology
2020
Southern Medical University
2009-2010
Genetically T cells modified with cancer-specific chimeric antigen receptors (CARs) showed great promise in mediate tumor regression, especially patients advanced leukemia. However, the therapeutic effect against solid tumors is not as prominent anticipated to exhibit potent antitumor efficacy. The underlying mechanism maybe attributed inhibitory co-stimulatory pathways such (PD1/PDL1), which provide an escape from immunosurveillance. Therefore, by exchanging transmembrane and cytoplasmic...