A5068084185- Immune Response and Inflammation
- Vitamin C and Antioxidants Research
- Reproductive Biology and Fertility
- Viral-associated cancers and disorders
- Sperm and Testicular Function
- Lymphoma Diagnosis and Treatment
- Preterm Birth and Chorioamnionitis
- Diet, Metabolism, and Disease
- Epigenetics and DNA Methylation
- Reproductive biology and impacts on aquatic species
- Histone Deacetylase Inhibitors Research
- Parvovirus B19 Infection Studies
- Vitamin D Research Studies
- Cell Adhesion Molecules Research
- Essential Oils and Antimicrobial Activity
- Cancer-related gene regulation
- Parasitic infections in humans and animals
- Insects and Parasite Interactions
- Selenium in Biological Systems
- Parasitic Infections and Diagnostics
- Sesame and Sesamin Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Chemotherapy-induced organ toxicity mitigation
- Hair Growth and Disorders
- Biomarkers in Disease Mechanisms
Fasa University of Medical Sciences
2014-2024
Curcumin is the well-known compound which extracted from turmeric powder, dried rhizome of Curcuma longa Linn. This have been used for treatment various disorders including inflammation. In this study we analyzed effect curcumin on arthritis induced by adjuvant in rats, considering changes methionine sulfoxide reductase A (MSRA) expression and antioxidant enzymes levels.Five groups adult male Wistar rats (n=10), were randomly selected as control, placebo, experimental 1, 2 3. The induction...
Calcium channels play essential roles in sperm motility. A family of sperm-specific cation including CatSper1–4 has been identified as voltage-dependent ion that act motility regulators. Methamphetamine is known to cause apoptosis seminiferous tubules and affect quality. This research was conducted investigate the effects methamphetamine on expression CatSper Mvh genes. Thirty-six adult Wistar rats were divided into four groups nine each: control experimental 1, 2, 3. The group received no...
Alamandine is a new member of the angiotensin family. Here, we studied mRNA and protein expression cardiac angiotensin-converting enzyme 2 (ACE2) in chronic phase rat model 2-kidney, 1-clip hypertension (2K1C), effects 2-week alamandine infusion on blood pressure, indices, ACE2 hearts. The rats were subjected to sham-operation or placement plexiglass clips around left renal artery. Alamandine, at dose 600 µg/kg/d, was administered for weeks via an osmotic mini-pump. At 18 weeks, after...
Hepatitis B virus (HBV) as an infectious disease that has nine genotypes (A - I) and a 'putative' genotype J.The aim of this study was to identify the rare codon clusters (RCC) in HBV genome evaluate these RCCs proteins structure.For detection protein family accession numbers (Pfam) proteins, UniProt database Pfam search tool were used. Protein is comprehensive accurate collection domains families. It contains annotation each form textual descriptions, links other resources literature...
Maintaining sperm motility after ejaculation is important for fertilisation. Apoptosis may play an role to reduce ejaculation. The aim of this study was perceive whether or not increase in apoptosis reduces a higher degree and it can be predicted by laboratory tests, such as chromatin structure assay (SCSA). Fifty-one Asthenozoospermia 20 fertile subjects participated study. SCSA applied using flow cytometry. Fluorescein-labelled inhibitors Caspases (FLICA) method used assessment active...
This study is an attempt to determine the power of SCSA and TUNEL for evaluation apoptosis status apoptosis-related motility depletion in Asthenozoospermia. Fifty-one semen samples from Asthenozoospermic 20 fertile men participated this study. were applied assessment DNA integrity by flow cytometry. Annexin V conjugated with FITC labelling FLICA method used externalisation phosphatidylserine spermatozoon active Caspase 3 respectively. results shown have a significant correlation EPS live (r...
Purpose. The role of oxidative stress in Aluminum (Al)-induced apoptotic effects has been investigated and suicidal death erythrocytes, eryptosis, is characterized by cell shrinkage phosphatidylserine externalization (PSE) at the surface erythrocyte membrane. Eryptosis stimulated an increase cytosolic Ca2+ concentration reactive oxygen species (ROS). This ex vivo study was conducted to evaluate effect well-known antioxidants including vitamin C (vit C) N-acetylcysteine (NAC), against...
COVID-19 is one of the worst pandemics worldwide, and its diagnosis treatment are great importance. Recent evidence has shown that circular RNA (circRNA deregulation involved in different infectious diseases. In present study, we tried to investigate expression cirRNAs RasGEF1B (hsa_circ_0127052), HIPK3 (hsa_circ_100783), GATAD2A (hsa_circ_0050236) patients.
Gastric cancer (GC) is very common in Iran. Daily consumption of pickled vegetables a routine dietary habit most areas Because have been associated with GC it can be importance to study the relationship between two. We therefore studied histo-morphological effects on Rabbit gastric mucosa. Forty and twenty healthy male rabbits were respectively allocated experimental control groups. The fed freely (experimental group) fresh (control for 1 yr. mucosa was examined results compared. In addition...
Background: P-glycoprotein (P-gp) is a transmembrane pump encoded by MDR1 gene. It contributes in protection of the cells against xenobiotic and toxic compounds. P-gp also multidrug resistance acute lymphoblastic leukemia (ALL). Human polymorphism include C to T exchange at position 3435, individuals with TT have lower expression than others CC genotypes. Accumulation xenobiotics can cause some diseases like cancers.Materials Methods: To evaluate MDR1C3435T gene adult patients ALL, 54 96...
Preterm delivery is one of the main causes infant death. Therefore, prediction preterm may eliminate a large number prenatal complications.The present study aimed to understand if can be predicted by assessing maternal plasma fibronectin concentration.Serum samples from 105 pregnant women participating in this were collected. The measured at 24-28 wk gestation and again 32-36 gestation. Unfortunately, only 65 women, returned for second sampling. was analyzed using ELISA method its...