A5080769534- Inflammatory Bowel Disease
- Microscopic Colitis
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Gastrointestinal disorders and treatments
- Diagnosis and treatment of tuberculosis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Diverticular Disease and Complications
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Pregnancy and Medication Impact
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Radiomics and Machine Learning in Medical Imaging
- Biosimilars and Bioanalytical Methods
- Genetic factors in colorectal cancer
- Pancreatitis Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Helicobacter pylori-related gastroenterology studies
- Liver Diseases and Immunity
- Vitamin D Research Studies
- Immunodeficiency and Autoimmune Disorders
- Celiac Disease Research and Management
Chulalongkorn University
2016-2025
King Chulalongkorn Memorial Hospital
2015-2025
Thai Red Cross Society
2014-2023
Bangkok Hospital
2022
Mayo Clinic in Arizona
2017-2021
Mayo Clinic
2017-2020
Thai Health Promotion Foundation
2020
Weatherford College
2020
WinnMed
2017-2019
Mayo Clinic in Florida
2018
<h3>Objective</h3> The rising incidence of inflammatory bowel disease in Asia supports the importance environmental risk factors aetiology. This prospective population-based case-control study Asia-Pacific examined prior to patients developing IBD. <h3>Design</h3> 442 incident cases (186 Crohn9s (CD); 256 UC; 374 Asians) diagnosed between 2011 and 2013 from eight countries Australia 940 controls (frequency-matched by sex, age geographical location; 789 completed an factor questionnaire at...
Living in an urban environment may increase the risk of developing inflammatory bowel disease (IBD). It is unclear if this observation seen globally. We conducted a population-based study to assess relationship between urbanization and incidence IBD Asia-Pacific region.Newly diagnosed cases 2011 2013 from 13 countries or regions were included. Incidence was calculated with 95% confidence interval (CI) pooled using random-effects model. Meta-regression analysis used rates their association...
This study sought to re-estimate the cumulative incidence of perianal or rectovaginal fistulas and associated proctectomy rate in prebiologic era vs biologic using a population-based cohort Crohn’s disease (CD) patients. The medical records 414 residents Olmsted County, Minnesota, who were diagnosed with CD between 1970 2010 reviewed. from time diagnosis date first fistula estimated Kaplan-Meier method. Eighty-five patients (20.5%) had at least 1 episode January 1, 1970, June 30, 2016. was...
Although inflammatory bowel disease (IBD) has been more predominant in white populations, an increasing incidence of IBD nonwhites reported. We sought to evaluate the rates and temporal trends by race ethnicity.The resources Rochester Epidemiologic Project were used identify 814 county residents newly diagnosed with from 1970 through 2010. Race was categorized into whites nonwhites. Ethnicity Hispanic non-Hispanic. Incidence estimated adjusted for age sex 2010 United States (US) population....
Adenoma detection rate (ADR) cannot distinguish between endoscopists who detect one adenoma and those ≥2 adenomas. Hypothetically, miss (AMR) may be significant for with high ADRs examine the rest of colon less care after detecting first polyp. Our objective was to evaluate other quality indicators plus ADR vs. alone in prediction AMR.We conducted a cross-sectional study asymptomatic participants aged 50-75 years underwent back-to-back screening colonoscopies by four faculty endoscopists....
There are few real-world data on the safety of vedolizumab for treatment Crohn's disease (CD) or ulcerative colitis (UC). We quantified rates and identified factors significantly associated with infectious non-infectious adverse events in clinical practice.We performed a retrospective review from multicenter consortium database (from May 2014 through June 2017). Infectious were defined as those requiring antibiotics, hospitalization, discontinuation, resulting death. Rates proportions per...
Background & AimsWe created and validated a clinical decision support tool (CDST) to predict outcomes of vedolizumab therapy for ulcerative colitis (UC).MethodsWe performed logistic regression analyses data from the GEMINI 1 trial, 620 patients with UC who received induction maintenance (derivation cohort), identify factors associated corticosteroid-free remission (full Mayo score 2 or less, no subscore above 1). We used these develop model treatment, which we called CDST. evaluated...
Background & AimsPatients with Crohn's disease (CD), but not ulcerative colitis (UC), of shorter duration have higher rates response to tumor necrosis factor (TNF) antagonists than patients longer duration. Little is known about the association between and other biologic agents. We aimed evaluate CD or UC vedolizumab, stratified by duration.MethodsWe analyzed data from a retrospective, multicenter, consortium (n = 650) 437) treated vedolizumab May 2014 through December 2016. Using time event...
Abstract Background There is a rapid increase in the incidence of inflammatory bowel diseases (IBD) newly industrialized countries, yet epidemiological data incomplete. We herein report methodology adopted to study IBD countries and evaluate effect environmental factors including diet on development. Methods Global Visualization Epidemiology Studies 21st Century (GIVES-21) population-based cohort diagnosed persons with Crohn’s disease ulcerative colitis Asia, Africa, Latin America be...
Abstract Background: Negative results of EUS‐FNA for solid pancreatic lesions (SPL) can be false ones. Combination with strain ratio (SR) may ensure a correct benign diagnosis SPL. Aims: We prospectively evaluated the sensitivity rate and EUS elastography using method diagnosing Methods: Thirty‐eight patients SPL identified by CT or MRI between January 2013 November were included in our prospective study. diagnoses made SR an endosonographer who was blinded to all clinical information. In...
Several studies have suggested significant associations between environmental factors and the risk of developing inflammatory bowel disease [IBD]. However, data supporting role antibiotics are conflicting. The aim this study was to evaluate association antibiotic use new-onset IBD. We conducted a population-based case-control using Rochester Epidemiology Project Olmsted County, Minnesota. identified 736 county residents diagnosed with IBD 1980 2010 who were matched 1472 controls, based on...
We aimed to compare safety and effectiveness of vedolizumab tumor necrosis factor (TNF)-antagonist therapy in ulcerative colitis routine practice.A multicenter, retrospective, observational cohort study (May 2014 December 2017) patients treated with or TNF-antagonist therapy. Propensity score weighted comparisons for development serious adverse events achievement clinical remission, steroid-free deep remission. A priori determined subgroup TNF-antagonist-naïve -exposed patients, against...
Effects of linked-color imaging (LCI) on colorectal lesion detection and colonoscopy quality remain controversial. This study compared the rates adenoma other precursor lesions using LCI vs white-light (WLI) during screening, diagnostic, surveillance colonoscopies.This randomized controlled trial was performed at 11 institutions in 4 Asian countries/regions. Patients with abdominal symptoms, a primary screening colonoscopy, positive fecal immunochemical test results, or undergoing...
Introduction: Controversy remains regarding transparent cap-assisted technique improves adenoma detection rate (ADR) in colonoscopy. We aimed to investigate the effect of colonoscopy on ADR and other performance. Methods: performed sub-analysis an international, multicenter, open-label database containing data from 11 centers 4 Asian countries/regions patients who underwent The patient characteristics, procedure related pathological findings all detected lesions were prospectively recorded....
Clinical guidelines typically endorse conventional therapies such as 5-aminosalicylic acid (5-ASA) the mainstay of ulcerative colitis management. However, degree adoption and application guideline recommendations by physicians within Asia remains unclear. This study aims to understand prescribing patterns 5-ASA implementation current across Asian clinical practice. A physician survey was conducted among inflammatory bowel disease specialists in 8 territories practices preferences management,...
While performing a colonoscopy, there are many tasks to be done: finding polyps, classifying them, and deciding the next procedure for whether incise them or not. Such challenging fellow doctors. All these three can have an intrapersonal error, which varies among endoscopists. A proven method enhancing performance is computer-aided detection diagnosis system endoscopists, tends real-time system. In this work, we present modified convolutional neural network (CNN) based deep learning (DL)...
Abstract Background Mucosal histological activity is increasingly valued as a treatment endpoint in inflammatory bowel diseases (IBD). In the Asia Pacific region, however, utility and acceptability of IBD histology uncertain due to heterogeneity prevalence, resourcing, level knowledge among practitioners. There an opportunity engage clinicians harmonise reporting collaborate with pathologists this field. To end, we developed statements determine their consensus through anonymous voting on...
The clinical utility of vedolizumab (VDZ) trough levels (VTLs) in inflammatory bowel disease (IBD) is not well defined. aims this study are to determine the median VTLs and frequency detected antibodies, correlation with C-reactive protein (CRP) mucosal healing (MH), change management based on VTLs.A cross-sectional IBD patients treated VDZ checked between July 1, 2016, March 2017, was conducted. Mucosal defined as absence ulcers Crohn's (CD) Mayo endoscopic score ≤1 for ulcerative colitis...
Inflammatory bowel disease (IBD) is emerging in the newly industrialized countries of South Asia, South-East and Middle East, yet epidemiological data are scarce.We performed a cross-sectional study IBD demographics, phenotype, treatment across 38 centers 15 East. Intergroup comparisons included gross national income (GNI) per capita.Among 10 400 patients, ulcerative colitis (UC) was twice as common Crohn's (CD), with male predominance (UC 6678, CD 3495, unclassified 227, 58% male). Peak age...