A5029448622- Synthesis of β-Lactam Compounds
- Synthesis and Catalytic Reactions
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Synthesis and Biological Evaluation
- Insect Pest Control Strategies
- Crystallography and molecular interactions
- Asymmetric Synthesis and Catalysis
- Essential Oils and Antimicrobial Activity
- Chemical Synthesis and Reactions
- Synthesis and Characterization of Pyrroles
- Chemical Synthesis and Analysis
- Conducting polymers and applications
- Inflammatory mediators and NSAID effects
- Antibiotics Pharmacokinetics and Efficacy
- Traditional and Medicinal Uses of Annonaceae
- Perovskite Materials and Applications
- Mosquito-borne diseases and control
- Moringa oleifera research and applications
- Chemical synthesis and alkaloids
- Carbohydrate Chemistry and Synthesis
- Porphyrin and Phthalocyanine Chemistry
- Quinazolinone synthesis and applications
- Ginger and Zingiberaceae research
- Multicomponent Synthesis of Heterocycles
Islamic Azad University, Estahban Branch
2019-2025
Shiraz University
2011-2025
Shiraz University of Technology
2019
Instituto de Síntesis Química y Catálisis Homogénea
2015-2017
Universidad de Zaragoza
2013-2017
Strategic move: Isatin as a core structure has inspired the development of useful catalytic strategies to give access interesting molecular architectures with biological activity.
Many people around the world suffer from malaria, especially in tropical or subtropical regions. While malaria medications have shown success treating there is still a problem with resistance to these drugs. Herein, we designed and synthesized some structurally novel benzotriazole-β-lactams using 2-(1H-benzo[d][1,2,3]triazol-1-yl)acetic acid as key intermediate. To synthesize target molecules, ketene-imine cycloaddition reaction was employed. First, The of 1H-benzo[d][1,2,3]triazole...
Abstract While aging inevitably changes our skin, this complex biological process involves much more than just getting older. As the body's largest organ, skin constantly safeguards us from harmful environmental pathogens and plays a key role in overall well‐being. This study investigated development evaluation of nanogel containing Rosa damascena essential oil for its potential anti‐aging properties. The was prepared primary nanoemulsion with particle size 86 ± 4 nm. Antioxidant activity,...
Herein, we report our preliminary results concerning the first promising asymmetric synthesis of highly functionalized 2-oxospiro-[indole-3,4′-(1′,4′-dihydropyridine)] via reaction an enamine with isatylidene malononitrile derivatives in presence a chiral base organocatalyst. The moderate, but promising, enantioselectivity observed (30%–58% ee (enantiomeric excess)) opens door to new area research for construction these appealing spirooxindole skeletons, whose enantioselective syntheses are...
The first cinchona-alkaloid-organocatalyzed enantioselective synthesis of chiral 1,4-dihydropyridine derivatives is described. Bis-cinchona catalyst 3b activates the Michael addition reaction between malononitrile 2 and enamines 1, affording appealing highly substituted 1,4-dihydropyridines 4 with very good results in most cases. This one few examples by an catalytic procedure. final compounds are interest for their potential biological activity. efficient protocol opens door to a new area...
The use of larvicides, especially in endemic regions, is recommended for malaria control. However, due to the excessive synthetic resistance mosquitoes and environmental pollution have been challenges. In current study, nanoliposome containing clove cinnamon essential oils their major ingredients, i.e., eugenol cinnamaldehyde, were first prepared; particle size successful loading investigated using DLS (Dynamic Light Scattering) ATR-FTIR (Attenuated Total Reflection-Fourier Transform...
Abstract Several monocyclic β ‐lactams have been synthesized via a [2+2] ketene–imine cycloaddition reaction (Staudinger reaction) and evaluated for their biological activities. The structure of products was confirmed by spectral data elemental analyses. ‐Lactams 4 b h exhibited 31 27 anti‐inflammatory ratios, respectively, which are as well the well‐known dexamethasone corticosteroid with 32 ratio. two most active compounds showed IC 50 values more than 200 μM against HepG2 cell line, in...
Use of polymers as promising strategies to increase the reliability and boosting PV performances perovskite solar cells.
Abstract β ‐Lactam antibiotics are critical antibacterial agents and have rapidly become active ingredients in modern medicine. On the other hand, face of increasing rate resistance, there many concerns requiring design synthesis new agents. Herein, we synthesized some monocyclic ‐lactams with various substituents through Staudinger cycloaddition reaction. The formation cycloadducts was confirmed by elemental analysis different spectral data, including NMR, FTIR, Mass spectroscopy....
In the title compound, C(22)H(16)Cl(2)N(2)O(5), nearly planar four-membered β-lactam ring [maximum deviations of 0.011 (2) for N atom] makes dihedral angles 68.34 (13), 83.04 (13) and 3.37 (13)° with dichloro-, nitro- meth-oxy-phenyl rings, respectively. The crystal structure is stabilized by C-H⋯O hydrogen-bond inter-actions. addition, a π-π stacking inter-action [centroid-centroid distance = 3.6622 (12) Å] observed between nitro-phenyl rings.