Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The majority of infected people, including healthcare workers are unaware their status. This study aimed to determining seroprevalence hepatitis associated factors among northern Tanzania.This cross-sectional included 442 (HCWs) from tertiary teaching hospital Tanzania before nationwide vaccination campaign 2004. Questionnaire- based interviews were used obtain detailed...

Introduction . Although ART has improved the outcome of people living with HIV/AIDS, still some patients develop TB while receiving ART. The literature on magnitude this problem is scarce in our setting especially northwestern Tanzania. This study was designed to determine prevalence active among HIV and assess its potential risk factors. Methods A retrospective cohort done adult HIV-positive initiated at Bugando Medical Centre. Patients who were positive before initiation excluded. Data...

Highly Active Antiretroviral therapy (HAART) reverses the effect of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) by durably suppressing viral replication. This allows CD4 gain to levels that are adequate enough restore body's capability fight against opportunistic infections (OIs). Patients with poor immune recovery have been shown higher risk developing both AIDS and non related clinical events. study aimed at assessing proportions factors in adult...

Introduction . HIV still causes high mortality despite use of ART. This study was designed to determine the prevalence and risk factors among patients receiving ART in northwestern rural Tanzania. Methods A retrospective on done at Sengerema Mwanza, The data demography, date diagnosis, WHO stage, opportunistic infections, CD4, hemoglobin, regimen, time outcome treatment as dead or alive were collected analyzed using STATA version 11. Results In total, 740 studied. median age 35 (27–42) years...

Client satisfaction has been found to be an important factor for the uptake and continuation of family planning services. This study aimed examine current status factors associated with client's services in Tanzania, which a high unmet need planning. The used data from Tanzania Service Provision Assessment survey 2014–2015. A facility was classified as having service readiness FP if it scored at least 67.7% on composite score based three domains (staff training guidelines, basic diagnostic...

BackgroundHIV/AIDS causes high morbidity and mortality through both immunosuppression complications not directly related to immunosuppression.Haematological abnormalities, including various cytopenias, occur commonly in HIV immune non-immune pathways.Though these could potentially cause serious clinical implications, published literature on the magnitude of this problem its associated factors Tanzania is scarce.This study aimed at determining prevalence risk HIV-associated cytopenias among...

With a growing access to free ART, switching of ART second line regimen has also become common following failure first regimens. Patients failing on regimens have been shown stand high risk subsequent The magnitude those who are virologicaly is not documented in our setting. This study was designed assess the and correlates treatment failure. A retrospective analysis patients for at least 1 year done Bugando care center. Information demographic, clinical laboratory data were collected...

Background Sub-therapeutic and supra-therapeutic plasma concentrations of antriretrovirals are the significant causes treatment failure toxicity respectively among HIV-infected patients. We conducted this study to determine pattern efavirenz nevirapine drug adult patients with immunological attending at a tertiary hospital in North-western Tanzania. Materials Methods A cross-sectional was who have been on either or based antiretroviral regimen for more than 6 months. Patients were serially...

Background. Liver fibrosis which is a common complication of chronic hepatitis B infection rarely diagnosed in low-resource countries due to limited capacity perform biopsy studies. Data on the utilization noninvasive techniques are feasible for diagnosis liver these settings among HIV-infected patients scarce. The objective this study was establish magnitude by using both aspartate-aminotransferase-to-platelets ratio and fibrosis-4 scores with associated coinfection antiretroviral therapy...

Background: Hypertension is common among diabetic patients. The co-existence of two conditions carries an excessive risk severe complications and mortalities. Limited information exists on the determinants poor hypertension control these We aimed at determining prevalence factors associated with in patients.Methods: Data patients who were also hypertensive attending outpatient clinic from 1 August 2015 to 31 December Bugando Medical Centre retrospectively analyzed. Uncontrolled was defined...

Optimal HIV treatment monitoring remains a big challenge in resource limited settings. Guidelines recommend the use of clinical and immunological criteria settings due to unavailability viral load monitoring; however their utility is questionable. This study aimed at assessing accuracy detecting failure among infected Tanzanian adults receiving first line ART.A clinic based cross sectional was conducted between February July 2011 Bugando Medical centre (BMC) care (CTC) involving patients...

Abstract Background Sustainability of research culture in Sub-Saharan Africa is threatened part by the lack a critical mass young researchers with requisite skills and interest to undertake careers. This paper describes an intensive mentorship programme combining hierarchical (vertical) peer-to-peer (horizontal) mentoring strategies among resource limited setting Africa. Methods A consortium three partnering large Tanzanian health training institutions (MUHAS, CUHAS KCMUCo) two collaborating...

Moderate to severe anemia is an important clinical problem in HIV patients on Highly Active Antiretroviral Therapy. The rate of progression and mortality this sub group high compared non anemic patients. In Saharan Africa with scale up Anti retroviral therapy, the magnitude not known especially Tanzania. This study aimed at determining correlates moderate receiving first line ART northwestern Tanzania.This was a cross sectional clinic based study, involving adult Therapy Bugando Medical...

Prostatic carcinoma carries a high morbidity and mortality if it is not diagnosed early. In resource limited countries, patients are at increased risk of being late as they operated for presumed benign prostatic hyperplasia. The information on the magnitude factors this problem in our setting could assist overall optimization care risk.A retrospective study who underwent prostatectomy enlargement was done Bugando University Hspital Tanzania. Patients' age, creatinine levels, urological...

Introduction. Smear positive TB carries high morbidity and mortality. The treatment aims at sputum conversion by two months of antituberculous. Patients who delay remain potentially infectious, with risk failure, drug resistance, Little is known about the magnitude this problem in our setting. This study was designed to determine prevalence factors delayed northwestern rural part Tanzania. Methods. a retrospective cohort involving smear patients Sengerema DDH 2015. Demographic data, HIV...

Bleeding esophageal varices is a deadly complication of liver cirrhosis. Guidelines recommend an early diagnosis before incident bleeding by screening all patients diagnosed with Though it has been reported elsewhere that the presence varies widely among cirrhotic this not assessed in Tanzania since endoscopy readily available for routine use our setting. This study was designed to determine prevalence and assess utility clinical parameters predicting northwestern Tanzania.A cross-sectional...

Background: Introduction and expansion of antiretroviral therapy (ART) have turned the tide HIV pandemic, thus helping people living with (PLHIV) achieve viral suppression. This success may need to be complemented by intensified adherence counseling (IAC) improve treatment. However, some PLHIV still face higher than acceptable loads despite being on Purpose: We investigated factors associated failure suppress load after three months IAC sessions. Patients Methods: cross-sectional study...

Background: Tuberculosis (TB) is still an important cause of morbidity and mortality worldwide. Though it can effectively be treated, a significant proportion patients die on the course their treatment. The objective this study was to determine outcome risk factors among diagnosed with TB in tertiary hospital north-western Tanzania.Methods: A retrospective cross sectional done all between January December 2015 at Bugando Medical Centre. Information demographic characteristics, smear...

Abstract Background Methadone therapy clinics have been recently introduced in Tanzania, aiming at reducing risk behaviors and infection rates of viral hepatitis HIV among people who use drugs. The objective this study was to estimate the prevalence, associated factors knowledge level these conditions drugs attending a methadone clinic Tanzania. Methods We enrolled 253 People using receiving therapy. Clinical data retrospectively collected from medical records face-to face interviews were...

Background: The prevalence and mortalities due to renal diseases is estimated be high in sub-Saharan Africa. Little known about these conditions among the hospitalized adult-patients Tanzania. objective of this study was determine magnitude, associated factors outcomes dysfunction inpatients at Bugando Medical Centre Mwanza, Tanzania.Methods: This both analytical cross section (for determining predictors) prospective cohort outcomes) study. Demographic, clinical laboratory data were...

there is an increased vulnerability for the development of common mental disorders during peripartum period as evidenced in depressive disorder.a cross sectional study was used to determine prevalence and risk factors associated with depression among pregnant women attending antenatal clinic (ANC) at Bugando Medical Centre (BMC), a tertiary level hospital Mwanza Tanzania. A total 380 were recruited interviewed by using Edinburg Postnatal Depression Scale. The sample size randomly selected...

Background: Guidelines for the treatment of HIV recommend use of immunological and clinical criteria monitoring in resource limited settings. Data on magnitude immunological failure sub-Saharan Africa is scarce. This study aimed at assessing and factors associated with among infected patients on HAART. Methods: A cross sectional was conducted Bugando Medical centre HIV care between February-July 2011, involving HIV-infected patients first line ART least one year. Patients...