Michael Villa

ORCID: 0000-0003-0181-3719
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About
Contact & Profiles
Research Areas
  • Hormonal Regulation and Hypertension
  • Thyroid Cancer Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Adrenal Hormones and Disorders
  • Pituitary Gland Disorders and Treatments
  • Adrenal and Paraganglionic Tumors
  • Diabetes Management and Research
  • Diabetes Treatment and Management
  • Diet and metabolism studies
  • Cancer, Hypoxia, and Metabolism
  • Parathyroid Disorders and Treatments
  • Metabolism, Diabetes, and Cancer
  • Sexual Differentiation and Disorders
  • Telemedicine and Telehealth Implementation
  • Pancreatic and Hepatic Oncology Research
  • Bone health and treatments
  • Diabetes and associated disorders
  • LGBTQ Health, Identity, and Policy
  • Myasthenia Gravis and Thymoma
  • Vasculitis and related conditions
  • Pancreatitis Pathology and Treatment
  • Electrolyte and hormonal disorders
  • Neuroendocrine Tumor Research Advances
  • Liver Disease Diagnosis and Treatment
  • Neurofibromatosis and Schwannoma Cases

St. Luke's Medical Center
2011-2025

University of Asia and the Pacific
2012

Community Cancer Center
2010

University of California, Irvine
2010

American Society of Echocardiography
2009

National University Hospital
2004-2005

Abstract Context While guidelines have been formulated for the management of primary aldosteronism (PA), following these recommendations may be challenging in developing countries with limited health care access. Objective We aimed to assess availability and affordability resources managing PA Association Southeast Asian Nations (ASEAN) region, which includes low-middle-income countries. Methods instituted a questionnaire-based survey specialists PA, assessing investigations treatment....

10.1210/clinem/dgae039 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2024-01-20

A 40-YR-OLD diabetic, normotensive man presented with weight loss and epigastric discomfort for 6 months. Chest x-ray was normal. Computed tomography (CT) scan revealed bilateral adrenal masses (Fig. 1A). The second patient, a 58-yr-old hypertensive, nondiabetic man, anorexia 5 mediastinal widening. CT showed aortic dissection without lymphadenopathy incidental 1B). Both patients had no history of tuberculosis; their HIV serology negative. 250g cosyntropin stimulation test abnormal in the...

10.1210/jc.2005-1868 article EN The Journal of Clinical Endocrinology & Metabolism 2005-12-01

Objectives. To determine the skin and subcutaneous thickness of adult diabetic Filipinos using ultrasonography. Methodology. We studied 293 Filipino adults who had ultrasonographic measurements their (ST) (SCT) at common insulin injection sites. Results. The mean ST ranges from 1.76 mm to 2.75mm. SCT 6.91 19.1 mm. anterior thigh area has thinnest SCT. On other hand, buttocks have thickest abdomen multiple regression analysis, predictors for are site, age, BMI, gender use, however overall...

10.15605/jafes.029.01.04 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2014-05-31

Presentation of anaplastic thyroid carcinoma with thyrotoxicosis is extremely rare and its occurrence in a patient Wegener's granulomatosis has not been reported previously. We describe an elderly lady who developed rapidly growing preexisting multinodular goiter discuss the mechanism this patient.

10.1089/105072504773297902 article EN Thyroid 2004-03-01

The traditional binary classification of gender is repeatedly challenged throughout history with the presence transgenders.  Under umbrella transgenderism transsexualism which pertains to individuals who identify or desire become opposite sex.  Transsexualism Gender Dysphoria classified as a medical condition under ICD 10 and DSM-5.  The proposed treatment sex reassignment that includes all treatments carried out adapt desired  Sex involves multidisciplinary approach wherein psychiatrist...

10.15605/jafes.028.02.09 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2013-11-30

Abstract Introduction: Epidemiologic observations have suggested a protective effect of soybeans against number epithelial cancers including oral malignancies and by inference precursor lesions such as leukoplakia. Several compounds in shown activity preclinical models; we focused our studies on BBI (Bowman-Birk inhibitor), which is active the protease chymotrypsin. Our phase I trial demonstrated very low toxicity profile 31% response rate 1-month nonrandomized study that was associated with...

10.1158/1940-6207.prev-10-cn02-05 article EN Cancer Prevention Research 2010-12-01

Abstract Background The diagnosis of primary aldosteronism (PA) is comprehensive, which includes case-detection testing, case confirmation followed by subtype classification. In certain instances, such as in the setting spontaneous hypokalemia, suppressed renin activity (PRA) plus plasma aldosterone concentration (PAC) > 15 ng/dL, one may not proceed with confirmatory tests. However, quality evidence behind this approach very low. This study sought to evaluate proposed “simplified...

10.1186/s12902-024-01638-w article EN cc-by BMC Endocrine Disorders 2024-07-08

Abstract Background Pembrolizumab is an anti-programmed death 1 (PD-1) antibody designed to incite immune response against malignant cells. By virtue of this mechanism action, its use has given rise immune-related adverse events including those affecting the endocrine system. Adrenal insufficiency can occur rarely with anti-PD-1 therapy, and symptoms are usually non-specific. Clinical Case An 80-year-old male, known case non-small cell lung cancer stage IV presented a 2-week history...

10.1210/jendso/bvaa046.703 article EN cc-by-nc-nd Journal of the Endocrine Society 2020-04-01

Background: Thyroid incidentalomas detected by 18 F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) have been reported in 1.1 to 2.9% of scans performed. Previous studies determined the prevalence thyroid malignancy these patients be 14-72%. Objective: We undertook a retrospective study determine our center, and evaluated corresponding for patients. Results: A total 2,912 FDG-PET were performed on 1,855 patients, which 56 (3.0%) presented with incidentaloma (40 focal 16 diffuse)....

10.3860/pjim.v47i2.1645 article EN Philippine Journal of Internal Medicine 2010-07-23

Assess safety and effectiveness of liraglutide among Filipino participants with type 2 diabetes (T2D) in routine clinical practice. A 26-week, prospective, multicenter, open-label, observational study was conducted adults T2D prescribed (1.2 mg or 1.8 mg) practice the Philippines. Primary endpoint: incidence rate serious adverse drug reactions (SADRs). Secondary endpoints included other aspects safety, effectiveness. Participants (n=1056) had a mean (standard deviation) age 53.2 (12.0)...

10.15605/jafes.033.02.02 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2018-10-09

Abstract Aim Although Graves’ disease (GD) is common in endocrine practices worldwide, global differences diagnosis and management remain. We sought to assess the current for GD countries across Asia Pacific (APAC), compare these with previously published surveys from North-America Europe. Methods A web-based survey on was conducted a pool of practicing physicians. Responses 542 eligible physicians were received subsequently analysed compared outcomes other, similar surveys. Results During...

10.21203/rs.3.rs-1857328/v1 preprint EN cc-by Research Square (Research Square) 2022-07-19

Abstract In the context of diabetes, clinical inertia is defined as failure to initiate insulin therapy or its intensification when treatment goals have not been met. Patient-related factors that contribute this phenomenon include inability follow complex regimens, cost and drug side effects. Icodec a novel, investigational, ultra-long acting, once-weekly analog with potential for better adherence. However, early evidence from phase 2 trials on icodec in type diabetes mellitus (T2D)...

10.1210/jendso/bvac150.590 article EN cc-by-nc-nd Journal of the Endocrine Society 2022-11-01

Abstract Background Sclerosing Epithelioid Fibrosarcoma (SEF) is a rare form of soft tissue sarcoma, often presenting in the tissues extremities. This tumor characterized by slow growth, with local recurrences and/or distant metastases. First described 1995, subsequent case reports and series have demonstrated that metastases are primarily to lung, pleura bone, but can occur anywhere. Treatment wide excision adjuvant chemotherapy or radiotherapy. However, treatment this sarcoma...

10.1210/jendso/bvac150.1842 article EN cc-by-nc-nd Journal of the Endocrine Society 2022-11-01

A 56-year-old Filipino male presented with bilateral lower limb swelling. The patient was a known smoker one-year history of Graves’ disease. He initially treated methimazole for control thyrotoxicosis. Five months prior to consultation, he given oral radioactive iodine (Iodine-131) the definitive treatment his thyroid

10.15605/jafes.026.01.16 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2011-05-31

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.90.ep853 article EN Endocrine Abstracts 2023-05-02

Abstract Disclosure: A.C. Ong Lopez: None. D.M. Dimayuga: L.E. Tiu: O.C. Dampil: E. Mendoza: M.L. Villa: A.M. Macabuag-Oliva: Background and Objective: The diagnosis of primary aldosteronism (PA) is comprehensive which includes case-detecting testing, case confirmation followed by subtype classification. In certain instances, one may not proceed with further confirmatory testing in the setting spontaneous hypokalemia, suppressed renin, PAC > 15 ng/dL. However, this quality evidence...

10.1210/jendso/bvad114.586 article EN cc-by-nc-nd Journal of the Endocrine Society 2023-10-01

Abstract Disclosure: O.C. Reyes: None. A. Sison: M. Villa: D. Dimayuga: Introduction: Adrenocorticotropic hormone-producing pancreatic neuroendocrine neoplasm (ACTHoma) is a rare type of tumor that causes ectopic adrenocorticotropic hormone syndrome. Cushingoid manifestations and metabolic abnormalities can occur rapidly. High index suspicion required for early diagnosis. Case: A 31-year-old Filipino female presented with facial ankle swelling occurred 6 weeks before the visit. She also had...

10.1210/jendso/bvad114.2145 article EN cc-by-nc-nd Journal of the Endocrine Society 2023-10-01

Bilateral Adrenal Lymphoma is a rare disease which, when it discovered, may be associated with adrenal insufficiency. We report case of an 81-year-old female, no known co-morbidities, presenting anorexia and flank pain. Initial CT imaging revealed bilateral masses measuring 6.4 x 7.4 cm on the right 5.9 5.8 left subsequent scans showing to rapidly enlarging.  Aspiration biopsy Non-Hodgkin’s Lymphoma, diffuse large B cell type.  She underwent chemotherapy almost complete resolution tumors.

10.15605/jafes.027.02.16 article EN cc-by-nc Journal of the ASEAN Federation of Endocrine Societies 2012-11-30

Case history A 61-year-old woman was referred for further assessment of her chronic obstructive pulmonary disease (COPD). She had been diagnosed 5 years previously following a chest infection. Her symptoms consisted an occasional cough and she UK Medical Research Council dyspnoea score 3 out 5. denied haemoptysis or weight change. no signifi cant past medical with background atopy childhood disease. father mother both winter bronchitis. ex-smoker 37 pack-year history. The patient suffered...

10.1183/18106838.0504.363 article EN cc-by-nc Breathe 2009-01-01

Abstract Introduction: Parathyroid carcinoma is rare, affecting less than 1% of patients with primary hyperparathyroidism (PHPT). 1 concomitant papillary thyroid also and the etiology not fully defined. Clinical Case: We present 3 parathyroid discuss their presenting symptoms, characteristics, treatment. Two women man (2 Filipinos Marshallese) age range 53-68 years old had carcinoma. hyperparathyroidism, one non-functioning type bone or renal disease. All three concurrent disease- 2...

10.1210/jendso/bvaa046.835 article EN cc-by-nc-nd Journal of the Endocrine Society 2020-04-01

Abstract Hypercalcemia in hyperthyroidism is usually asymptomatic, and related to a concurrent primary hyperparathyroidism. In this report, we describe case of symptomatic hypercalcemia secondary Graves’ disease alone. Case Report. A 24-year-old Filipino female presented the emergency department with generalized weakness, vomiting abdominal pain. No other symptoms were noted. She was otherwise previously healthy. Family history unremarkable. During physical exam, she noted have non tender...

10.1210/jendso/bvaa046.025 article EN cc-by-nc-nd Journal of the Endocrine Society 2020-04-01

Abstract Background Uncontrolled Graves’ disease is associated with significant morbidity and mortality. Treatment of such patients who have developed multi-organ dysfunction challenging, novel interventions to be explored. We present a case uncontrolled thyrotoxicosis cardiogenic shock hepatic successfully controlled using therapeutic plasma exchange as bridge definitive management total thyroidectomy. Case Presentation Our patient 36-year-old Filipina known for three years but poor...

10.1210/jendso/bvac150.1635 article EN cc-by-nc-nd Journal of the Endocrine Society 2022-11-01
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