Than Than Aye

ORCID: 0000-0003-1521-0660
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Diabetes Management and Education
  • Liver Disease Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Diabetes Management and Research
  • Inflammatory Bowel Disease
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Gastroesophageal reflux and treatments
  • Diabetes Treatment and Management
  • Gallbladder and Bile Duct Disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Clostridium difficile and Clostridium perfringens research
  • Chronic Disease Management Strategies
  • Veterinary medicine and infectious diseases
  • Esophageal Cancer Research and Treatment
  • Renal Diseases and Glomerulopathies
  • Galectins and Cancer Biology
  • Complementary and Alternative Medicine Studies
  • Pregnancy and Medication Impact
  • Gestational Diabetes Research and Management
  • Obesity and Health Practices

University Of Medicine 1 Yangon
2012-2025

University of Medicine 2 Yangon
2013-2024

Yangon Children's Hospital
2024

Heidelberg University
2024

Heidelberg University
2024

University Hospital Heidelberg
2024

East Yangon General Hospital
1975-2023

Hochschule Düsseldorf University of Applied Sciences
2022

Sheikh Shakhbout Medical City
2022

Yamamoto Hospital
2022

Diabetes is the ninth leading cause of death in women globally. In South Asians mortality with diabetes stands second highest. There a marked gender discrimination which faced by across Asia esp access to services and support for diabetes, resulting high rates morbidity diabetes. The most important risk factor identified epidemic obesity along genetic susceptibility. Lack health care, social cultural disparity, at work, disparity marriage, restricted medical facilities are prevalent....

10.4103/2230-8210.113720 article EN cc-by-nc-sa Indian Journal of Endocrinology and Metabolism 2013-01-01

Inflammatory bowel disease (IBD) is emerging in the newly industrialized countries of South Asia, South-East and Middle East, yet epidemiological data are scarce.We performed a cross-sectional study IBD demographics, phenotype, treatment across 38 centers 15 East. Intergroup comparisons included gross national income (GNI) per capita.Among 10 400 patients, ulcerative colitis (UC) was twice as common Crohn's (CD), with male predominance (UC 6678, CD 3495, unclassified 227, 58% male). Peak age...

10.1111/jgh.15801 article EN Journal of Gastroenterology and Hepatology 2022-02-17

Abstract Helicobacter pylori disturbs the stomach lining during long-term colonization of its human host, with sequelae including ulcers and gastric cancer 1,2 . Numerous H. virulence factors have been identified, showing extensive geographic variation 1 Here we identify a ‘Hardy’ ecospecies that shares ancestry ‘Ubiquitous’ from same region in most genome but has nearly fixed single-nucleotide polymorphism differences 100 genes, many which encode outer membrane proteins host interaction...

10.1038/s41586-024-07991-z article EN cc-by Nature 2024-10-16

ABSTRACT Background Dyspepsia is associated with a variety of benign and malignant gastrointestinal diseases. The aim the study was to evaluate spectrum upper endoscopic findings in patients presenting dyspepsia. Methods This retrospective on consecutive dyspepsia undergoing endoscopy at gastroenterology department Thingangyun General Hospital, University Medicine 2, Yangon, from January 1, 2017, December 31, 2019. Results In this study, 1650 were recruited retrospectively. Forty‐nine...

10.1002/jgh3.70121 article EN cc-by-nc-nd JGH Open 2025-02-01

Abstract A survey of 350 farmers was conducted in the lowland rainfed agricultural system central Myanmar (Burma) to examine importance rodents, farmers' perception causes yield loss, and their beliefs as why they undertake rodent management. Farmers grew monsoon rice, summer rice mungbeans with major constraints upon production identified pests (29.4% respondents), followed by insufficient water (19.4%). The main were insects (48.6%), rats (40.9%); however, thought that caused most damage...

10.1080/09670870701474047 article EN International Journal of Pest Management 2007-12-06

Abstract Myanmar is a country with significant administrative and natural divisions. Access to health-care in few parts adversely affected by socio-economic as well infrastructural development. With the prevalence of more than 10%, diabetes needs special attention including psycho-social management. Major challenges public health seeking behavioral issues, presence traditional medicine, life-style diet issues pertaining religion environmental was studied current study find out ways for...

10.4103/2321-0656.120255 article EN cc-by-nc-nd Journal of Social Health and Diabetes 2013-10-23

Differences in the Helicobacter pylori infection rate are not sufficient to clarify dissimilarity of gastric cancer incidence between Myanmar and its neighboring countries. To better understand this trend, H. virulence gene cagA was characterized Myanmar.Glutamate-proline-isoleucine-tyrosine-alanine (EPIYA) patterns CagA multimerization (CM) motifs genotypes were examined by performing polymerase chain reactions DNA sequencing.Of 69 tested strains, cagA-positive patients had significantly...

10.5009/gnl17053 article EN cc-by-nc Gut and Liver 2017-10-26

10.1016/s0009-9260(75)80051-1 article EN Clinical Radiology 1975-01-01

Background Helicobacter pylori BabA is an important outer membrane protein that involves in the attachment to gastric mucosa and enhances virulence property of bacterium. This study was aimed characterize bab genotypes, evaluate its association with cagA, vacA clinical diseases as well degree inflammation. Methods H. isolates from four countries were subjected for characterization bab. The locus specific forward reverse primers used get products by PCR, which could distinguish three (A, B...

10.1371/journal.pone.0187225 article EN cc-by PLoS ONE 2017-11-06

Approximately half of all births globally occur in the Asia Pacific Region. Concerted efforts to support local activities aimed at developing national newborn screening (NBS) have been ongoing for almost 30 years, first by International Atomic Energy Agency (IAEA) and then through volunteer efforts. Sustainable bloodspot continues be initiated develop many countries with economies region. Since discontinuation IAEA funding 2007, a working group Society Human Genetics (APSHG) consisting...

10.3390/ijns11010002 article EN cc-by International Journal of Neonatal Screening 2024-12-30

The present study explored the differences in gastric microbiome between three distinct populations of Southeast Asia. These include isolated Orang Asli population and modern Malaysians, as well patients from Myanmar, least developed country region. All 79 subjects recruited this had Helicobacter pylori infection. Based on alpha diversity analysis, richest most diverse microbiome, followed by Myanmar Malaysian groups. Beta analysis revealed significant separation samples different...

10.3390/microorganisms7060174 article EN cc-by Microorganisms 2019-06-14

Objectives Three subcategories of high‐risk flat and depressed lesions (FDLs), laterally spreading tumors non‐granular type (LST‐NG), lesions, large sessile serrated (SSLs), are highly attributable to post‐colonoscopy colorectal cancer (CRC). Efficient organized educational programs on detecting FDLs lacking. We aimed explore whether a web‐based intervention with training FIND clues (fold deformation, intensive stool/mucus attachment, no vessel visibility, demarcated reddish area) may...

10.1111/den.14244 article EN Digestive Endoscopy 2022-02-04

Background Although endoscopic ultrasound (EUS) features and criteria have been described in chronic pancreatitis, challenges remain with interoperator variability ease of adoption. The aim this study was to define validate the EUS pancreatitis a multicenter prospective Asia. Method divided into two parts: first part conducted derive adequate agreement; second prospectively evaluate these cross-sectional determine optimal combination for diagnosis pancreatitis. Prospectively enrolled cases...

10.1055/a-1217-3112 article EN cc-by-nc-nd Endoscopy 2020-07-10

Multidrug-resistant Helicobacter pylori strains are emerging in Southeast Asia. This study evaluates the region's real-world practice H. management.Physicians who managed eradication daily across 10 Asian countries were invited to participate an online questionnaire, which included questions about local availability of antimicrobial susceptibility tests (ASTs) and their preferred regimens practice. An empiric regimen was considered inappropriate if it did not follow guidelines/consensus,...

10.1111/hel.13018 article EN Helicobacter 2023-08-27

Osteoporosis is a disease in which the density and quality of bone are reduced, leading to weakness skeleton increased risk fracture, particularly spine, wrist hip. Generally, osteoporosis Myanmar still neglected entity national priority health problems. Due low level awareness on its consequent fragility fractures, limited availability accessibility standard diagnostic tools medications, mainly under diagnosed under-treated daily clinical practice. It not mentioned prioritized diseases plan.

10.15605/jafes.027.02.03 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2012-11-30
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