A5043545534- Sepsis Diagnosis and Treatment
- Neonatal and Maternal Infections
- Bacterial Identification and Susceptibility Testing
- SARS-CoV-2 and COVID-19 Research
- Hemodynamic Monitoring and Therapy
- Public Health and Nutrition
- Renal function and acid-base balance
- Acute Kidney Injury Research
- Antimicrobial Resistance in Staphylococcus
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Non-Invasive Vital Sign Monitoring
- Cardiac Arrest and Resuscitation
- Blood Pressure and Hypertension Studies
- Pneumonia and Respiratory Infections
- Muscle and Compartmental Disorders
- Kawasaki Disease and Coronary Complications
- Hepatitis B Virus Studies
- Gut microbiota and health
- Neonatal Respiratory Health Research
- Clinical Nutrition and Gastroenterology
- Heart rate and cardiovascular health
- Child Nutrition and Water Access
- Animal Virus Infections Studies
- Heart Rate Variability and Autonomic Control
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2013-2024
University of Indonesia
2014-2024
BackgroundThe incidence of coronavirus disease 2019 (COVID-19) is still increasing rapidly, but little known about the prevalence and characteristics fatal cases in children Indonesia. This study aimed to describe with COVID-19 outcomes a tertiary referral hospital Indonesia.MethodsThis cross-sectional used data collected from medical records patients admitted Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia March October 2020.ResultsDuring period, 490 were diagnosed suspected probable...
BACKGROUND According to the WHO Target Product Profiles for COVID-19 Vaccines, vaccine development should be indicated active immunization in all populations, conjunction with other control measures curtail pandemic. Several RBD-based vaccines are being evaluated and have shown advantages. CoV2-Bio was developed based on wild-type SARS-CoV-2 RBD amino acid sequence, representing residues of spike protein Wuhan-Hu-1 isolate. This study aimed evaluate safety immunogenicity when compared...
Abstract Background High-flow nasal cannula (HFNC) is often used in pediatric populations with respiratory distress. In adults, the respiratory-rate oxygenation (ROX) index as a predictor of HFNC therapy; however, children have age-associated differences rate, thus may not be applicable to children. This study aims find reliability ROX and modified P-ROX predictors therapy failure patients. Methods Subjects this analytical cross-sectional were taken from January 2023 until November Cipto...
While the number of cases multisystem inflammatory syndrome in children (MIS-C) is increasing, reported Asian countries are still low, particularly Indonesia. This study aimed to describe characteristics patients with MIS-C a tertiary referral hospital Indonesia.This cross-sectional collected data admitted Dr. Cipto Mangunkusumo from March 2020 April 2021.The first case was detected 5 months after coronavirus disease 2019 Thirteen out 158 positive for COVID-19 were diagnosed during period....
Latar belakang: prevalensi anemia defisiensi besi masih tinggi terutama pada bayi. Deteksidini terhadap bayi dengan risiko sangat diperlukanuntuk mencapai tumbuh kembang optimal.Tujuan: untuk mengetahui besi.Bahan dan cara metode: studi deskriptif belah lintang dilakukan di empat Puskesmasdi Jakarta Timur. Populasi sampel adalah umur 4-12 bulan yang tinggal wilayahKecamatan Matraman sekitarnya Maret 2004. Sampling diambil denganmetode convenient, pengumpulan data pengisian kuesioner oleh ibu...
Abstract Introduction The PedHAL questionnaire is employed in measuring the activities of haemophilia children. PedHALshort was developed 2022 to determine most relevant item for assessment. Haemo‐QoL assesses quality life Aim Determine validity and reliability Indonesia language version compared Indonesian population. Methods A cross‐sectional study conducted Jakarta, Indonesia. subjects were children (4‐16 years old) with moderate or severe B repeated joint bleeding. daily activity...
Background Sepsis is a leading cause of pediatric morbidity and mortality. The prevalence sepsis mortality in Indonesia varies between 22.5 to 52%.
 Objective To identify the clinical criteria for predicting evaluate performance PELOD-2 score.
 Methods This retrospective cohort study included patients admitted emergency department or intensive care unit (PICU) Cipto Mangunkusumo Hospital, Jakarta, Indonesia, from January 2015 May 2020. Demographic characteristics (age sex),...
Latar belakang.Masalah infeksi yang sering ditemui di ICU anak, disebabkan berbagai pemakaian antibiotik. Peningkatan penggunaan antibiotik diikuti dengan risiko penurunan kepekaannya sehingga perlu pengendalian pemakaiannya.Tujuan.Evaluasi secara kualitatif Pediatric Intensive Care Unit(PICU) menggunakan alur Gyssens.Metode.Uji potong lintang retrospektif mengevaluasi melalui kartu monitoring serta dilakukan analisis Gyssens PICU dari tanggal 10 Februari 2012 sampai 31 Juli...
Latar belakang. Anak yang dirawat di PICU (pediatric intensive care unit) cenderung untuk mengalamimalnutrisi sejak masuk atau selama perawatan. Hal ini akan memperberat penyakit dasar dan komplikasinya,memperpanjang lama rawat, serta meningkatkan mortalitas. Perhitungan kebutuhan kalori tepat sertapemberian nutrisi adekuat sesuai merupakan target perawatan anak PICU. Baik underfeedingataupun overfeeding dapat terjadi perawatan.Tujuan. Mengetahui status gizi awal pasien Anak, pola pemberian...
The WHO declared the COVID-19 pandemic on March 11, 2020, then several centres developed Covid-19 vaccines. Indovac vaccine contains SARS-CoV-2 RBD antigen adjuvanted with Alum and CpG1018. This article reported Jakarta Centre Phase 1 trial results of safety immunogenicity in Kota Depok. study is a randomised, observer-blinded, active-control (Sinovac) clinical trial. included 175 healthy adults aged 18–70 75 participants were enrolled by centre. Two doses given 28 days apart. Four formulas...
Latar belakang. Penilaian kesadaran penting dilakukan pada pasien anak dengan sakit kritis untuk memperkirakanprognosis. Modifikasi Glasgow Coma Scale (GCS) banyak digunakan menilai tetapi memilikiketerbatasan terutama yang diintubasi. Terdapat skor alternatif baru yaitu Full Outline ofUnResponsiveness score (FOUR score) dapat terintubasi.Tujuan. Membandingkan FOUR GCS dalam menentukan prognosis kritis, sehinggapemeriksaan sebagai pengganti GCS.Metode. Penelitian prospektif observasional...
Background The mortality rate for children with septic shock is stil quite high in low-income and middle-income countries (31.7%). One of the most widely used scoring systems to assess sepsis or Paediatric Logistic Organ Dysfunction 2 (PELOD-2). However, it requires various laboratory evaluations. A non-invasive, fast easy method needed at an early stage. Therefore, this study aims evaluate ability Vascular Reactivity Index (VRI) compared PELOD-2 score as a predictor based on vascular...
Fluid creep, used as a drug diluent can contribute to fluid and electrolyte balance. creep brings substantial volume load patients, especially in critically ill children. This study is conducted evaluate the correlation of with balance cross-sectional was single tertiary center. We include children aged 1 month- 18 years pediatric intensive care unit (PICU). Exclusion criteria were patients receiving renal replacement therapy plasmapheresis. Fluids intake recorded at admission first 24 hours...
<title>Abstract</title> Background High-flow nasal cannula (HFNC) is often used in pediatric populations with respiratory distress. In adults, the respiratory-rate oxygenation (ROX) index as a predictor of HFNC therapy; however, children have age-associated differences rate, thus may not be applicable to children. This study aims find reliability ROX and modified P-ROX predictors therapy failure patients. Methods Subjects this analytical cross-sectional were taken from January 2023 until...
Background: COVID-19 is one of the most devastating pandemics 21st century. Vaccination effective prevention methods in combating COVID-19, and type vaccine being developed was protein subunit recombinant vaccine. We evaluated efficacy CoV2-IB 0322 Depok, Indonesia. Methods: This study aimed to assess humoral cellular immune response compared an active control (COVOVAX™ Vaccine). A total 120 subjects were enrolled randomized into two groups, with 60 each group. Participants received either...
<title>Abstract</title> Background Acute kidney injury (AKI) is a commonly found complication in critically ill children. One of the key treatments these children continuous replacement therapy (CKRT), especially those who are hemodynamically unstable. However, due to its costly and complex procedure, there has been some challenges implementing this treatment developing countries. Therefore, aim study present comprehensive analysis clinical profiles our pediatric patients during 9-year CKRT...
Background The 2015 Surviving Sepsis Campaign (SSC) guidelines for management of shock recommend blood lactate to assess the success resuscitation in shock. However, a study adults found that 1/3 septic patients had normal levels (alactatemia) and lower mortality rates.Objective To evaluate profiles, possible factors affecting levels, outcomes pediatric emergency room (ER) intensive care unit (PICU).Methods This was retrospective on aged 1 month 18 years ER or PICU from June 2014 December...
Latar belakang. Stroke volume variation (SVV) adalah parameter hemodinamik untuk menilai fluid responsiveness. Pengukuran SVV dapat dilakukan dengan USCOM yang merupakan alat pemantauan non invasif berbasis ekokardiografi Doppler.Tujuan. Mengetahui nilai cut-off point (titik potong optimal) sebagai prediktor responsiveness pada pasien ventilasi mekanik.Metode. Penelitan dilaksanakan di Pediatric Intensive Care Unit (PICU) dan Gawat Darurat (UGD) Rumah Sakit Cipto Mangunkusumo (RSCM),...
Background Acute diarrhea is a common health problem in Indonesia. During acute diarrhea, changes gut microbiota are marked by decrease beneficial microbes Bifidobacterium and Lactobacillus, increased pathogenic bacteria Enterobacter Clostridium. Such microbial imbalances known as dysbiosis. Treatment with probiotics may help repair dysbiosis, quicken healing time, complications.
 Objective To assess for dysbiosis during determine if it can be normalized probiotic treatment.
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Backgi-ound Incidence of acute kidney injury (AKI) in critically illchildren and its mortality rate is high. The lack a uniform definitionfor AKI leads to failure determining injury, delayedtreatment, the inability generalize research results.Objectives To evaluate pediatric RIFLE (pRIFLE) criteria (riskfor renal dysfunction, kidney, function,loss function, end-stage disease) for diagnosingand following clinical course ill children. Wealso aimed compare severity on days 1 3...
Aims & Objectives: Pediatric Intensive Care unit (PICU) Cipto Mangunkusumo Hospital (CMH) is the national referral and government tertiary center for intensive care in Indonesia. Therefore, it important to identify patient profiles outcomes PICU CMH serve better quality performance. This study describe characteristics last one-year period. Methods a retrospective study. Data was collected from medical record January-October 2017. identified surgical vs indication, bed occupancy rate (BOR),...
Background Acute diarrhea is a common health problem in Indonesia. During acute diarrhea, changes gut microbiota are marked by decrease beneficial microbes Bifidobacterium and Lactobacillus, increased pathogenic bacteria Enterobacter Clostridium. Such microbial imbalances known as dysbiosis. Treatment with probiotics may help repair dysbiosis, quicken healing time, complications.
 Objective To assess for dysbiosis during determine if it can be normalized probiotic treatment.
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