A5030348495- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Air Quality Monitoring and Forecasting
- Prostate Cancer Treatment and Research
- Fire effects on ecosystems
- Health, Environment, Cognitive Aging
- Computational Drug Discovery Methods
- Cancer Genomics and Diagnostics
- Urban Heat Island Mitigation
- Big Data Technologies and Applications
- Estrogen and related hormone effects
- Sexual Differentiation and Disorders
- Genomics and Rare Diseases
- Atmospheric and Environmental Gas Dynamics
- Wildlife Ecology and Conservation
- Prostate Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Hormonal and reproductive studies
- Human Mobility and Location-Based Analysis
- Cancer, Lipids, and Metabolism
- Zoonotic diseases and public health
- Pesticide Exposure and Toxicity
- Smart Cities and Technologies
- Atmospheric chemistry and aerosols
- Radiopharmaceutical Chemistry and Applications
BC Centre for Disease Control
2021-2025
University of British Columbia
2016-2023
Background: There is increasing evidence that long-term exposure to fine particulate matter [PM ≤2.5μm in aerodynamic diameter (PM2.5)] may adversely impact cognitive performance. Wildfire smoke one of the biggest sources PM2.5 and concentrations are likely increase under climate change. However, little known about how short-term impacts function. Objectives: We aimed evaluate associations between daily subdaily (hourly) wildfire performance adults. Methods: Scores from 20 plays an...
Exposure to biomass smoke has been associated with a wide range of acute and chronic health outcomes. Over the past decades, frequency intensity wildfires increased in many areas, resulting longer episodes higher concentrations fine particulate matter (PM2.5). There are also communities where seasonal open burning residential wood heating have short- long-term impacts on ambient air quality. Understanding effects exposure requires reliable estimates PM2.5 during wildfire season throughout...
Human populations and ecosystems are extensively exposed to pesticides. Most nations lack the capacity control pesticide contamination have limited availability of use information. Ecuador is a country with intense high exposure risks humans environment, although relative or combined not well understood. Here, we analyzed distribution application rates in identified regions concern because potential exposure. We used geospatial analysis identify grid cells (∼8 km × 8 km) where highest...
The human androgen receptor (AR) is a ligand-activated transcription factor that plays pivotal role in the development and progression of prostate cancer (PCa). Many forms castration-resistant (CRPC) still rely on AR for survival. Currently used antiandrogens face clinical limitations as drug resistance develops patients over time since they all target mutation-prone binding site (ABS), where gain-of-function mutations eventually convert antagonists into agonists. With significant number...
A growing body of evidence indicates that exposure to air pollution affects cognitive performance; however, few studies have assessed this in the context repeated measures within a large group individuals or population with age range. In study, we evaluated associations between long-term fine particulate matter (PM2.5) and ozone (O3) cohort adults aged 18-90 years. The study included 29,091 Lumosity users contiguous US who completed 20 repetitions Lost Migration game 2017 2018. Game scores...
Epidemiological studies typically model wildfire smoke exposure by predicting outdoor fine particulate matter (PM2.5) concentrations, overlooking indoor environments where people spend most of their time. This discrepancy can lead to misclassification for and other air pollutants. We developed a machine learning (ML) estimating daily PM2.5 concentrations in British Columbia, Canada, using an ensemble nonparametric ML algorithms during the 2022 2023 seasons. For training, we included...
Exposure to biomass smoke has been associated with a wide range of acute and chronic health outcomes. Over the past decades, frequency intensity wildfires increased in many areas, resulting longer episodes higher concentrations fine particulate matter (PM 2.5 ). There are also communities where seasonal open burning residential wood heating have short- long-term impacts on ambient air quality. Understanding effects exposure requires reliable estimates PM during wildfire season throughout...
BACKGROUND AND AIM: A growing body of evidence indicates that exposure to air pollution affects cognitive performance; however, few studies have assessed this in the context repeated measures within a large group individuals. To evaluate association between long-term ambient and aspects function we used performance data from mobile Lumosity brain training platform. METHODS: The study cohort included 29,091 users contiguous US who completed 20 repetitions Lost Migration game 2017 2018. Game...
BACKGROUND AND AIM: There is increasing evidence that air pollution exposure adversely impacts cognitive health. While wildfire smoke a pollutant of growing concern, there little to date if short-term function. Using repeated measures, we aimed identify and quantify the relationship between daily sub-daily PM₂.₅ changes in performance adults. METHODS: Cognitive data was obtained for 1,467 Lumosity users, age 18+, who completed 20 plays brain-training game targeted improve flexibility western...