A5052951959- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- HIV/AIDS Research and Interventions
- Diverse Scientific Research Studies
- COVID-19 Pandemic Impacts
- Diabetes and associated disorders
- COVID-19 and Mental Health
- COVID-19 Prevention and Impact
- Vitamin C and Antioxidants Research
- COVID-19 Impact on Reproduction
- Animal Virus Infections Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Delphi Technique in Research
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- HIV-related health complications and treatments
- vaccines and immunoinformatics approaches
- Hemophilia Treatment and Research
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Hepatitis C virus research
- Influenza Virus Research Studies
- Hepatitis B Virus Studies
University of Indonesia
2020-2025
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2020-2025
Pandemi Coronavirus disease 2019 (COVID-19) telah berlangsung sejak Maret 2020 hingga saat ini sudah hampir dua tahun melanda dunia, tak terkecuali Indonesia. Dalam perjalanannya sebagai patogen, SARS-CoV-2 mengalami beberapa mutasi menjadi berbagai varian yang perhatian dunia. Varian-varian virus dikhawatirkan menghambat resolusi wabah, bahkan membuat wabah tidak terkendali. Masih banyak kontroversi dan riset berjalan tentang varian-varian baru SARS-CoV-2. Mekanisme penularan cepat belum...
BACKGROUND According to the WHO Target Product Profiles for COVID-19 Vaccines, vaccine development should be indicated active immunization in all populations, conjunction with other control measures curtail pandemic. Several RBD-based vaccines are being evaluated and have shown advantages. CoV2-Bio was developed based on wild-type SARS-CoV-2 RBD amino acid sequence, representing residues of spike protein Wuhan-Hu-1 isolate. This study aimed evaluate safety immunogenicity when compared...
Cognitive impairment among patients with systemic lupus erythematosus (SLE) can significantly impact quality of life (QoL). This study aimed to determine the prevalence cognitive in SLE using Montreal Assessment Indonesian version (MoCA-INA) and assess its association QoL. was a cross-sectional from outpatient clinic at Cipto Mangunkusumo Hospital, Jakarta. Data collected included patient characteristics, MoCA-INA scores, LupusQoL questionnaire, Hospital Anxiety Depression Scale (HADS)...
Background: Health care workers (HCWs) are a high-priority group for COVID-19 vaccination several reasons. behavior theory-based studies on the intention or acceptability of among Indonesian HCWs is lacking. Using an integrated behavioral model, this research sought to identify health workers’ intentions obtain vaccines. Methods: A countrywide cross-sectional questionnaire-based survey was conducted. The questionnaire constructed basis IBM (integrated model) constructs and scored seven-point...
In Indonesia, COVID-19 vaccination hesitancy persists among health care workers (HCWs). Understanding the motives and challenges impacting HCWs’ acceptance of booster is critical. Efforts are still needed to overcome apprehension about taking a dosage. This study aims analyze vaccine HCWs in Jakarta using an extended, modified model behavior theories, namely The Health Belief Model (HBM) Theory Planned Behavior (TPB). A cross-sectional survey from November 2021 January 2022 was distributed...
This study aimed to analyze the knowledge, attitude, and behavior of people living with HIV (PLWH) during COVID-19 pandemic pandemic's impact on their socioeconomic conditions, antiretroviral adherence, worries.This cross-sectional was conducted in May-August 2020 at Integrated Center Dr. Cipto Mangunkusumo General Hospital, Indonesia. The data were collected using an online questionnaire offline paper-based questionnaire.A total 545 subjects participated this study, 72.8% (397) which male....
Patients with an autoimmune disease could be at higher risk of a poor outcome when contracting COVID-19 infection due to aberrant immune responses and use immunosuppressant therapies for chronic treatment. Here, we conducted retrospective study identify the factors related severity, hospitalization, mortality among patients diseases. We found 165 cases pre-existing diseases who had contracted between March 2020 September 2022. Data on demographical characteristics; diagnosis treatment;...
BackgroundHigh COVID-19 vaccine coverage is essential. Patients who are considered high risk for hypersensitivity reactions and have had an allergic reaction to the usually referred allergist assessment of vaccination. Administration a graded challenge (also known as provocation test) option that can be in this population. This primary objective study describe outcome test understand predicting factors associated with after secondary objective.MethodsAdult patients history first...
Background: COVID-19 is one of the most devastating pandemics 21st century. Vaccination effective prevention methods in combating COVID-19, and type vaccine being developed was protein subunit recombinant vaccine. We evaluated efficacy CoV2-IB 0322 Depok, Indonesia. Methods: This study aimed to assess humoral cellular immune response compared an active control (COVOVAX™ Vaccine). A total 120 subjects were enrolled randomized into two groups, with 60 each group. Participants received either...
Background/objectives: As people with human immunodeficiency virus experience longer life expectancy, other causes of morbidity and mortality are being increasingly identified. The incidence non-alcoholic fatty liver disease has recently been on the rise in Indonesia. People antiretroviral therapy also at an increased risk having disease. study aimed to define prevalence factors associated stable therapy. Methods: A cross-sectional virus, therapy, age younger than 18 years old, without...
Vaccine hesitancy can be a challenge for those with autoimmune diseases. This study investigated the acceptance of COVID-19 vaccination by patients diseases in Indonesia using integrated behavioral model (IBM). cross-sectional was conducted from December 2021 to February 2022. A total 404 completed survey. The majority respondents (57.9%) said they intended get vaccinated against COVID-19. IBM added demographic variables explained 54.1% variance intention (R2 = 0.541). Self-efficacy,...
Abstract Background According to WHO Target Product Profile for COVID-19 Vaccines, vaccine development should be indicated active immunization in all populations, including the elderly, conjunction with other control measures curtail or end an outbreak. In this study, we evaluated safety of SARS-CoV-2 protein subunit recombinant (CoV2-Bio) healthy population aged 18 years and above Indonesia. Methods This study is observer-blinded, randomized, controlled prospective phase 1 intervention...
There is no guideline concerning choice of antiretroviral therapy (ART) for HIV-infected patients after unplanned interruption. We conducted a retrospective cohort study reintroduced to first-line ART having interruption at least 1 month. Viral load was evaluated 6 18 months the reintroduction. were 100 included in our study, and 55 them achieved virological success. History single (adjusted odds ratio [aOR] 5.51%, 95% confidence interval [CI] 1.82-16.68, P = .003) CD4 count ≥200 cell/mm 3...
In sepsis, there is an increase in oxidative stress which plays important role further physiological derangement. Due to its potent antioxidant effect, vitamin C has been proposed as a potential adjunct treatment patients with sepsis. This study aims evaluate the benefits of administration A systematic search was conducted using electronic databases PubMed, Scopus, ProQuest, and Cochrane keywords combination C/ascorbic acid sepsis/septic. The limits included English language, human subjects,...