A5005091420- Plant Molecular Biology Research
- Soybean genetics and cultivation
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Lipid metabolism and biosynthesis
- Magnetic confinement fusion research
- Plant biochemistry and biosynthesis
- Postharvest Quality and Shelf Life Management
- Plant Physiology and Cultivation Studies
- Cardiac Arrest and Resuscitation
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Superconducting Materials and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Sepsis Diagnosis and Treatment
- Plant Gene Expression Analysis
- Plant pathogens and resistance mechanisms
- Trauma and Emergency Care Studies
- Legume Nitrogen Fixing Symbiosis
- Pulsars and Gravitational Waves Research
- Plant Surface Properties and Treatments
Chinese Academy of Sciences
2015-2023
State Key Laboratory of Plant Genomics
2015-2023
Institute of Genetics and Developmental Biology
2015-2023
Hebei Medical University
2012-2020
Third Hospital of Hebei Medical University
2012-2020
Technical Institute of Physics and Chemistry
2020
University of Chinese Academy of Sciences
2017-2019
Soybean (Glycine max) production is severely affected in unfavorable environments. Identification of the regulatory factors conferring stress tolerance would facilitate soybean breeding. In this study, through coexpression network analysis salt-tolerant wild soybeans, together with molecular and genetic approaches, we revealed a previously unidentified function class B heat shock factor, HSFB2b, salt response. We showed that HSFB2b improves promotion flavonoid accumulation by activating one...
WRKY transcription factors play important roles in response to various abiotic stresses. Previous study have proved that soybean GmWRKY54 can improve stress tolerance transgenic Arabidopsis. Here, we generated plants and further investigated biological mechanisms of drought stress. We demonstrated expression GmWRKY54, driven by either a constitutive promoter (pCm) or drought-induced (RD29a), confers tolerance. is transcriptional activator affects large number stress-related genes as revealed...
Soybean is an important crop worldwide, but its production severely affected by salt stress. Understanding the regulatory mechanism of response crucial for improving tolerance soybean. Here, we reveal a role nuclear factor Y subunit GmNFYA in soybean likely through regulation histone acetylation. induced Overexpression significantly enhances stable transgenic plants inducing salt-responsive genes. Analysis with hairy roots also supports conclusion. interacts GmFVE, which functions putative...
Soybean (Glycine max) is one of the most important oilseed crops. However, regulatory mechanism that governs process oil accumulation in soybean remains poorly understood. In this study, GmZF392, a tandem CCCH zinc finger (TZF) protein which was identified our previous RNA-seq analysis seed-preferred transcription factors, found to function as positive regulator lipid production. GmZF392 promotes seed both transgenic Arabidopsis and stable plants by binding bipartite cis-element, containing...
Abiotic stress is one of the most important factors reducing soybean yield. It essential to identify regulatory contributing responses. A previous study found that tandem CCCH zinc-finger protein GmZF351 an oil level regulator. In this study, we discovered gene induced by and overexpression confers tolerance transgenic soybean. directly regulates expression GmCIPK9 GmSnRK, leading stomata closing, binding their promoter regions, which carry two CT(G/C)(T/A)AA elements. Stress induction...
Objective: To determine the role of microRNA 21(miR-21) on left ventricular remodeling rat heart with ischemia-reperfusion (I/R) injury and to investigate underlying mechanism miR-21 mediated myocardium protection.Methods: Rats were randomly divided into three groups: an I/R model group Ad-GFP (Ad-GFP group), Ad-miR-21 (Ad-miR-21 group) a sham-surgery group.Changes in hemodynamic parameters recorded at 1 week after I/R.Histological diagnosis was achieved by hematoxylin eosin (H&E).Left (LV)...
Abstract Ethylene perceived by a family of five receptors regulates many developmental processes in Arabidopsis . Here we conducted the yeast two-hybrid assay to screen for additional unidentified proteins that interact with subfamily II ethylene receptor ETR2. Three SAUR proteins, named SAUR76, 77 and 78, were identified associate both ETR2 EIN4 different assays. Interaction SAUR76 SAUR78 was further verified co-immunoprecipitation bimolecular fluorescence complementation (BiFC) Expressions...
Seed oil is a momentous agronomical trait of soybean (Glycine max) targeted by domestication in breeding. Although multiple oil-related genes have been uncovered, knowledge the regulatory mechanism seed biosynthesis currently limited. We demonstrate that seed-preferred gene GmZF351, encoding tandem CCCH zinc finger protein, selected during domestication. Further analysis shows GmZF351 facilitates accumulation directly activating WRINKLED1, BIOTIN CARBOXYL CARRIER PROTEIN2, 3-KETOACYL-ACYL...
Reactive oxygen species (ROS)-induced cardiac myocyte injury resulting from changes in the expression levels of multiple genes plays a critical role pathogenesis numerous heart diseases. The purpose this study was to determine potential roles microRNA-214 (miR-214) hydrogen peroxide (H2O2)-mediated gene regulation myocytes. In study, we used quantitative real-time RT-PCR (qRT-PCR) demonstrate that miR-214 upregulated myocytes after treatment with H2O2. We transfected cells pre-miR-214...
Background: Sepsis is a life-threatening organ dysfunction, initiated by dysregulated host response to infection. This study aimed determine key genes and microRNAs (miRNAs) correlated with sepsis. Methods: Three patients sepsis three healthy individuals treated as controls were recruited in the current study. To identify differentially expressed mRNAs (DEmRNAs) miRNAs (DEmiRNAs) between controls, RNA-sequencing bioinformatics analysis conducted. DEmiRNA-target DEmRNAs functional annotation...
This study set out to determine key lncRNAs correlated with sepsis via constructing competing endogenous RNA (ceRNA) network.Three septic patients and three healthy controls were recruited obtain lncRNA profiles in this current study. Combined the mRNA by RNA-sequencing, an integrated analysis of expression downloaded from GEO was performed differentially expressed mRNAs (DEmRNAs). Based on (DElncRNAs) DEmRNAs acquired present miRNAs (DEmiRNAs) previous study, a ceRNA network constructed....