Several donor-specific factors influence the functional recovery and long-term outcomes of liver grafts. This study investigated association between donor fasting glucose (DFG) recipient after living transplantation (LDLT) in 950 cases at a single center. Patients were divided into two groups: low-DFG (< 85 mg/dL, n = 120) control (≥ 830). The five-year graft survival rate was significantly lower group (71.5%) compared to (80.0%) (P 0.02). Multivariable Cox regression analysis showed that...

Pre-transplantation red blood cell transfusion (RBCT) is a well-recognized cause of allosensitization. However, the effects RBCT after kidney transplantation remain controversial. This study evaluates impacts within first 30 days post-transplantation (early RBCT) with regard to long-term patient and graft outcomes. We retrospectively analyzed 785 patients who underwent HLA- ABO-compatible between 2014 2020. Patients were categorized based on whether they received early RBCT. Overall, 18.9%...

Carbapenem-resistant Acinetobacter baumannii bacteremia (CRAB-B) is a fatal infectious complication of liver transplantation (LT). This study investigated the incidence, effects, and risk factors associated with CRAB-B during early post-LT period. Among 1051 eligible LT recipients, 29 patients experienced within 30 days cumulative incidence 2.7%. In (n = 29) matched controls 145) by nested-case control design, death on 5, 10, from index date was 58.6%, 65.5%, 2.1%, 2.8%, 4.2%, respectively...

Death with a functioning graft is important cause of loss after kidney transplantation. However, little known about factors predicting death among transplant recipients. In this study, we evaluated the association between post-transplant creatinine-cystatin C ratio and in 1592 We divided patients into tertiles based on sex-specific ratio. Among recipients, 39.5% were female, 86.1% underwent living-donor The cut-off value for lowest tertile was 0.86 males 0.73 females. had significantly lower...

The risk factors for late-onset Pneumocystis jirovecii pneumonia (PCP) after liver transplantation (LT) have not been well studied. We aimed to analyze the clinical features preceding PCP in LT recipients that would guide individualized prophylaxis.Among 742 patients who underwent and routine prophylaxis from January 2009 through December 2019 at Severance Hospital, 27 developed PCP. conducted a retrospective case-control study matching each patient with four controls analyzed PCP.After 6...

Cytomegalovirus (CMV), a common pathogen, causes infectious complications and affects long-term survival after transplantation. Studies examining living donor liver transplantation (LDLT) are limited. This study analyzed the risk factors for CMV infection its impact on of LDLT patients. A nested case-control design retrospectively data from 952 patients who underwent 2005-2021. The incidence cohort was 15.2% at 3 months managed preemptively. Patients with infections were matched those...

The benefits of living-donor liver transplantation (LDLT) in patients with a high Model for End-stage Liver Disease (MELD) score (who have waitlist mortality) are unclear. Regional availability deceased-donor organs must be considered when evaluating LDLT benefits. authors aimed to compare the survival benefit intended-LDLT awaiting (DDLT) MELD greater than or equal 30 region severe organ shortage.This retrospective review included 649 placed on waitlist. They were divided into ( n =205)...

Seizures are a frequent neurological consequence following liver transplantation (LT), however, research on their clinical impact and risk factors is lacking. Using nested case-control design, patients diagnosed with seizures (seizure group) within 1-year post-transplantation were matched to controls who had not experienced until the corresponding time points at 1:5 ratio perform survival factor analyses. developed in 61 of 1,243 (4.9%) median 11 days after LT. Five-year graft was...

Statins have been reported to reduce overall death and hepatocellular carcinoma (HCC) recurrence in liver transplantation (LT) recipients. However, previous retrospective studies significant flaws immortal time bias.Using data from 658 patients who received LT for HCC, we matched 140 statin users with nonusers a 1:2 ratio at the of first administration after using exposure density sampling (EDS). The propensity score, calculated baseline variables (including explant pathology), was used EDS...

Abstract Background The Living Kidney Donor Profile Index (LKDPI) was developed in the United States to predict graft outcomes based on donor characteristics. However, there are significant differences demographics, access transplantation, proportion of ABO incompatibility, and posttransplant mortality Asian countries compared with States. Methods We evaluated clinical relevance LKDPI score a Korean kidney transplant cohort by analyzing 1860 patients who underwent transplantation between...

Background. Bacterial infections are major complications that cause significant mortality and morbidity in living donor liver transplantation (LDLT). The risk of bacterial infection has not been studied ABO-incompatible (ABOi) recipients with a desensitization protocol relation to the number plasma exchanges (PEs). Therefore, we aimed analyze ABOi LDLT high PEs compared low PEs. Methods. A retrospective study was performed 681 adult recipients, whom 171 were categorized into (n = 52) or 119)...

Previous studies reported suppressive effects of antiplatelet agents on hepatocellular carcinoma (HCC); however, this has never been assessed in patients who underwent liver transplantation (LT). This retrospective observational study used data from LT recipients with pre-transplant HCC a single tertiary hospital. The population was divided into two groups according to the use for >90 days within period (377 versus 91 non-antiplatelet groups). Matched containing 79 each group were also...

Background: This study aims to analyze the outcomes of living donor liver transplantation (LDLT) using grafts with multiple hepatic arteries (HAs), compared those a single HA.Methods: A retrospective analysis was conducted on 1,059 LDLT patients from July 2005 December 2022 at Severance Hospital, South Korea.Patients were categorized into multiple-HA and single-HA groups.Propensity score matching employed balance baseline characteristics, primary being graft survival secondary including HA,...

<title>Abstract</title> Background Pre-transplantation red blood cell transfusion (RBCT) is a well-recognized cause of allosensitization. However, the effects RBCT after kidney transplantation remain controversial. This study evaluates impacts within first 30 days post-transplantation (early RBCT) with regard to long-term patient and graft outcomes. Methods We retrospectively analyzed 785 patients who underwent HLA- ABO-compatible between 2014 2020. Patients were categorized based on whether...

Purpose: Autologous arteriovenous fistulas (AVFs) are considered the gold standard for hemodialysis access, with outcomes largely dependent on surgeon's experience.Nevertheless, few studies have been conducted learning curve of junior vascular surgeons in AVF creation.This study aims to address this by examining development surgical skills among surgeons.Materials and Methods: A retrospective analysis was 100 patients who underwent autologous procedures performed five between January 2018...

BACKGROUND Given that pregnancy is an immune-sensitizing event, female kidney transplant recipients who receive allografts from their offspring or husbands may have a higher risk of rejection and graft failure due to pre-sensitization acquired during childbirth. We investigated the association between donor relatedness (i.e., offspring, husband, unrelated) survival among living-donor (LDKT) with histories. MATERIAL AND METHODS From January 2009 2018, total 2060 LDKTs were performed at Asan...

The model for end-stage liver disease 3.0 (MELD3.0) is expected to address the flaws of current allocation system deceased donor transplantation (DDLT). We aimed validate MELD3.0 in Korean population where living predominant due organ shortages.Korean large-volume single-centric waitlist data were merged with Network Organ Sharing (KONOS) data. 90-day mortality was compared between MELD and using C-index 2,353 eligible patients registered transplantation. Patient numbers outcomes based on...

Abstract Purpose: Unusual grafts, including extended left liver plus caudate lobe, right anterior section, and posterior section are alternatives to lobe grafts for living-donor transplantation. This study aimed investigate unusual from the perspectives of recipients donors. Methods: From 2016 2021, 497 patients received transplantation at Severance Hospital. Among them, 10 grafts. Three two five Liver volumetrics anatomy were analyzed all We collected data on laboratory examinations...

Unusual grafts, including extended left liver plus caudate lobe, right anterior section, and posterior section are alternatives to lobe grafts for living-donor transplantation. This study aimed investigate unusual from the perspectives of recipients donors.From 2016 2021, 497 patients received transplantation at Severance Hospital. Among them, 10 grafts. Three two five Liver volumetrics anatomy were analyzed all donors. We collected data on laboratory examinations (alanine aminotransferase,...

Background: Seizure is one of the most common neurological complications liver transplantation (LT).However, clinical impact and risk factors for seizures after LT have not been sufficiently investigated.This study evaluated LT.Methods: The data patients who underwent in a single tertiary hospital were analyzed using nested case-control design.Patients diagnosed with (seizure group) within 1-year posttransplantation matched to controls had experienced until corresponding time points at 1:5...

Background: Human leukocyte antigen (HLA) plays a crucial role in the immune response through recognition.Homozygosity at HLA loci may lead to reduced immunosurveillance and an increased risk of malignancy.However, impact diversity on de novo malignancy kidney transplant recipients has not been thoroughly assessed.Methods: We conducted retrospective analysis 2,157 adult who underwent transplantation Severance Hospital between 2006 2020.To address diverse timeframes for occurrence after...

Background:The liver regulates glucose metabolism through a balance of uptake and the release glucose.After receiving from donor with low fasting glucose, there is an increased risk graft failure.However, no information has been disclosed about living donors outcome after transplantation (LDLT).Methods: In this retrospective study single centric data, total 851 LDLT patients were divided into two groups according to level donor; <85 mg/dL (low-donor [DFG], n=106) 85 (control group,...

Cytomegalovirus infection is the most common viral among liver transplant recipients.ABO incompatibility considered a risk factor for cytomegalovirus because of need desensitization and immunosuppression.Whether ABO-incompatible living donor transplantation associated with an increased incidence remains controversial.We analyzed 630 patients who underwent between 2012 2021 at Severance Hospital.Patients were younger than 18 years age, died or repeat within 30-day period, combined organ...