A5013746678- HIV-related health complications and treatments
- SARS-CoV-2 and COVID-19 Research
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Systemic Lupus Erythematosus Research
- Vaccine Coverage and Hesitancy
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- HIV Research and Treatment
- Diverse Scientific Research Studies
- Drug-Induced Adverse Reactions
- Animal Virus Infections Studies
- Gut microbiota and health
- COVID-19 Prevention and Impact
- COVID-19 Impact on Reproduction
- Pharmacological Effects of Natural Compounds
- Healthcare Quality and Satisfaction
- Public Health and Nutrition
- Clostridium difficile and Clostridium perfringens research
- Diabetes and associated disorders
- Diet and metabolism studies
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 Pandemic Impacts
Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2016-2025
University of Indonesia
2016-2025
Universitas Prima Indonesia
2020
Pada awal 2020, dunia dikejutkan dengan mewabahnya pneumonia baru yang bermula dari Wuhan, Provinsi Hubei kemudian menyebar cepat ke lebih 190 negara dan teritori. Wabah ini diberi nama coronavirus disease 2019 (COVID-19) disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2). Penyebaran penyakit telah memberikan dampak luas secara sosial ekonomi. Masih banyak kontroversi seputar ini, termasuk dalam aspek penegakkan diagnosis, tata laksana, hingga pencegahan. Oleh...
Gut dysbiosis has a role in the pathogenesis of lupus. Synbiotic supplementation may restore balance gut microbiota. This study investigated whether synbiotics could improve microbiota and systemic inflammation lupus patients. randomized, double-blind, placebo-controlled trial was conducted adult erythematosus (SLE) Subjects were randomized to receive either or placebo. Fecal microbiota, hs-CRP, IL-6, IL-17 measured at baseline after 60 days. Patients who fulfilled inclusion criteria into...
Cognitive impairment among patients with systemic lupus erythematosus (SLE) can significantly impact quality of life (QoL). This study aimed to determine the prevalence cognitive in SLE using Montreal Assessment Indonesian version (MoCA-INA) and assess its association QoL. was a cross-sectional from outpatient clinic at Cipto Mangunkusumo Hospital, Jakarta. Data collected included patient characteristics, MoCA-INA scores, LupusQoL questionnaire, Hospital Anxiety Depression Scale (HADS)...
Background: Health care workers (HCWs) are a high-priority group for COVID-19 vaccination several reasons. behavior theory-based studies on the intention or acceptability of among Indonesian HCWs is lacking. Using an integrated behavioral model, this research sought to identify health workers’ intentions obtain vaccines. Methods: A countrywide cross-sectional questionnaire-based survey was conducted. The questionnaire constructed basis IBM (integrated model) constructs and scored seven-point...
The COVID-19 pandemic has caused significant morbidity and mortality worldwide, especially among health-care workers. One of the most important preventive measures is vaccination. This study examined factors associated with incidence rate SARS-CoV-2 infection after mRNA-1273 booster vaccination (preceded by CoronaVac primary vaccination) antibody profile workers at one tertiary hospitals in Indonesia. was a combined retrospective cohort cross-sectional study. Three hundred who were given...
Background: The transition to dolutegravir-containing antiretroviral therapy (ART) in low- and middle-income countries (LMICs) was complicated by an initial safety signal May 2018 suggesting that exposure dolutegravir at conception possibly associated with infant neural tube defects. On the basis of additional evidence, July 2019, World Health Organization recommended for all adults adolescents living HIV. Objective: To describe uptake disparities sex age group LMICs. Design: Observational...
Cotrimoxazole (CTX) is recommended as prophylaxis against Pneumocystis jiroveci pneumonia, malaria and other serious bacterial infections in HIV-infected patients. Despite its vitro activity Mycobacterium tuberculosis, the effects of CTX preventive therapy on tuberculosis (TB) remain unclear. Adults living with HIV enrolled a regional observational cohort Asia who had initiated combination antiretroviral (cART) were included analysis. Factors associated new TB diagnoses after entry survival...
Objective Needlestick and sharps injuries among healthcare workers (HCWs) pose significant occupational health problems. We aim to provide incidence other epidemiological aspects of needlestick sharp (NSSIs) HCWs in a tertiary teaching hospital Indonesia, inform the evaluation NSSIs prevention programme. Methods A cohort study was conducted at Cipto Mangunkusumo Hospital Jakarta. analysed data injury programme between January 2014 December 2017. Incidence calculated per 1000 person-years...
After successful of antiretroviral therapy, highly effective direct acting antiviral (DAA) make HCV elimination reasonable in HIV/HCV co-infected patients. However, achieving this target, there are still barriers to start DAA treatment, particularly the area liver fibrosis assessment that determine duration therapy. We aimed assess diagnostic performance APRI and FIB-4 for diagnosing cirrhosis patients using hepatic transient elastography (TE) as gold standard.This is a retrospective study...
Facing the rising cases of with higher fatalities COVID-19, some countries decided to give third dose vaccine as a booster. As 9 January 2022, 90.31% health workers in Indonesia have received vaccine. This study aims provide an evaluation adverse events following immunization (AEFI) single center form basis for ensuring safety booster administration nationally. A retrospective, cross-sectional was conducted using online survey. Demographic data, AEFI complaints, and factors influencing AEFIs...
In Indonesia, COVID-19 vaccination hesitancy persists among health care workers (HCWs). Understanding the motives and challenges impacting HCWs’ acceptance of booster is critical. Efforts are still needed to overcome apprehension about taking a dosage. This study aims analyze vaccine HCWs in Jakarta using an extended, modified model behavior theories, namely The Health Belief Model (HBM) Theory Planned Behavior (TPB). A cross-sectional survey from November 2021 January 2022 was distributed...
Background Inflammatory conditions and oxidative stress increase in HIV infection, inflammation increases the risk of cardiovascular disease. Ramadan fasting is known to reduce diabetic patients. This study examined effects on high-sensitivity C-reactive protein (hs-CRP) levels total antioxidant status (TAOS) patients antiretroviral therapy (ART). Methods was a prospective cohort comparing HIV-infected stable ART who fasted throughout did not fast during Ramadan. Inclusion criteria were men...
Abstract Background Anxiety and depression are psychosomatic disorders that frequently observed in chronic conditions such as systemic lupus erythematosus (SLE). can be induced by immunological neurotransmitter dysregulation, which is characterized hypothalamic–pituitary–adrenal (HPA) axis dysfunction, production of proinflammatory cytokines, activation complement the blood, C3 C4. The causes anxiety SLE complex, ranging from neuropsychiatric involvement to drug adverse effects. Detecting...
This study aimed to analyze the knowledge, attitude, and behavior of people living with HIV (PLWH) during COVID-19 pandemic pandemic's impact on their socioeconomic conditions, antiretroviral adherence, worries.This cross-sectional was conducted in May-August 2020 at Integrated Center Dr. Cipto Mangunkusumo General Hospital, Indonesia. The data were collected using an online questionnaire offline paper-based questionnaire.A total 545 subjects participated this study, 72.8% (397) which male....
Summary Data on markers of hepatitis C virus ( HCV ) disease in HIV ‐ ‐coinfected patients resource‐limited settings are scarce. We assessed RNA , genotype GT ), IL 28B and liver fibrosis (FibroScan ® 480 ‐infected with positive antibody four treatment centres South‐East Asia. enrolled 165 (34.4%) Jakarta, 158 (32.9%) Bangkok, 110 (22.9%) Hanoi 47 (9.8%) Kuala Lumpur. Overall, 426 (88.8%) were male, the median IQR age was 38.1 (34.7‐42.5) years, 365 (76.0%) reported exposure through...
The longevity of vaccine effectiveness and antibody titer after the Moderna mRNA COVID-19 vaccination booster in healthcare workers Indonesia is not known.We performed a prospective observational study at Universitas Hospital vaccination. An Immunology Analyzer with Chemiluminescence Immunoassay (CLIA) test was used to examine Anti SARS-CoV-2 S-RBD levels. Antibody levels were classified into two systems (3 categories, 2 categories).There 31 male subjects (75.6%), 33 (80.5%) aged 25-39...
Patients with an autoimmune disease could be at higher risk of a poor outcome when contracting COVID-19 infection due to aberrant immune responses and use immunosuppressant therapies for chronic treatment. Here, we conducted retrospective study identify the factors related severity, hospitalization, mortality among patients diseases. We found 165 cases pre-existing diseases who had contracted between March 2020 September 2022. Data on demographical characteristics; diagnosis treatment;...
Abstract Background People living with HIV (PLHIV) have higher risk of COVID-19 infection and mortality due to COVID-19. Health professionals should be able assess PLHIV who are more likely develop severe provide appropriate medical treatment. This study aimed clinical factors associated severity developed a scoring system predict among PLHIV. Methods retrospective cohort evaluated at four hospitals diagnosed during the first second wave pandemic in Indonesia. The independent related were...
BackgroundHigh COVID-19 vaccine coverage is essential. Patients who are considered high risk for hypersensitivity reactions and have had an allergic reaction to the usually referred allergist assessment of vaccination. Administration a graded challenge (also known as provocation test) option that can be in this population. This primary objective study describe outcome test understand predicting factors associated with after secondary objective.MethodsAdult patients history first...
Increasing numbers of people with HIV have received prolonged antiretroviral therapy (ART). We assessed long-term immunological and survival outcomes among from Asia (TAHOD) Australia (AHOD).