A5068376019- Diabetes and associated disorders
- Diabetes Management and Research
- Public Health and Nutrition
- Pancreatic function and diabetes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diet and metabolism studies
- Thyroid Disorders and Treatments
- Sexual Differentiation and Disorders
- Diet, Metabolism, and Disease
- Growth Hormone and Insulin-like Growth Factors
- Childhood Cancer Survivors' Quality of Life
- Neonatal Respiratory Health Research
- Healthcare Quality and Satisfaction
- COVID-19 Prevention and Impact
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neonatal Health and Biochemistry
- Adrenal Hormones and Disorders
- Dietary Effects on Health
- Connective tissue disorders research
- Digestive system and related health
- Human Health and Disease
- Hip and Femur Fractures
- Metabolism and Genetic Disorders
- Child and Adolescent Health
- Hormonal Regulation and Hypertension
Airlangga University
2013-2025
Indonesian Pediatric Society
2024
Universitas Dr. Soetomo
2022-2024
Bridge University
2023
Manchester Metropolitan University
2023
Association of Southeast Asian Nations
2015
Diagnosis of Adrenal Insufficiency (AI) in children is often challenging due to the relatively low incidence and non-specific presentation, so misdiagnosis occurs, especially emergency settings. Prompt recognition management are crucial reducing morbidity mortality linked this potentially fatal illness, emphasizing importance heightened awareness among healthcare professionals. A 9-month-old girl was brought ER with a chief complaint excessive vomiting. The presented hyperpigmentation,...
(1) Background: This study is designed to establish thyroid-stimulating hormone (TSH) reference intervals tailored different neonatal age groups and Indonesian local populations. (2) Methods: Dried blood spot TSH values, from 1 January 2022 31 December 2023, were used the partitioned by sex, gestational age, ethnic group at ages. (3) Results: A significant difference in value was observed ages, parental ethnicity subgroups (p < 0.05). Male significantly higher than those of females all...
Hyperglycemic Hyperosmolar State (HHS) is a triad characterized by severe hyperglycemia, significantly increased serum osmolality, and dehydration without marked ketoacidosis. It occurs in patients with both Type 1 2 Diabetes Mellitus. This case report discusses 7-year 9-month-old girl who presented to the hospital shortness of breath acidosis evidence ketonemia. The patient was moderately malnourished had experienced urinary frequency over past month. On examination, she alert but dry...
The expansion of newborn screening (NBS) for congenital hypothyroidism (CH) is essential to reducing the number preventable intellectual disabilities in children. Because logistical issues, including geographic extremes, distinct cultures, and 4.8 million births annually, Indonesia has struggled achieve universal NBS coverage. A national cross-sectional electronic survey was conducted explore challenges CH NBS. Responses from 423 healthcare professionals program administrators across 30...
The coronavirus-19 (COVID-19) pandemic requires the use of online media to ensure monitoring type 1 diabetes mellitus (T1DM) in children. Thus, this study aims determine whether education effectively improves quality life (QoL) children with T1DM during pandemic.The study, conducted from March October 2020, utilized paired t-test before and after education. Moreover, it adopts recommended Pediatric Quality Life Inventory (PedsQL) 3.2 module for 33 patients registered Endocrine Outpatient...
Type 1 diabetes mellitus (T1DM) is disease caused by the destruction of β pancreatic cells. The activation T-lymphocyte and proliferation inhibitor are induced protein tyrosine phosphatase non-receptor type 22 (PTPN22). However, link between PTPN22 C1858T gene polymorphism T1DM still controversy. This study aimed to analyse in Indonesian children with T1DM.This case-control was conducted from March 2021 May 2022 Endocrinology Outpatient Clinic at Dr. Soetomo Hospital Tropical Disease Center...
Background: Type 1 diabetes mellitus (T1DM) is the most common chronic disease in children, with several severe short and long-term complications. Glycemic control an important aspect of management influential factor being compliance self-monitoring blood glucose (SMBG). Mostly, Indonesia, finger stick devices as a monitoring tool were frequently used. About 20% children follow recommendation to measure four six times daily. Methods: This single center, cross-sectional study that was...
Type 1 diabetes (T1D) is an organ-specific autoimmune disease related to the response against pancreatic β-cells. Zinc transporter 8 (ZnT8), islet-specific gene product localized β-cell insulin granule, was recently identified as autoantigen in T1D.To evaluate use of ZnT8 autoantibody (ZnT8A) for diagnosing T1D.This case-control study conducted at Dr. Soetomo General Hospital, Surabaya, Indonesia, from March May 2019. Children younger than 18 years age with T1D based on International Society...
More than 40 genes influence the progression of type 1 diabetes mellitus (T1DM), including human leukocyte antigen (HLA) alleles. Different HLA genotype patterns result in diverse rates T1DM development. class II DR, DQ, and DP vary among different populations ethnicities. Data on polymorphism Indonesia are lacking. Therefore, this study was designed to evaluate gene HLA-DQA1 HLA-DQB1 Indonesian children with T1DM.
CTLA-4 gene polymorphism plays an important role in children with type 1 diabetes mellitus (T1DM). However, data on this subject vary among different races and ethnics.To analyze CT-60 A/G 1822 C/T T1DM compared to control.The using polymerase chain reaction-restriction fragment length 25 controls. The inclusion criteria were patients regularly controlled at the Pediatric Endocrine Outpatient Clinic of Dr. Soetomo Hospital, aged 4-18 years willing join study exclusion hospitalized pediatric...
Treatment with antiseizure medications (ASMs) for more than 6 months requires monitoring of side effects, one which is a decreased level serum vitamin D. This study aimed to compare the influence therapies versus multiple ASMs on 25-hydroxy D (25-OHD) levels among children epilepsy.Our cross-sectional comparative was conducted in Paediatric Neurology Clinic at Soetomo Academic Hospital. Epileptic aged 2-18 years who had been using least were enrolled and grouped according whether they taking...
Background Diabetic ketoacidosis (DKA) is a complication of type I diabetic mellitus (TIDM). Early recognition and prompt treatment can reduce mortality. Objective To evaluate the profiles patients with ketoasidosis in Dr. Soetomo Hospital, Surabaya, Indonesia. Methods Retrospective medical records admitted to pediatric intensive care unit DKA Indonesia from January 2002 June 2013 were reviewed. The data collected included clinical parameters, laboratory imaging results, predisposing...
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BackgroundDiabetic ketoacidosis (DKA) is a complication of type I diabetic mellitus (TIDM).Early recognition and prompt treatment can reduce mortality.Objective To evaluate the profiles patients with ketoasidosis in Dr. Soetomo Hospital, Surabaya, Indonesia.Methods Retrospective medical records admitted to pediatric intensive care unit DKA Indonesia from January 2002 June 2013 were reviewed.The data collected included clinical parameters, laboratory imaging results, predisposing factors,...
Thyroid dysfunction is the most common endocrine disorder in Down syndrome (DS) children. Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) one of immune regulatory genes that correlates with Hashimoto's thyroiditis (HT). However, studies on CTLA-4 +49A/G DS children HT are still limited. We aimed to evaluate gene polymorphism HT. This case-control study, conducted from February 2020 2022 at Dr. Soetomo General Hospital, Surabaya, enrolled 40 and 50 healthy The DNA sequencing was...
Background: Type 1 Diabetes Mellitus (T1DM) is a chronic disease that requires complicated therapies. The coronavirus 2019 (COVID-19) pandemic has caused lockdown restrictions, compromising access to medical care, including T1DM management. Poor medication adherence may affect the quality of life (QoL) and glycemic control. Objectives: This study analyzed association among QoL, adherence, control in patients during COVID-19 pandemic. Methods: recruited aged 5 - 18 who regularly visited...
Children with Down syndrome (DS) are prone to developing autoimmune thyroid disease (AITD). Previous studies found lower selenium (Se) levels in children AITD. Glutathione peroxidase-3 (GPx3) and selenoprotein-P (SePP) widely used measure Se levels. DS tend have levels, the main contributor hypothyroidism this population. This study aimed analyze Se's role AITD Indonesian DS.This cross-sectional was conducted between February 2021-June 2022 at Pediatric Outpatient Clinic of Dr Soetomo...
Background Transfusion-dependent thalassemia (TDT) has a major impact on child’s growth and is associated with stunting, risk of vitamin D deficiency, decreased insulin-like factor-1 (IGF-1). To date, the relationship between levels stunting in TDT remains unclear. Futhermore, role IGF-1 mediating patients still unknown. 
 Objective investigate as well children TDT.
 Methods This cross-sectional study involved 50 aged 5 to 18 years, included consecutively from Pediatric...
McCune-Albright syndrome (MAS) is a rare genetic disease characterized by skeletal, cutaneous, and endocrine system involvement. We report 6-year-old girl with fibrous dysplasia, café-au-lait macula, multiple hyperfunctional endocrinopathies. Treatment was palliative, the patient planned for surgery on bilateral femur fractures rehabilitation program.
The use of technology has rapidly increased in the past century. Artificial intelligence (AI) and information (IT) are now applied healthcare medical education. purpose this study was to assess readiness Indonesian teaching staff pediatric residents for AI integration into curriculum.
Background: Sleep is essential for growth, development, and health, with inadequate sleep linked to risks such as obesity, hypertension, mood disorders. patterns differ by sex, females often experiencing poorer quality greater susceptibility disturbances due factors like the menstrual cycle. Adolescents, particularly boarding students, face unique challenges from academic extracurricular demands, potentially impacting growth. This study aimed at studying relationship between height within...
Purpose: This study aims to examine the relationship between early puberty onset and childhood dietary patterns in Indonesian adolescents, as well effects of nutritional factors including obesity, on pubertal disorders. Approach, methodology, design: Eighty-five sixth-graders participated a non-randomized intervention trial at Elementary School Muhammadiyah 16 Surabaya. Pediatricians conducted seminars that provided participants with information regarding puberty. The data was analyzed using...
Introduction: Healthy diet is essential for healthy development as well growth. The focus of nutritional evaluation in children to recognize and avoid conditions such malnutrition obesity, addition the associated rise mortality morbidity. This study aims describe dietary intake nutrition status junior high school students. Methods: cross-sectional was conducted from Mei – August 2024 involved aged 12-15 years old at private school. General information collected by questionnaire....