- Pediatric Hepatobiliary Diseases and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Child Nutrition and Feeding Issues
- Child Nutrition and Water Access
- Liver physiology and pathology
- Infant Health and Development
- Public Health and Nutrition
- Gastrointestinal motility and disorders
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Mesenchymal stem cell research
- Vitamin K Research Studies
- Diet and metabolism studies
- Esophageal and GI Pathology
- Congenital gastrointestinal and neural anomalies
- Vaccine Coverage and Hesitancy
- Epilepsy research and treatment
- COVID-19 Impact on Reproduction
- Congenital Diaphragmatic Hernia Studies
- Liver Diseases and Immunity
- Methodologies in Health Research and Practice
University of Indonesia
2009-2024
Kyushu University
2011-2024
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2009-2024
Vrije Universiteit Brussel
2023
Indonesian Pediatric Society
2022
Institute of Child Health
2021
Kaiser Permanente
2011
To determine the natural history of infant regurgitation during first year life.Parents recorded prospectively frequency for 1 week before consultation life. A sub-group analysis according to method feeding was planned.A total 130 infants an original sample 163 (80%) newborns were followed up year. Daily spilling highest month life (73%) and decreased gradually 50% fifth During 2 months life, 20% regurgitated more than four times per day. After age 12 months, only 4% had daily...
Abstract Introduction Liver transplantation is a gold standard treatment for intractable liver diseases. Because of the shortage donor organs, alternative therapies have been required. Due to their potential differentiate into variety mature cells, stem cells are considered feasible cell sources regeneration. Stem from human exfoliated deciduous teeth (SHED) exhibit hepatogenic capability in vitro . In this study, we investigated vivo capabilities homing and hepatocyte differentiation...
We aimed to study the epidemiology and risk factors, including exposure emotional stress, for constipation in Indonesian children adolescents of 10–17 year age group. A cross-sectional survey using a validated, self-administered questionnaire was conducted randomly selected nine state junior high schools from five districts Jakarta. All them were urban areas. Constipation defined as diagnosis by Rome III criteria. Of 1796 included analysis, 328 (18.3%; 95% CI 016–0.2) had constipation....
While the number of cases multisystem inflammatory syndrome in children (MIS-C) is increasing, reported Asian countries are still low, particularly Indonesia. This study aimed to describe characteristics patients with MIS-C a tertiary referral hospital Indonesia.This cross-sectional collected data admitted Dr. Cipto Mangunkusumo from March 2020 April 2021.The first case was detected 5 months after coronavirus disease 2019 Thirteen out 158 positive for COVID-19 were diagnosed during period....
Abstract Background and Aim Even with advancement of medical technologies, liver transplantation still faces several major challenges. Hence, other treatment modalities are urgently needed for patients end‐stage disease. Stem cells from human exfoliated deciduous teeth (SHED) was discovered to have highly proliferative pluripotent properties; including differentiation into hepatocyte‐like cells. This study aims investigate the capability intrasplenic transplanted SHED SHED‐Hep in inducing...
To outline the preliminary development and validation of a questionnaire for diagnosing epilepsy distinguishing focal generalized among infants children in Indonesia, where electroencephalography pediatric neurologists are generally not available.
Purpose: Peroxisome proliferator-activated receptor gamma (PPAR-γ) has a key role in hepatic fibrogenesis by virtue of its effect on the stellate cells (HSCs).Although many studies have shown that PPAR-γ agonists inhibit liver fibrosis, mechanism remains largely unclear, especially regarding cross-talk between and other potent fibrogenic factors.Methods: This experimental study involved 25 male Wistar rats.Twenty rats were subjected to bile duct ligation (BDL) induce further divided into an...
Although domperidone is used frequently to treat infant regurgitation, efficacy data are scarce. Cisapride was previously in the same indication.Domperidone and cisapride were compared an investigator-blinded, prospective comparative trial by evaluating (a) frequency of (b) acid reflux (c) cardiac side effects infants regurgitating >4 times/day since >2 weeks with reflux-associated symptoms discomfort, after conservative treatment failure.Within first week, regurgitation decreased both...
Abstract Background Functional abdominal pain disorders (FAPD) have been widely reported as a major group of gastrointestinal across the world. This study describes prevalence, related factors, symptomatology and its relationship to emotional stress in Indonesian adolescents. Methods is cross-sectional study. Adolescents aged 10 17 years from nine randomly selected state schools five districts Jakarta, Indonesia, were invited participate. A translated validated Rome-III...
The prophylactic oral administration of vitamin K to newborns has markedly reduced the incidence deficiency (VKD); however, intracranial hemorrhage (ICH) is still one complications found in biliary atresia (BA) patients and associated with VKD bleeding. Therefore, we aimed investigate long-term outcome ICH BA who previously received during neonatal period.Eighty-eight consecutive infants were treated followed up at Kyushu University Hospital from 1979 2009. clinical records imaging study...
Duodenal atresia (DA) is a well-known neonatal intestinal disease. Even after surgery, the proximal segment can continue to be severely dilated with hypoperistalsis, resulting in dysmotility problems later life. No data have been published regarding morphologic differences between and distal regions of obstructed sites intramural components DA.Operative duodenal samples (N = 12) from cases DA (age 1-3 days) were used. Age-matched controls 2) All specimens immunohistochemically stained...
All sectors are affected due to COVID-19 pandemic occurring worldwide, including the education industry. School closure had been taking place for more than a year in Indonesia. Despite controversies, Indonesian government decided begin school reopening.This study aims assess parental readiness reopening, and factors affecting attitude toward reopening.A cross-sectional using online questionnaire distributed via official Pediatric Society (IPS) social media account collected between March...
Background Irritable bowel syndrome (IBS) is a commonfunctional gastrointestinal disorder. Increasing prevalences havebeen reported in Asian adolescent populations, however, therehave been few reports on Indonesian adolescents.Objective To investigate the prevalence of IBS and associatedfactors among adolescents Jakarta.Methods This cross-sectional study included senior high schoolstudents district Jakarta. Students were asked to fillquestionnaires based Rome III criteria for IBS. They...
Hypoganglionosis resembles Hirschsprung's disease as in both diseases, patients may present with severe constipation or pseudo-obstruction. To date, diagnosis of hypoganglionosis is still difficult to be established due lack international consensus regarding diagnostic criteria. This study aims evaluate the use immunohistochemistry provide objective support for our initial subjective impression well describe morphological features this study.This a cross-sectional study. Three resected...
Latar belakang. Infeksi nosokomial (IN) pada bayi baru lahir sampai saat ini masih merupakan masalahserius di setiap rumah sakit karena dapat meningkatkan morbiditas, mortalitas, lama dan biaya rumahsakit serta risiko kecacatan yang terinfeksi.Tujuan penelitian. Mengetahui gambaran epidemiologi, pola kuman resistensi mikroorganisme penyebabIN aliran darah (INAD) ruang rawat Divisi Perinatologi Departemen IKA RSCM.Metode. Penelitian penelitian prospektif deskriptif dengan desain studi seksi...
Background: Neonatal gastrointestinal emergencies refer to a set of life-threatening conditions affecting the digestive system newborn within first 28 days life and often associated with high morbidity mortality. As such, these require immediate accurate diagnosis as well proper treatment optimize outcomes patients. This condition has potential obstruct flow gastric content leading vomiting, failure thrive, electrolyte imbalances. Discussion: Gastrointestinal obstruction is one most common...