A5020266770- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Organ and Tissue Transplantation Research
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Kidney Injury Research
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Viral Infections and Immunology Research
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Macrophage Migration Inhibitory Factor
- Cardiac Health and Mental Health
- Liver Disease Diagnosis and Treatment
- Congenital Anomalies and Fetal Surgery
- Infective Endocarditis Diagnosis and Management
- Cystic Fibrosis Research Advances
- Organ Donation and Transplantation
V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs
2016-2025
Research Medical Center
2025
Federal Research Centre of Nutrition and Biotechnology
2024
Medical Technologies (Czechia)
2008
For many decades, heart transplantation has been the “gold standard” for terminal chronic failure resistant to medical therapy treatment. However, there is a significant number of patients with contraindications orthotopic transplantation. The only effective treatment method these may be implantation long-term mechanical circulatory support systems. This article provides information practicing physicians on evolution systems, main criteria selecting implantation, and specifics their...
Mechanical circulatory support (MCS) is the only way to save a life for heart transplant candidates and decrease of waiting list mortality. The choice between short- or long-term pretransplant MCS depends on type severity CHF. One most frequently used methods temporary MSC before orthotopic transplantation (OHTx) veno-arterial extracorporeal membrane oxygenation (VA ECMO). aim this study was analyze own experience peripheral VA ECMO (pVA ECMO) in needed urgent HT.This included 182 pts [160...
Introduction . Over the past few decades in Russia and other countries there has been signifi cant progress development of liver transplantation children. It became possible to operate recipients with very low body mass, perform transplant from cadaveric living donors incompatible blood type, as well single-step kidney or pancreas patients combined diseases. Aim: investigate 6-year experience children V.I. Shumakov Federal Research Center Transplantology Artifi cial Organs. Materials...
We present 38-years male patient. He has suffered from muscle weakness since 5 years. Arrhythmias appeared at the age of 32. In 37 years he had sick sinus syndrome, transient AV block II degree, paroxysmal atrial fibrillation, flutter, ventricular arrhythmias. At this time, dilated cardiomyopathy was also detected. The evaluation revealed knees and elbows contractures, increased level creatine kinase. genetic testing a frame shift deletion c.del619C in emerin (EMD) gene c.IVS4-13T> A lamin...
Aim of the study was to evaluate patient and graft survival after liver transplantation (LT) determine if primary disease diagnosis, early dysfunction or other factors affect it. Furthermore, we analyzed reasons short-term long-term deaths retransplantations. Materials methods . 192 LTs from donors with brain death were performed December 2004 until June 2014. Recipient age varied 5 71 years. Most frequent diagnosis cirrhosis (mainly due hepatitis C), then hepatocellular carcinoma (HCC),...
Objective : comparative analysis of long-term outcomes following heart transplantation (HT) with prolonged and short cold ischemia. Materials methods . We analyzed the data 29 orthotopic HT >4 hours The transplant surgery was performed at Meshalkin National Medical Research Center between 2013 present time. Organs were obtained from donors other regions. control group consisted HTs ischemia <4 hours, in same period. minimum distance center donor base about 250 km (Barnaul); maximum 850...
Adherence to proper indications for red blood cells (RBC) transfusion is essential because of its potential adverse effects and costs therapy. Aim these recommendations summarize typed RBC concentrates transfusions among different categories the patients. Methods. The methodological approaches are based on Russian expert council (leading specialists Federation) literature search randomized clinical trials evaluating storage duration, hemoglobin thresholds without language restrictions....
The paper describes the fi rst clinical experience in RF of successful application domestic circulatory support device based on implantable axial pump for two stage heart transplantation. This case demonstrate effec- tiveness and safety our ( АВК - Н ) a longtime (270 days) left ventricular bypass ability to perform transplantation donor , s after this system.
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High-tech methods of surgical treatment cardiac patients older than 65 years are the only means ineffectiveness drug treatments prolong their life and improve its quality. The analysis postoperative period 5 (2009 - 2013) compared with up to years. study used epidemiological microbiological methods. frequency infectious complications was higher in In structure pathogens isolated from blood dominated negative bacteria: Acinetobacter spp., Klebsiella Pseudomonas aeruginosa. There a trend...
Aim: the aim of study was a comparative assessment quality life recipients with donor heart at stages before and after transplantation. Materials methods : included 150 patients who underwent orthotopic transplantation «Academician V.I. Shumakov National Medical Research Center Transplantology Artificial Organs», Ministry Health Russian Federation from January 2009 to March 2018. Results. Analysis research results indicates extremely low rates both physical activity overall health...
The analysis of clinical outcomes cardiac transplantation is presented. main directions research on the development and implementation methods for early diagnosis adverse events treatment patients with heart transplant in V.I. Shumakov Federal Research Center Transplantology Artifi cial Organs Ministry Healthcare Russian Federation are given. Among non-invasive forecasting, assessment risk cardiovascular complications recipients being developed are: laboratory biomarkers involved formation...
Heart transplantation (HT) is considered the optimal therapy for end-stage heart failure. In recent years, number of operations performed has been growing, which led to a rise in transplant recipients requiring outpatient follow-up. Objective: evaluate effectiveness model dual personalized follow-up consultative and diagnostic department Shumakov National Medical Research Center Transplantology Artificial Organs. Materials methods . The study included 1,436 patients under from January 2008...
Diabetes mellitus is one of the most prevalent chronic metabolic disorders. Its role in patients with heart transplantation not unifi ed. According to some authors, post-transplantation diabetes increases risk acute rejections and infections, incidence coronary artery disease graft reduces long-term survival transplantation. On other hand studies did confi rm these fi ndings. However, when diabetic were stratifi ed by severity, recipients less severe achieved better survival. Accordingly,...
We herein present our initial report from «ROKKOR-recipient», a national multicenter observational study. The prevalence, risk factors, clinical manifestations and outcomes of the novel coronavirus disease 2019 (COVID-19) in solid organ transplant recipients receiving immunosuppressive therapy were investigated. study enrolled 251 COVID-19 patients (220 kidney recipients, 7 liver 1 liver-kidney recipient, 23 heart recipients). subjects came 20 regions Russia. symptoms, presentation, imaging...
In the current situation of shortage suitable donor organs, heart transplantation from older donors is one ways to increase performance more transplants, particularly, in patients with urgent need transplantation. While planning a should consider increased risk early cardiac allograft dysfunction, preexisting coronary artery disease, accelerated transplant vasculopathy which may adversely affect and long-term survival recipients. Subject careful selection donor–recipient pairs, effective...
Aim: to develop an optimal surgical tactic for implantation of “AVK-N” system as a “bridge” heart transplantation. Materials and methods. 17 patients were included. They operated in the period from 2012 October 2017 Federal State Budgetary Institution «V.I. Shumakov National Medical Research Center Transplantology Artifi cial Organs». A tiny implantable «Portable device assisting cardiac circulation» (AVK-N; Russia) was used replacing pumping function left ventricle. All examined according...
The effi ciency of lung transplantation is considerably limited by the complications associated with bronchial pathologies. Despite progress treatment methods, are still remaining as an actual problem in postoperative period frequency occurrence from 7 to 29%. However, stenosis most common after mortality 2 4%. Aim. To study experience our center recipients. Materials and methods. 34 patients underwent September 2014 January 2017. 6 (16%) them had a lobar or segmental bronchi 84 494 day. 5...
Combined heart-kidney transplantation may be performed in carefully selected patients with end-stage heart disease and renal failure. There are two types of combined kidney: 1) simultaneous (SHKT) from the same donor; 2) staged kidneys genetically different donors. The ISHLT registry 2014 reported an increase number SHKT over years: 22 1994 to 97 2012. World experience demonstrated excellent results SHKT. Recipients had superior survival, lower rates acute cardiac rejection compared...
Heart transplantation remains the gold standard treatment for end-stage heart failure. Lifelong immunosuppressive and adjuvant therapy requires constant medical follow-up in order to optimize regimens increase adherence of recipients treatment. Objective: study adapt a method systematic assessment complexity regimen using MRCI index, its link long-term prognosis recipients. Materials methods. Results were obtained by analyzing data observed at Consultative & Diagnostic Department,...
Objective: to analyze heart transplant (HT) outcomes in patients who suffered cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR) by peripheral veno-arterial membrane oxygenation (VA-ECMO). Materials and methods. The study included 41 (14 (34.1%) women 27 (65.9%) men, aged 42.6 ± 16.8 (40.0 [30.5; 54.0]) years with in-hospital arrest. causes of were acute decompensated failure (n = 19; 46.3%), irreversible graft dysfunction 9; 22.0%), postcardiotomy 5; 12.2%),...