Hongbing Jiang

ORCID: 0000-0002-2624-2281
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About
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Research Areas
  • Cleft Lip and Palate Research
  • Craniofacial Disorders and Treatments
  • RNA modifications and cancer
  • Folate and B Vitamins Research
  • Cancer-related molecular mechanisms research
  • RNA Research and Splicing
  • Periodontal Regeneration and Treatments
  • Dental Radiography and Imaging
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Dental Implant Techniques and Outcomes
  • Metal and Thin Film Mechanics
  • Cancer-related gene regulation
  • Gene expression and cancer classification
  • Wnt/β-catenin signaling in development and cancer
  • Diabetes and associated disorders
  • Skin and Cellular Biology Research
  • Phagocytosis and Immune Regulation
  • Intermetallics and Advanced Alloy Properties
  • Congenital Ear and Nasal Anomalies
  • Molecular Biology Techniques and Applications
  • High-Velocity Impact and Material Behavior
  • RNA and protein synthesis mechanisms
  • Impact of Light on Environment and Health
  • Advanced Sensor and Control Systems

Nanjing Medical University
1999-2024

Nanjing Health and Health Commission
2019

Kunming University of Science and Technology
2019

National Administration of Surveying, Mapping and Geoinformation of China
2017

Despite therapeutic advancements, there has been little improvement in the survival status of patients with oral squamous cell carcinoma (OSCC). HOX antisense intergenic RNA (HOTAIR) shown to be dysregulated several cancer types. However, roles HOTAIR OSCC remain largely unknown. In this study, we investigated association expression clinicopathological features and crucial modulation tumor progression. Our results showed that was highly expressed both tissue samples lines compared...

10.1002/mc.23159 article EN Molecular Carcinogenesis 2020-01-28

Super-enhancers (SEs) have been recognized as key epigenetic regulators underlying cancer stemness and malignant traits by aberrant transcriptional control promising therapeutic targets against human cancers. However, the SE landscape their roles during head neck squamous cell carcinoma (HNSCC) development especially in stem cells (CSCs) maintenance remain underexplored yet. Here, we identify leukemia inhibitory factor (LIF)-SE a representative oncogenic to activate LIF transcription HNSCC....

10.1002/advs.202404476 article EN cc-by Advanced Science 2024-08-29

Mapping urban areas at the regional and global scales has been used in ecology, environment, sociology, other subjects. Recently, it become increasingly popular to extract from night-time light remote-sensing data. In this article, we reported an alternative method information of VIIRS Day/Night Band (DNB) MODIS normalized differential vegetation index (NDVI) data based on adaptive mutation particle swarm optimization (AMPSO) algorithm Support Vector Machine (SVM) classification algorithm....

10.1080/01431161.2017.1339927 article EN International Journal of Remote Sensing 2017-06-13

Abstract Marginal bone loss (MBL) is one of the leading causes dental implant failure. This study aimed to investigate feasibility machine learning (ML) algorithms based on trabeculae microstructure parameters predict occurrence severe MBL. Eighty-one patients (41 MBL cases and 40 normal controls) were involved in current study. Four ML models, including support vector (SVM), artificial neural network (ANN), logistic regression (LR), random forest (RF), employed The area under receiver...

10.1038/s41598-020-75563-y article EN cc-by Scientific Reports 2020-10-28

Let-7 and Lin28 establish a double-negative feedback loop to affect several biological processes, such as differentiation of stem cell, invasion metastasis tumorigenesis. In this study, we systematically investigated the associations between 6 potentially functional SNPs let7 genes risk oral cavity cancer with case-control study including 384 cases 731 controls. We found that variant allele (T) rs221636 Lin28B was significantly associated reduced [odds ratio (OR) = 0.73, 95% confidence...

10.1038/srep07434 article EN cc-by-nc-nd Scientific Reports 2014-12-11

Diabetes exacerbates the prevalence and severity of periodontitis, leading to severely periodontal destruction ultimately tooth loss. Delayed resolution inflammation is a major contributor diabetic periodontitis (DP) pathogenesis, but underlying mechanisms this imbalanced immune homeostasis remain unclear. Here, we discovered that insufficient SIRT6 as histone deacetylase in macrophages led unresolved aggravated both human mouse DP with accumulated apoptotic neutrophil (AN) higher generation...

10.2139/ssrn.4201648 article EN SSRN Electronic Journal 2022-01-01

Nonsyndromic orofacial clefts (NSOCs) are among the most common birth defects and occur in 1 per 700 to 1000 live births worldwide, although incidence varies with geographic origin, ethnicity, socioeconomic status. can be divided into lip only (CLO), both palate (CLP), (CPO). carry large public health burdens because of immediate long-term medical costs, increased overall mortality, social impacts on patients their families. Any disturbance from genetic background or environmental...

10.1097/01.ogx.0000426486.51806.a3 article EN Obstetrical & Gynecological Survey 2013-01-01

Nonsyndromic orofacial clefts (NSOCs) are among the most common birth defects and occur in 1 per 700 to 1000 live births worldwide, although incidence varies with geographic origin, ethnicity, socioeconomic status. Non-syndromic can be divided into lip only (CLO), both palate (CLP), (CPO). carry large public health burdens because of immediate long-term medical costs, increased overall mortality, social impacts on patients their families. Any disturbance from genetic background or...

10.1097/01.ogx.0000427630.95758.c1 article EN Obstetrical & Gynecological Survey 2013-02-01

Abstract In this paper, multi-pass hot compression experiments of pure titanium TA1 was investigated with Gleeble-3500 thermal simulation test machine at an initial temperature 880°C. The purpose is to investigate the effects on deformation a electron beam cold hearth melting (EBCHM) single casting slab. microstructure sample analyized by metallograph and backscatter diffraction (EBSD), dynamic recovery found be main mechanism. recrystallization nucleation mechanism were mainly bulging grain...

10.1088/1755-1315/332/3/032032 article EN IOP Conference Series Earth and Environmental Science 2019-10-01

Abstract Marginal bone loss (MBL) is one of the leading causes dental implant failure. This study aimed to investigate feasibility machine learning (ML) algorithms based on trabeculae microstructure parameters predict occurrence severe MBL. Eighty-one patients (41 MBL cases and 40 normal controls) were involved in current study. Four ML models, including support vector (SVM), artificial neural network (ANN), logistic regression (LR), random forest (RF), employed The area under receiver...

10.1101/2020.09.16.20195602 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-09-18
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