Aim of the study was to evaluate patient and graft survival after liver transplantation (LT) determine if primary disease diagnosis, early dysfunction or other factors affect it. Furthermore, we analyzed reasons short-term long-term deaths retransplantations. Materials methods . 192 LTs from donors with brain death were performed December 2004 until June 2014. Recipient age varied 5 71 years. Most frequent diagnosis cirrhosis (mainly due hepatitis C), then hepatocellular carcinoma (HCC),...

Donor organs shortage leads to extending criteria for deceased liver donation in the whole world. Aim: compare results of donor transplantation (DDLT) depending age over 60 years old. Materials and methods: study includes 390 DDLT from January 2010 November 2017. All donors separated by two groups: I – older (n = 26); II younger than 364). were standardized demographic, laboratory fi ndings inotropic drug requirement. Results: no difference between both groups severity ischemia-reperfusion...

Aim. The aim of this study focuses on the fi rst experience with self-expandable stents, analysis its ef cacy and safety in treatment anastomotic strictures after liver transplantation. Materials methods. There’re 136 transplantations performed from 2004 till 2012. To correct we’ve used only coated nitinol stent. We stenting 7 recipient. Result. In 131 transplant recipi ents incidence biliary has been 5.3%. All 5 patients have managed by retrograde or antegrade way. Conclusion. Our first...

This article provides an overview of new approaches to the prevention infectious complications bacterial nature after high-technology operations in abdominal surgery, fi rst all, liver transplantation. At- tention is drawn positive results randomized studies on use biological preparations - probi- otics, prebiotics and synbiotics patients The authors prove prospects further development this subject based successful model experiments animals various operational interven- tions surgery.

The study was carried out to investigate etiology and rate of prevalence nosocomial strains microbes in biosubstrates patients case development infectious complications level their resistance various groups antibiotics. retrospective analysis agents post-operational sensitivity antibiotics 99 after operations transplantation liver kidneys 2013. were allocated on three groups: group I - department reanimation intensive therapy mentioned (17 individuals); II (42 individuals) orthotopic (19...

The aim of this study was to evaluate our experience on laparoscopic living donor nephrectomy (LDN). During the last 1,5 years we have gradually expanded use minimally invasive LDN with various techniques: strictly and hand-assisted laparoscopic. This comparative is based 250 conventional open 61 LDN. Minimally technique shown be associated a signi fi cantly lower risk major complications intraoperative incidents, as well reduced warm ische- mia operative time. There no negative impact...

There’s a report of 100 cadaveric liver transplantation performed from December 2004 to June 2011. Indication for transplantation, including retransplantation, technical features surgery, postoperative complications have been described. Patient survival was significantly lower in HCV-positive and HCC recipient than other indications. Cumulative rate at 1, 3, 5 years is 89; 87; 87%. graft 85; 82; 70%. Long term immunosupression HCV-infection after are discussed.

Bone mineral density (BMD) was estimated twice in 18 recipents of ortotopic liver transplantation. There decreased BMD axial so as peripheral skeleton early time and vertebral or hip Ward triangle late following transplantation being lower primary biliary cirrosis then chronic virus hepatitis despite tacrolimus immunosupression without prednisolon. Tacrolimus with prednisolon patients postoperative associated hard lowering which correlated glucocorticoid therapy duration cumulative dosis.

Evaluate the cost-effectiveness of various options for supply direct antiviral agents patients with chronic viral hepatitis C. An analysis data Moscow Department Health on drug C drugs at expense budgetary funds in was carried out. The medical costs urban healthcare system use action period from 2017 to 2019 were calculated. For 2019, 6,936 received medication budget Moscow. increase number compared base (2017) year noted by 76%, as well an volume interferon-free therapy sets against...

Aim: of our clinical study was to present own experience veno-venous extracorporeal membrane oxygenation (VV ECMO) for the treatment an adult patient (female, 28 yrs, 150 cm, 35 kg) with acute respiratory distress syndrome (ARDS) in early period after liver transplantation against satisfactory graft function. Materials and methods. Double-lumen cannula 22 F placed percutaneously right internal jugular vein. The ext- racorporeal contour reduced length polymethylpeptene oxygenator (priming...

Aim. Comparative evaluation of two biochemical markers bone resorption and hormonal regulation metabolism in liver recipients. Methods results. B о ne densitometry L2–L4 neck femur, serum level some hormones (PTH, vitamin D 3 , estradiol, testosterone) regulating osteoclastogenesis as well com- parative analyses β -crosslaps tartrate-resistant acid phosphatase type 5b (TRAP-5b) were ful fi lled patients after orthotopic transplantation (OLT). In 1 month OLT density reduction femur; decrease...

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Methods and results: bone densitometry of L2-L4 neck femur, the level in serum blood some hormones (PTH, vitamin D3, estradiol, testosterone) cytokines (OPG, IL-6, FNO-a) regulating osteoclastogenesis as well comparative analyses two resorption markers β-crosslaps tartrate-resistant acid phosphatase type 5b (TRAP-5b) were fulfilled at different periods following orthotopic liver transplantation. At early date after operation there density decrease L2-L4, lowering estradiol women,...

Axial and periferal bone mineral density (BMD) was estimated by DXA twice within 1-47 months in 16 patients following orthotopic liver transplantation (OLT). Osteoporosis osteopenia of lumbar spine hip were identified the first examination all 9 recipients (group 1) with primary biliary cirrhosis (PBC) 5 out 7 (71%) viral hepatitic 2). Recipients which firstly examined 1-7 OLT (subgroups 1A, 2A) through 9±2.8 showed 1A axial BMD elevation (on 20.7+13.2% ; P=0.024) 2A so as 10.5+2.7%;P=0.001...

24 recipients after ortotopic liver transplantation (9 women and 5 men) 18–57 years aged were studied in 1–2 then through 4–18 months following operation. Bone mineral density (BMD) repeated estimation 13 was elevated on 14 ± 10,5% 11 decreased 2,5 2,56%. BMD elevation associated with bone remodelling normalization. lowering followed transplant dysfunction, glucocorticoid therapy, resorption increasing formation suppression.

Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid type 1 procollagen (P1NP), isoferment alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal BALP without clinical postoperative complication; lower as a result corticosteroid therapy prior/ following transplantation; superior which results excessive accumulation hepatic...

Orthotopic liver transplantation is the only way to cure chronic failure and certain tumors. Deceased donor organs are prevailing source in most centers. However, there an organ shortage because of increasing number patients need transplantation. Using expanded criteria deceased donors a routine overcome shortage. The majority centers take older depending on local rules. Successful from 73-year-old donor. Recipient suffered neuroendocrine tumor without signs extrahepatic spread. Liver...