A5024333340- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Cancer Treatment and Pharmacology
- Digital Mental Health Interventions
- Mobile Health and mHealth Applications
- Circadian rhythm and melatonin
- Chemical Reactions and Isotopes
- Neutropenia and Cancer Infections
Betsi Cadwaladr University Health Board
2018
Hôpital Paul-Brousse
2012-2016
Assistance Publique – Hôpitaux de Paris
2016
To assess the impact of chronomodulated irinotecan fluorouracil-leucovorin and oxaliplatin (chronoIFLO4) delivered at home on daily life patients with cancer in real time using a home-based e-Health multifunction multiuser platform. This involved multidimensional telemonitoring circadian rest-activity rhythm (CircAct), sleep, patient-reported outcome measures, body weight changes (BWCs).Patients received chronoIFLO4 fortnightly home. Patients completed 19-item MD Anderson Symptom Inventory...
Telehealth solutions can improve the safety of ambulatory chemotherapy, contributing to maintenance patients at their home, hence improving well-being, all while reducing health care costs. There is, however, need for a practicable multilevel monitoring solution, encompassing relevant outputs involved in pathophysiology chemotherapy-induced toxicity. Domomedicine embraces delivery complex and medical procedures patient's home based on modern technologies, thus it offers an integrated...
TPS9154 Background: Self-rated symptoms contribute to the Quality of Life (QoL) cancer patients (pts) and impact on prognosis. Behavioural functions are controlled by circadian timing system (CTS), through a network molecular clocks that time cellular proliferation drug metabolism (Lévi et al. ARPT 2010). Chronotherapy aims at reduction treatment-related adjustment chemotherapy delivery CTS. Cancer chronotherapy is delivered home using programmable pumps, avoids familial social disruption....
e20519 Background: The rest-activity rhythm is a biomarker of the circadian timing system, whose disruption both accelerates cancer progression in experimental models (Filipski et al. JNCI 2002, 2005) and predicts for poor overall survival patients (pts) (Innominato Cancer Res 2009; Int J 2012). Here we investigate relevance early signals antitumor efficacy intravenous Cet chronomodulated triplet HAI pts with unresectable refractory LM-CRC. Methods: Rest-activity was monitored q1min using...