A5053473595- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Prostate Cancer Treatment and Research
- Management of metastatic bone disease
- Meningioma and schwannoma management
- Sarcoma Diagnosis and Treatment
- Radiation Dose and Imaging
- Effects of Radiation Exposure
- Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- Cancer and Skin Lesions
- Lung Cancer Treatments and Mutations
- Radiation Therapy and Dosimetry
- Cancer Treatment and Pharmacology
- Tumors and Oncological Cases
- Nuclear and radioactivity studies
- Nonmelanoma Skin Cancer Studies
- Neurofibromatosis and Schwannoma Cases
- Radiomics and Machine Learning in Medical Imaging
Wolters Kluwer Health
2023
Crozer-Keystone Health System
2010-2020
Drexel University
2012-2017
Delaware County Memorial Hospital
2011-2016
Hospital of the University of Pennsylvania
2012
Pennsylvania Hospital
2012
Temple University
2012
Hahnemann University Hospital
2012
University of Wisconsin–Madison
1995-1998
University of North Carolina at Chapel Hill
1995
The low alpha/beta ratio of prostate cancer suggests that hypofractionated schemes dose-escalated radiotherapy should be advantageous. We report our experience using stereotactic body radiation therapy (SBRT) for the primary treatment to assess efficacy and toxicity.From 2007 2010, 70 patients (51 % risk, 31 intermediate 17 high risk) with localized were treated SBRT CyberKnife system. One-third received androgen deprivation therapy. Doses 37.5 Gy (n = 29), 36.25 36), 35 5) administered in...
Few studies have evaluated re-irradiation of lung cancer recurrences with stereotactic body radiotherapy (SBRT). This study evaluates outcomes SBRT for recurrent cancer.Two hundred and seventy-eight patients treated were retrospectively reviewed. Of those, 26 29 tumors re-irradiated SBRT. Ninety percent received prior external beam irradiation 10 % Previous median radiation dose was 61.2 Gy a 8-month interval from previous radiation. The 30 (48 Gy10 biological effective (BED)). Endpoints...
We present our initial experience with CyberKnife stereotactic body radiation therapy (SBRT) in a heavily pretreated group of patients liver metastases and primary tumors. From October 2007 to June 2009, 48 were treated at the Philadelphia Center for or report on 30 41 discrete lesions (1-4 tumors per patient) who received an ablative dose (BED ≥ 79.2 Gy10 = 66 Gy EQD2). The treatment goal was achieve high SBRT tumor while sparing least 700 cc from doses above 15 Gy. Twenty-three metastatic...
The current standard of care for salvage treatment glioblastoma multiforme (GBM) is gross total resection and adjuvant chemoradiation operable patients. Limited evidence exists to suggest that any particular modality improves survival recurrent GBM, especially if inoperable. We report our experience with fractionated stereotactic radiotherapy (fSRT) without chemo/immunotherapy, identifying prognostic factors associated prolonged survival.From 2007 2014, 19 patients between 29 78 years old...
Purpose: To define prognostic factors associated with improved survival and local control for gynecologic cancer recurrences limited to the pelvis para-aortic region using stereotactic body radiation therapy (SBRT). Methods: Between 2/2008 7/2014, 30 women (35 targets) pelvic or PA recurrence of endometrioid (n=12), cervical (n=11), ovarian (n=3), uterine serous (n=2) carcinosarcoma CA were treated SBRT. Eleven located in central pelvis(CP), 11 along sidewall(PSW), 13 (PA)region. Results:...
To evaluate acute toxicity outcomes of prostate cancer patients treated with CyberKnife-delivered hypofractionated radiotherapy.This study was a retrospective chart review analysis the first 50 CyberKnife radiotherapy for cancer. Most were affected early to intermediate stage Two had metastatic disease at presentation and excluded. A total 37 received irradiation dose 35 37.5 Gy in 5 fractions 7 7.5 per fraction. Assuming an alpha/beta ratio 1.5 Gy, this process delivered equivalent 85 96 2...
Purpose: To report an update of our previous experience using stereotactic body radiation therapy (SBRT) for the primary treatment prostate cancer, risk stratified by updated NCCN version 2.2014, reporting efficacy and toxicity in a community hospital setting. Methods: From 2007 to 2012, 142 localized cancer patients were treated with SBRT CyberKnife. guidelines Version 2.2014 groups analyzed included very low (20%), (23%), intermediate (35%), high (22%) risk. further explore group...
OBJECTIVES: The primary objective of this study is to compare freedom from biochemical failure (FFBF) between SBRT and IMRT for patients with organ confined prostate cancer treated 2007 through 2012 utilizing the 2015 National Comprehensive Cancer Network (NCCN) risk stratification guidelines. A secondary our updated toxicity at last follow up compared pretreatment respect bowel, bladder, sexual functioning, need invasive procedures two groups. METHODS: We retrospectively reviewed 270...
Oligometastatic prostate cancer is a limited metastatic disease state in which potential long-term control still possible with the use of targeted therapies such as surgery or stereotactic body radiation therapy (SBRT). SBRT may well potentially prolong time before initiation androgen deprivation (ADT) and docetaxel chemotherapy for oligometastatic cancer. The goal this study to outline prognostic factors associated improved outcome quantify effect prior systemic treatments ADT on survival...
Stereotactic ablative body radiotherapy (SABR) provides a superior non-small cell lung cancer (NSCLC) treatment option when compared to conventional for patients deemed inoperable or refusing surgery. This study retrospectively analyzed the rates of tumor control and toxicity following SABR (Cyberknife system) primary early-stage NSCLC in community setting.One hundred were treated between 2007 2011. Patients with T3-4 N1-3 disease, metastasis, recurrent local non-lung excluded from analysis....
Lung reirradiation for nonsmall cell lung cancer (NSCLC) is common either recurrent disease or new primary cancer. Dose volume tolerance of the after multiple courses radiation therapy (RT) unknown. We review our experience with patients NSCLC in a single community setting using stereotactic body (SBRT) to report cumulative doses, survival, and toxicity.Forty-four who received at least 2 curative RT second course delivered between January 2012 December 2017 were eligible. All had treated...
Stereotactic body radiation therapy (SBRT) is an attractive option for prostate cancer due to its short treatment duration and cost. In this report, we compare the efficacy toxicity outcomes of patients treated with SBRT those who received intensity-modulated (IMRT).Two hundred sixty-three localized adenocarcinoma were included, ranging from clinically very low- high-risk groups. We retrospectively consecutive conventionally fractionated IMRT. For most patients, was delivered a total dose...
The objective of the present study is to analyze prognostic factors affecting survival patients receiving stereotactic radiosurgery (SRS) for second brain metastatic event (SBME) following initial treatment with whole irradiation (WBI), surgical resection, or previous SRS. 88 treated SRS SBME at Philadelphia CyberKnife between January 2006 and October 2013 were included in group. Cox proportional-hazards regression was used identify that significantly impacted from time SBME. Independent...