- Antimicrobial Peptides and Activities
- Eicosanoids and Hypertension Pharmacology
- Advanced Glycation End Products research
- Protein Hydrolysis and Bioactive Peptides
- Nuclear Structure and Function
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoparticles: synthesis and applications
- Nanocomposite Films for Food Packaging
- Polydiacetylene-based materials and applications
- Sperm and Testicular Function
- Synthesis and biological activity
- Insect Utilization and Effects
- Reproductive Biology and Fertility
- Multicomponent Synthesis of Heterocycles
- Medicinal Plants and Neuroprotection
- Antiplatelet Therapy and Cardiovascular Diseases
- Peroxisome Proliferator-Activated Receptors
Osmania University
2017-2021
Centre for Cellular and Molecular Biology
2013
Central University of Kerala
2012
University of Kerala
2011
Divergent angiogenic responses occur in different organs a diabetic state. Many of the pathological effects were mediated by advanced glycation end products (AGEs) non-enzymatically glycated molecules. Investigations carried out using model systems to examine whether response AGEs is influenced cellular microenvironment. AGE-albumin increased angiogenesis chick chorioallantoic membrane (CAM). It also sprouting rat aortic rings and expression markers CD31 E-selectin growth factor, vascular...
The biogenic synthesis of silver nanoparticles was achieved by using gum kondagogu (Cochlospermum gossypium), a natural biopolymer (Gk-AgNPs). Synthesised were characterised UV–visible spectroscopy, inductively coupled plasma-atomic emission spectrometer, X-ray diffraction, transmission electron microscope techniques. nano particle size determined found to be 3.6 ± 2.2 nm. synthesised Gk-AgNPs showed antifungal activity and exhibited minimum inhibitory concentration minimal fungicidal values...
Abstract Background Acrosomal proteins play crucial roles in the physiology of fertilization. Identification localizing to acrosome is fundamental understanding its contribution Novel are still being reported from acrosome. In order capture yet unreported particular and sperm general, 2D-PAGE mass spectrometry analysis mouse was done. Results One protein spots identified above study NCBI database as a hypothetical Riken cDNA 1700026L06 that localizes chromosome number 2. Immunofluorescence...
In an attempt to synthesize new chemical entities with promising biological activity, a set of six novel pyrimidinedione analogues 6(a-f) was prepared. The compound 4 coupled different amines by using HBTU as coupling reagent. derivatives were characterized 1HNMR,13CNMR and HRMS. evaluated for their antibacterial antioxidant activity. DPPH ABTS methods used test the activity moieties. Among analogues, 6b, 6d, 6f exhibited significant effects. paper disc diffusion method adopted evaluate...