A5074865365- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Global Maternal and Child Health
- Peptidase Inhibition and Analysis
- Inflammatory Biomarkers in Disease Prognosis
- Healthcare Systems and Reforms
- Myasthenia Gravis and Thymoma
- Pituitary Gland Disorders and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Congenital Heart Disease Studies
- COVID-19 and healthcare impacts
- Multiple Myeloma Research and Treatments
- Hepatitis B Virus Studies
- Global Health and Epidemiology
- Cardiac Structural Anomalies and Repair
- Hepatocellular Carcinoma Treatment and Prognosis
- Thyroid Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Antimicrobial Resistance in Staphylococcus
- Gout, Hyperuricemia, Uric Acid
- Genetic Syndromes and Imprinting
- Heart Failure Treatment and Management
- Growth Hormone and Insulin-like Growth Factors
- Blood transfusion and management
Kilimanjaro Christian Medical Centre
2020-2025
Narayana Health
2024
A catheter-related bloodstream infection (CRBSI) is a life-threatening complication of hemodialysis. It responsible for significant morbidity and mortality costly long hospital stay. Despite its burden, little known about the factors associated with it antibiogram causative bacteria. This study aimed to evaluate determinants hemodialysis CRBSI appropriate isolated bacterial pathogens among patients attending KCMC unit. hospital-based retrospective analytical cross-sectional involved adult...
Background Vitamin K antagonists (VKA) continue to be the principal anticoagulants for both treatment and prevention of venous thromboembolism. The use VKA often requires regular monitoring avoid over-anticoagulation prevent thromboembolic complications. aim was determine indication factors associated with suboptimal anticoagulation control among patients in northern Tanzania. Methods This a retrospective cohort study that examined data on long-term from 1 st January 2020 31 December 2022....
COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of clinical manifestations is influenced by dysregulated inflammatory response. Early identification the subclinical crucial for timely intervention improved patient outcomes. While there are various biomarkers to predict disease severity outcomes, their accessibility affordability pose challenges resource-limited settings. We explored potentiality neutrophil-to-lymphocyte ratio (NLR) as...
The coexistence of viral hepatitis with diabetes mellitus (DM) significantly escalates the risk severe outcomes. This study aimed to determine seroprevalence and associated factors B (HBV) C (HCV) infections among DM patients in northern Tanzania. Conducted between February 2023 May 2023, this hospital-based cross-sectional enrolled 189 from Diabetic Clinic Kilimanjaro Christian Medical Centre. A structured questionnaire captured relevant clinical information, plasma blood sample was...
We aimed to determine the out-of-pocket (OOP) costs for medical care of injured patients and proportion encountering catastrophic costs.Prospective cohort study SETTING: Emergency department (ED) a tertiary-level hospital in Dar es Salaam, Tanzania.Injured adult seen at ED Muhimbili National Hospital from August 2019 March 2020.During alternating 12-hour shifts, consecutive trauma were approached after stabilisation. A case report form was used collect social-demographics patient clinical...
Abstract Background COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of clinical manifestations is influenced by dysregulated inflammatory response. Early identification the subclinical crucial for timely intervention improved patient outcomes. While there are various biomarkers to predict disease severity outcomes, their accessibility affordability pose challenges resource-limited settings. We explored potentiality neutrophil-to-lymphocyte...
Introduction: Tracking of blood glucose levels by patients and care providers remains an integral component in the management diabetes mellitus (DM). Evidence, primarily from high‐income countries, has illustrated effectiveness self‐monitoring (SMBG) controlling DM. However, there is limited data on feasibility impact SMBG among rural regions sub‐Saharan Africa. This study aimed at assessing SMBG, its adherence, associated factors effect glycaemic control insulin‐treated with DM northeastern...
PURPOSE This study sought to delineate the clinical, laboratory, and imaging characteristics during multiple myeloma (MM) diagnosis, outline treatment modalities administered, ascertain survival rates among patients with MM over a comprehensive 5-year span in Tanzania. METHODS retrospective cohort investigated diagnosed at Cancer Care Clinic, Kilimanjaro Christian Medical Centre, between January 2017 June 2022. Demographic data, clinical profiles, outcomes were collected. The employed...
There has been increasing evidence of the association between hyperuricemia and diabetes mellitus (DM). In general population, associated with pre-diabetes. DM patients, poor outcomes.
Due to the expensiveness and unavailability of endoscopy management in Tanzania, outcomes variceal bleeding are unknown. The objective this study was assess patients with bleeding.
Introduction . Heart failure (HF) is characterized by frequent episodes of decompensation, leading to a high hospitalization burden. More than 50% index hospitalizations for HF patients return within 6 months discharge. Once the patient readmitted, risk further disease progression and mortality rate are increased. A lot readmitted due factors such as poor medication adherence, infections, or worsening comorbidities. The aim our study was identify inpatient burden readmission associated with...
The burden of noncommunicable diseases is increasing in developing countries and settings with an existing communicable burden. study aim was to identify the disease pattern, length stay, clinical outcome medical admissions.
The availability of medical intensive care unit (MICU) services is limited, which the main obstacle to providing optimal critically ill patients. Describing disease patterns and clinical outcomes will help make better use limited resources. This retrospective study was conducted determine pattern outcome MICU admissions aid continuous quality improvement in obstetric care.This a tertiary hospital northeastern Tanzania. Data on participant characteristics were collected from patient records...
Background: Thyrotoxicosis is a clinical syndrome with high amounts of free thyroid hormone levels causing elevated function in body tissues. Prolonged effects hormones may lead to cardiac complications such as atrial fibrillation (AF) and heart failure (HF). Case 1: A 31-year-old female, was admitted due difficulty breathing, generalised swelling jaundice. She dyspnoeic an irregular rate, presented abnormal vitals, liver tests which were diagnostic for storm. managed over 32 days...
The current global pandemic caused by coronavirus has uncovered multiple symptoms, including sudden hearing loss in either one or both ears, with different outcomes. We present a 68-year-old female onset bilateral loss, fever, generalized body weakness, and gastrointestinal disturbances. She tested positive for severe acute respiratory syndrome 2, was isolated, treated variety of medications 5 days before being discharged home to self-isolate. audiological assessment revealed sensorineural...
Summary Myxedema coma is a severe complication of hypothyroidism, commonly affecting women over 60 years age, causing slow, progressive multi-organ dysfunction, and mental deterioration. Due to improved diagnostics treatment myxedema has become uncommon. However, it hardly reported in resource-limited settings. We present an elderly female with history total thyroidectomy due multi-nodular goiter. She presented features heart failure, excessive weight gain, cold sensation. Although the...
Summary Acromegaly is a rare disease caused by hypersecretion of the growth hormone (GH). Most cases are either pituitary microadenoma or macroadenoma. The GH producing tumors present with clinical manifestations acromegaly due to excessive secretion symptoms resulting from mass effects enlarging tumor. physical changes usually slow and, therefore, recognition delayed. These adenomas never malignant but can have significant morbidity and mortality. A subgroup patients severe hyperglycemia in...
Cardiac sarcomas are the predominant type of malignant primary cardiac tumors, especially in cases where patients <50 years age and have a poor prognosis, with 5-year survival rate less than 15%. angiosarcomas common sarcoma. angiosarcoma is highly aggressive tumour, approximately 75% originating right atrium, has higher incidence males females. The present case report describes 31-year-old woman who was initially suspected having tuberculous pericarditis treated anti-tuberculous...
Having an estimated level of Hb drop in different orthopedic surgeries would help plan for surgery from pre- to postoperative periods. The aim this study was assess the and associated factors during intraoperative period among elective surgeries.
Background Africa has consistently had the highest prevalence (70.1%) of H . pylori , and this led to significant cases dyspepsia, gastric cancers, upper gastrointestinal bleeding. However, most studies have used sero-prevalence, which might not give current state infection. Among tests, stool antigen test is simple, quick, effective. The study aimed determine feco-prevalence, endoscopic pattern, associated factors infection among symptomatic adult patients in Northern Tanzania. Materials...
Hydatid disease is an indolent parasitic infection caused by Echinococcus. The transmitted through the ingestion of uncooked, contaminated vegetables and can infect almost any human organ, commonly liver, followed lung, rarely heart. A computed tomography scan modality choice for identifying hydatid cysts, magnetic resonance imaging complications. definitive treatment includes surgery, with possible use antihelmintics in inoperable cases. To avoid fatal complications, must be treated as soon...
Purpose Chronic systemic inflammation from human immunodeficiency virus (HIV) may cause metabolic abnormalities in lipid metabolism. Additionally, the development of syndrome has been associated with specific anti-retroviral therapy, particularly dolutegravir. This study aimed to determine prevalence and factors among people living HIV on dolutegravir-based therapy. Methods was an analytical cross-sectional conducted between October 1, 2022, March 31, 2023, 312 HIV. A structured...
Introduction and importance: Thymomas present either concurrently with myasthenia gravis, local pressure symptoms, or asymptomatically as a mediastinal mass. Due to its variable presentation, the incidence is low, not all cases would be identified. can rare entity of combined T-cell B-cell immunodeficiency in adults. Thymectomy most important prognostic factor, including preventing autoimmune manifestations thymoma, but may persist after thymectomy. Case presentation: The authors report case...
Fibrosing mediastinitis (FM) is a rare cause of lung fibrosis with multiple etiologies ranging from infectious to autoimmune idiopathic. Common causes FM include histoplasmosis and relatively new IgG4-related disease. We present 55-year-old male symptoms esophageal varices, intractable hiccups, progressive difficulty in breathing. A chest X-ray showed right pleural effusion loss volume, which was originally thought be the sequelae SARS-CoV-2 or metastasis, but computed tomography revealed...