- Photosynthetic Processes and Mechanisms
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- French Historical and Cultural Studies
- Historical Studies and Socio-cultural Analysis
- Enzyme Structure and Function
- Enzyme Catalysis and Immobilization
- Homicide, Infanticide, and Child Abuse
- Steroid Chemistry and Biochemistry
- Death, Funerary Practices, and Mourning
- Metal-Catalyzed Oxygenation Mechanisms
- Peptidase Inhibition and Analysis
- RNA and protein synthesis mechanisms
- Photoreceptor and optogenetics research
- Algal biology and biofuel production
- Legume Nitrogen Fixing Symbiosis
- Enzyme Production and Characterization
- Biochemical and Molecular Research
Ruhr University Bochum
2017-2024
United States Holocaust Memorial Museum
2022
In any given organism, approximately one-third of all proteins have a yet-unknown function. A widely distributed domain unknown function is DUF1127. Approximately 17,000 with such an arginine-rich are found in 4,000 bacteria. Most them single-domain proteins, and large fraction qualifies as small fewer than 50 amino acids. We systematically identified characterized the seven DUF1127 members plant pathogen Agrobacterium tumefaciens They give rise to authentic differentially expressed shown at...
Oxygenic phototrophs frequently encounter environmental conditions that result in intracellular energy crises. Growth of the unicellular green alga Chlamydomonas reinhardtii hypoxia light depends on acclimatory responses which induction photosynthetic cyclic electron flow is essential. The microalga cannot grow absence molecular oxygen (O2 ) dark, although it possesses an elaborate fermentation metabolism. Not much known about how senses and signals lack O2 or its survival strategies during...
The assembly of large, multi-cofactor membrane protein complexes like photosystem II (PSII) requires a high level coordination. process is facilitated by large network auxiliary proteins that bind transiently to unassembled subunits, preassembled modules or intermediate states PSII, which are comprised subset subunits. However, analysis these immature, partially assembled PSII hampered their low abundance and intrinsic instability. In this study, was purified from the thermophilic...
The pharmaceutical industry has developed various highly effective semi-synthetic cephalosporins, which are generated by modifying the side chains of core molecule 7-aminocephalosporanic acid (7-ACA). In industrial productions, 7-ACA nucleus is obtained in vitro from cephalosporin C (CPC) chemical or enzymatic processes, waste intensive and associated with high production costs. Here, we used a transgenic vivo approach to express bacterial genes for acylase (CCA) CPC producer Acremonium...
Abstract The synthesis of multi-span thylakoid membrane proteins initiates at ribosomes off the membrane. Subsequently, ribosome nascent chain complexes (RNCs) are transferred to translocase machinery in for cotranslational protein insertion. These steps require finely tuned mechanisms processing, quality control, and targeting prevent misfolding or aggregation ensure efficient transfer insertion machinery. However, little is known about regulatory network underlying these processes. To...
Abstract The multi-subunit membrane protein complex Photosystem II (PSII) catalyzes the light-driven oxidation of water and with this initial step photosynthetic electron transport in plants, algae, cyanobacteria. Its biogenesis is coordinated by a network auxiliary proteins that facilitate stepwise assembly individual subunits cofactors, forming various intermediate complexes until fully functional mature PSII present at end process. In current study, we purified from mutant line...
Les services d'immigration ont longtemps conservé des territoires spéciaux, détenant parfois les nouveaux arrivants pendant mois, voire années. L'un de ces – l'iconique Ellis Island dans le port New York a servi depuis années 1920 lieu pour détenir radicaux d'origine étrangère et point départ nombre d'expulsions. longues périodes détentions à la fois bouleversé renforcé identités éventuels immigrants. Ce article examine expériences Norbert Wollheim, retenu, au début Guerre froide, comme...
During the Nazi era, role and boundaries of Jewish cemeteries underwent profound change. The places where Jews could grieve honor their dead were utterly ransacked. This article focuses primarily on upheavals that occurred in Reich’s under regime. It then deals with a post-war conflict Fulda JRSO, major restitution organization, fought to recover town’s former cemetery its entirety. history such institutions, both era decades following 1945, raises broad questions about how we understand...