A5007742847- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- HIV/AIDS Impact and Responses
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vaccine Coverage and Hesitancy
- Viral-associated cancers and disorders
- Blood Pressure and Hypertension Studies
- Diagnosis and treatment of tuberculosis
- Infection Control in Healthcare
- Blood donation and transfusion practices
- Infection Control and Ventilation
- Cardiac, Anesthesia and Surgical Outcomes
- Medication Adherence and Compliance
- HIV, Drug Use, Sexual Risk
- Tuberculosis Research and Epidemiology
- Viral Infections and Outbreaks Research
- Viral Infections and Vectors
- Blood groups and transfusion
- Histiocytic Disorders and Treatments
- Antibiotic Use and Resistance
- COVID-19 and healthcare impacts
Kilimanjaro Christian Medical Centre
2016-2025
Amref Health Africa
2015-2021
Culver Stockton College
2020
Western University of Health Sciences
2019
Health Foundation
2019
Moshi Co-operative University
2019
Christian Medical College & Hospital
2018
Catholic University of Health and Allied Sciences
2017
Tumaini University
2015-2017
Ifakara Health Institute
2015
Antibiotic dispensing without a prescription poses threat to public health as it leads excessive antibiotic consumption. Inappropriate availability the community has been documented be amongst drivers of antimicrobial resistance emergence. Community pharmacies are source antibiotics in low and middle-income countries (LMICs). We aimed at assessing practices by pharmacy retailers Moshi urban, Kilimanjaro, Tanzania recommend interventions improve practice. Using Simulated Client (SC) Method,...
A catheter-related bloodstream infection (CRBSI) is a life-threatening complication of hemodialysis. It responsible for significant morbidity and mortality costly long hospital stay. Despite its burden, little known about the factors associated with it antibiogram causative bacteria. This study aimed to evaluate determinants hemodialysis CRBSI appropriate isolated bacterial pathogens among patients attending KCMC unit. hospital-based retrospective analytical cross-sectional involved adult...
COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of clinical manifestations is influenced by dysregulated inflammatory response. Early identification the subclinical crucial for timely intervention improved patient outcomes. While there are various biomarkers to predict disease severity outcomes, their accessibility affordability pose challenges resource-limited settings. We explored potentiality neutrophil-to-lymphocyte ratio (NLR) as...
The coexistence of viral hepatitis with diabetes mellitus (DM) significantly escalates the risk severe outcomes. This study aimed to determine seroprevalence and associated factors B (HBV) C (HCV) infections among DM patients in northern Tanzania. Conducted between February 2023 May 2023, this hospital-based cross-sectional enrolled 189 from Diabetic Clinic Kilimanjaro Christian Medical Centre. A structured questionnaire captured relevant clinical information, plasma blood sample was...
Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The majority of infected people, including healthcare workers are unaware their status. This study aimed to determining seroprevalence hepatitis associated factors among northern Tanzania.This cross-sectional included 442 (HCWs) from tertiary teaching hospital Tanzania before nationwide vaccination campaign 2004. Questionnaire- based interviews were used obtain detailed...
Objective. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of diabetes mellitus (DM) and may progress to diabetic foot, which frequently leads amputation and/or disability death. Data scanty on the burden in Tanzania. The aim this study was assess neuropathy, its severity, associated factors. Methods. cross-sectional hospital-based carried out from October 2017 March 2018 among adolescent adult patients attending Kilimanjaro Christian Medical Center (KCMC) clinic....
Introduction . Although ART has improved the outcome of people living with HIV/AIDS, still some patients develop TB while receiving ART. The literature on magnitude this problem is scarce in our setting especially northwestern Tanzania. This study was designed to determine prevalence active among HIV and assess its potential risk factors. Methods A retrospective cohort done adult HIV-positive initiated at Bugando Medical Centre. Patients who were positive before initiation excluded. Data...
Crimean-Congo hemorrhagic fever is a tick-borne zoonotic disease that may be severe and present in many African countries. We aimed to understand the seroprevalence risk for virus Tanzania by testing archived serum samples from patients enrolled prospective cohort study.
Background Vitamin K antagonists (VKA) continue to be the principal anticoagulants for both treatment and prevention of venous thromboembolism. The use VKA often requires regular monitoring avoid over-anticoagulation prevent thromboembolic complications. aim was determine indication factors associated with suboptimal anticoagulation control among patients in northern Tanzania. Methods This a retrospective cohort study that examined data on long-term from 1 st January 2020 31 December 2022....
This study aims to determine the distribution of blood groups and demographic background donors in a referral hospital Northern Tanzania.The most common group was O (52.3%) least AB (3.18%). 97.7% were Rh positive rest negative. Most young adults, representing age 19-29. The majority male (88.1%) (90.8%) replacement while remainder voluntary donors.
Background . Microbial transmission from patient to has been linked transient colonization of health care workers attires. Contamination workers’ clothing including white coats may play a big role in microbes. Study Objective This study was conducted determine the type bacterial contamination on medical doctors and students associated factors. Methods A cross-sectional with purposive sampling undertaken. Demographic variables usage details were captured: when coat last washed, frequency...
Abstract Background Albumin is an important protein that transports hormones, fatty acids, and exogenous drugs; it also maintains plasma oncotic pressure. considered a negative active phase because decreases during injuries sepsis. In spite of other factors predicting surgical outcomes, the effect pre postoperative serum albumin to complications can be assessed by calculating percentage decrease in (delta albumin). This study aimed explore perioperative as predictor adverse outcomes major...
Self medication is a common practice of using medicines without medical supervision by the people themselves. likely to happen when feel unwell, it worse in population with poor helth seeking behavior. Therefore important assess prevalence and factors associated self antibiotics among University students Moshi, Kilimanjaro Tanzania.A cross sectional study was conducted from April-August 2019 at two Universities including one non medical. The were undergraduate aged 18 above, A self-filled...
Kaposi's sarcoma (KS) is a multifocal angioproliferative tumor involving blood and lymphatic vessels, caused by Human Herpes Virus-8 (HHV-8). KS an important AIDS-defining with high prevalence in Sub-Saharan Africa, including Tanzania which has HIV HHV-8 sero-prevalence. It critically to monitor the of tumors, such as KS, age HIV/AIDS. We studied associated risk factors among HIV-positive patients at Kilimanjaro Christian Medical Centre (KCMC), referral hospital northern Tanzania, over...
With a growing access to free ART, switching of ART second line regimen has also become common following failure first regimens. Patients failing on regimens have been shown stand high risk subsequent The magnitude those who are virologicaly is not documented in our setting. This study was designed assess the and correlates treatment failure. A retrospective analysis patients for at least 1 year done Bugando care center. Information demographic, clinical laboratory data were collected...
BackgroundPatients with diabetes mellitus are at high risk of cardiovascular events because abnormal lipid status.Dyslipidemia is common in and associated complications.Early diagnosis treatment the main cornerstone prevention its multiple complications.There scarcity data on magnitude factors dyslipidemia among diabetic patients Northern zone Tanzania. ObjectiveThe aim study was to determine prevalence profile levels attending clinic Kilimanjaro Christian Medical Centre, Moshi MethodologyA...
Abstract Background COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of clinical manifestations is influenced by dysregulated inflammatory response. Early identification the subclinical crucial for timely intervention improved patient outcomes. While there are various biomarkers to predict disease severity outcomes, their accessibility affordability pose challenges resource-limited settings. We explored potentiality neutrophil-to-lymphocyte...
Introduction: Tracking of blood glucose levels by patients and care providers remains an integral component in the management diabetes mellitus (DM). Evidence, primarily from high‐income countries, has illustrated effectiveness self‐monitoring (SMBG) controlling DM. However, there is limited data on feasibility impact SMBG among rural regions sub‐Saharan Africa. This study aimed at assessing SMBG, its adherence, associated factors effect glycaemic control insulin‐treated with DM northeastern...
PURPOSE This study sought to delineate the clinical, laboratory, and imaging characteristics during multiple myeloma (MM) diagnosis, outline treatment modalities administered, ascertain survival rates among patients with MM over a comprehensive 5-year span in Tanzania. METHODS retrospective cohort investigated diagnosed at Cancer Care Clinic, Kilimanjaro Christian Medical Centre, between January 2017 June 2022. Demographic data, clinical profiles, outcomes were collected. The employed...
Due to the expensiveness and unavailability of endoscopy management in Tanzania, outcomes variceal bleeding are unknown. The objective this study was assess patients with bleeding.
Introduction . Heart failure (HF) is characterized by frequent episodes of decompensation, leading to a high hospitalization burden. More than 50% index hospitalizations for HF patients return within 6 months discharge. Once the patient readmitted, risk further disease progression and mortality rate are increased. A lot readmitted due factors such as poor medication adherence, infections, or worsening comorbidities. The aim our study was identify inpatient burden readmission associated with...
Chorea is a rare complication of uncontrolled type II diabetes. We report for the first time in Tanzania case diabetes presenting with hyperglycaemia-induced hemichorea.
Bee sting has been identified as among causative agents of nephrotoxic acute tubular necrosis which may lead to kidney injury. envenomation medicinal properties but when a higher dose is inoculated cause severe anaphylaxis with very poor prognosis. We report 12-year-old boy injury following multiple bee stings who recovered well after hemodialysis.
In resource-limited settings, it is a challenge to get quality clinical specimens due poor infrastructure for their collection, transportation, processing and storage. Using dried blood spots (DBS) might be an alternative plasma HIV-1 drug resistance testing in this setting. The objectives of study were determine mutations associated with antiretroviral among children <18 months old born HIV-1-infected mothers enrolled prevention mother-to-child transmission services northern...