- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Malaria Research and Control
- COVID-19 epidemiological studies
- Vector-borne infectious diseases
- Cervical Cancer and HPV Research
- Viral Infections and Outbreaks Research
- Research on Leishmaniasis Studies
- Public Health and Environmental Issues
- COVID-19 Clinical Research Studies
- Leptospirosis research and findings
- Zoonotic diseases and public health
- Trypanosoma species research and implications
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Parasites and Host Interactions
- Platelet Disorders and Treatments
- Esophageal and GI Pathology
- HIV/AIDS Research and Interventions
- Preterm Birth and Chorioamnionitis
- Infectious Encephalopathies and Encephalitis
- Dengue and Mosquito Control Research
- Vaccine Coverage and Hesitancy
- Escherichia coli research studies
Universidad De Santander
2016-2025
Industrial University of Santander
2011-2023
Universidad de Santander
2017-2023
Instituto Nacional de Salud Pública
2012-2020
German Doctors
2020
Bielefeld University
2020
Brandeis University
2020
Pontificia Universidad Católica de Chile
2020
Universidad Anáhuac
2020
Google (United States)
2020
Community integration in dengue control requires assessments of knowledge, attitudes and practices (KAPs), which can vary widely according to demographic educational factors. We aimed describe compare the KAPs level education municipalities Caribbean region Colombia.A survey was administered from October December 2015, including families selected through probabilistic sampling eleven municipalities. The analysis focused on comparative description responses education. KAP prevalence ratios...
Background Dengue imposes a substantial economic and disease burden in most tropical subtropical countries. incidence severity have dramatically increased Mexico during the past decades. Having objective comparable estimates of dengue is essential to inform health policy, increase awareness, assess impact prevention control technologies. Methods Findings We estimated annual for years 2010–2011. merged multiple data sources, including prospective cohort study; patient interviews macro-costing...
We evaluated biochemical alterations as predictors of dengue hemorrhagic fever (DHF). Patients with confirmed infection virus were prospectively for the first seven days disease to determine their final clinical outcome. Serum samples taken 48-96 hours after onset used tests. Of 199 patients, 30 developed DHF. Cases DHF had higher levels lactate dehydrogenase (LDH), creatine kinase (CK), and aspartate aminotransferase, lower albumin, total cholesterol, triglycerides. Multivariate analysis...
Dengue is mostly considered an acute illness with three phases: febrile, critical possible hemorrhagic manifestations, and recovery. But some patients present persistent symptoms, including fatigue depression, as acknowledged by the World Health Organization. If symptoms affect a non-negligible share of patients, burden dengue will be underestimated. On basis systematic literature review econometric modeling, we found significant relationship between reporting persisting time. We updated...
Abstract Pseudomonas aeruginosa is a remarkably adaptive bacterium frequently implicated in severe, sometimes fatal infections within healthcare institutions. The origins of clinical strains have generated considerable debate, suggesting that infectious variants emerge through selection from broader environmental bacterial population. Our investigation explored the physiological differences between (indoor) and P. isolated hospital over year. We assessed various parameters, including...
Dengue is currently the most widespread vector-borne disease, and its transmission has been intensively studied in endemic/hyperendemic localities. However, to obtain a complete picture of dengue transmission, it necessary study nonendemic Imported cases have reported Mexico City, presence eggs vector Aedes aegypti detected. In present study, we determined prevalence IgG antibodies against virus four city boroughs via random cluster sampling individuals aged 5-35 years. The weighted...
Humoral immune response against dengue virus (DENV) is an important component in dengue-endemic transmission. We conducted a cross-sectional nested cohort study to determine the seroprevalence and frequency of neutralizing antibodies DENV serotypes two endemic localities state Morelos, Mexico. The participants ( N = 1,196) were screened previous exposure DENV. Overall was 76.6% (95% confidence interval [95% CI] 73.6–79.2), prevalence 5- 9-year-old group 82.5% CI 67.2–92.7), 45% 29.3–61.5),...
Resumen Para el control del dengue es esencial reconocimiento de los determinantes conocimientos, actitudes y prácticas (CAP), cuales podrían estar condicionados por las experiencias percepciones la población a riesgo. El propósito este artículo estimar asociación entre percepción riesgo experiencia con CAP sobre dengue, en una endémica Colombia. Estudio analítico corte transversal muestreo probabilístico, polietápico conglomerados. Como medidas se estimaron razones prevalencia ajustadas...
Introducción.La definición de caso dengue la Organización Mundial Salud (
Dengue is a growing public health problem in tropical and subtropical cities. It transmitted by mosquitoes, the main strategy for epidemic prevention control insecticide fumigation. Effective management is, however, proving elusive. People's day-to-day movement about city believed to be an important factor epidemiological dynamics. We use simple model examine fundamental roles of broad demographic spatial structures initiation, growth control. show that key factors are local dilution,...
Abstract Background Dengue is commonly considered an acute illness and follows three phases: febrile, critical in some cases recovery. However, a number of studies have described continuation dengue symptoms for weeks or months, extending the recovery phase. Here we evaluate this persistence during convalescence. Methods Our clinical cohort study included patients who sought medical services 48 to 144 h from onset fever at seven hospitals ambulatory centers Morelos, Mexico. Seventy-nine...
In Colombia, human leptospirosis (HL) is a disease that has had mandatory notification rule since 2007. Humans usually acquire the infection through water contaminated with animal urine comes into direct contact cutaneous lesions, eyes or mucous membranes.To analyze spatiotemporal variability in occurrence of HL cases Colombia between 2007 and 2016, its relation El Niño Southern Oscillation (ENSO) cycle consequent anomalies rainfall clusters.An ecological study cases, aggregated by...
Urinary tract infection (UTI) is the most frequent bacterial infection. Some uropathogenic Escherichia coli (UPEC) genes have been associated with disease severity and antibiotic resistance. The aim was to determine association of nine UPEC virulence UTI resistance strains collected from adults community-acquired UTI.A case-control study (1:3) (38 urosepsis/pyelonephritis 114 cystitis/urethritis) conducted. fimH, sfa/foc, cvaC, hlyA, iroN, fyuA, ireA, iutA, aer (the last five are siderophore...
Low concordance between early clinical suspicion of dengue and its serological confirmationBackground: Early detection could help to prevent complications.The usefulness criteria for diagnosis the disease must be ascertained.Aims: To assess correlation laboratory dengue, done during first consultation in emergency room.To estimate impact on initial medical treatment.Patients Methods: Patients older than 5 years with an acute febrile syndrome that consulted 72 hours disease, 2004, at room...
The study of endemic dengue transmission is essential for proposing alternatives to impact its burden. traditional paradigm establishes that starts around cases, but there are few studies determine the risk.To assess association between peridomestic infection and exposure a index case (IC), cohort was carried out in two Mexican communities. People cohabitating with IC or living within 50-meter radius (exposed cohort) subjects areas no ICs 200-meter (unexposed were included.Exposure...
Human leptospirosis is an infection that most often affects tropical countries. Since 2007, Colombia requires the notification of disease cases, enabling observation increase in cases recent years. The objectives this article were to analyze environmental and socioeconomic variables evaluate their relationship with human cases. This ecological study on aggregated by municipality reported between 2007 2016. Spatial aggregation assessment was made using Getis-Ord Gi method, negative binomial...
Introduction Mathematical models and field data suggest that human mobility is an important driver for Dengue virus transmission. Nonetheless little known on this matter due the lack of instruments precise quantification study design difficulties. Materials methods We carried out a cohort-nested, case-control with 126 individuals (42 cases, 42 intradomestic controls population controls) goal describing patterns recently virus-infected subjects, comparing them those non-infected subjects...
Cutaneous leishmaniasis (CL) is a vector-borne disease that widely distributed in most tropical regions. Colombia has experienced an important increase its incidence during the last decade. There are CL transmission foci Colombian departments of Santander and Norte de Santander.To identify environmental socio-economic variables associated with municipalities northeast between 2007 2016.This was ecological study cases aggregated by municipality. The reported period were analyzed negative...