- Lymphoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Chronic Lymphocytic Leukemia Research
- Telomeres, Telomerase, and Senescence
- Gastrointestinal Tumor Research and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Cancer Immunotherapy and Biomarkers
- Malaria Research and Control
- Cutaneous lymphoproliferative disorders research
- Neuroendocrine Tumor Research Advances
- Immune Cell Function and Interaction
- Platelet Disorders and Treatments
- Colorectal Cancer Treatments and Studies
- Cytomegalovirus and herpesvirus research
- CAR-T cell therapy research
- Aquaculture Nutrition and Growth
- Kawasaki Disease and Coronary Complications
- Phytochemicals and Medicinal Plants
- Leprosy Research and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Obesity and Health Practices
- Renal function and acid-base balance
- Complement system in diseases
- Postcolonial and Cultural Literary Studies
Einstein Medical Center Philadelphia
2022-2024
Philadelphia College of Osteopathic Medicine
2024
Mankind Pharma (India)
2024
Jefferson Hospital
2024
Thomas Jefferson University
2024
Einstein Healthcare Network
2023
Drexel University
2011-2019
Manipal Hospital
2014-2017
Albert Einstein College of Medicine
2016
Montefiore Medical Center
2016
Aging is the main risk factor for Alzheimer's disease (AD); however, aspects of aging process that predispose brain to development AD are largely unknown. Astrocytes perform a myriad functions in central nervous system maintain homeostasis and support neuronal function. In vitro, human astrocytes highly sensitive oxidative stress trigger senescence program when faced with multiple types stress. order determine whether senescent appear vivo, tissue from aged individuals patients was examined...
Organic acids have emerged as promising alternatives to antibiotic growth promoters in poultry production. The present study was conducted determine the effects of organic blends v.i.z. Acidapure liquid and powder supplementation on performance, gut health, microbiota, serum lipid profile broiler chickens. A total 120-day-old chicks with similar live body weights were randomly divided into four groups. Each group further 3 replicates, each three replicates ten bird. birds Group 1 (T1) fed a...
Anti-melanoma differentiation-associated gene 5 antibody (anti-MDA-5 Ab) is associated with amyopathic dermatomyositis (DM). These patients are particularly at high-risk for developing acute and rapidly progressive interstitial lung disease (ILD). Given the lack of muscle-related symptoms, along its sudden onset rapid clinical progression, diagnosis anti-MDA-5 Ab + ILD represents a challenge clinicians. Even after established, prognosis remains dismal owing to hyperinflammatory state,...
Mean platelet volume (MPV), distribution width (PDW) and the calculated plateletcrit (PCT) are reported to be useful in thrombocytopenia assess regeneration marrow. Our hypothesis was that immature fraction (IPF) is most significant parameter patients with thrombocytopenia. Seven hundred twenty-two consecutive CBCs were analyzed on Sysmex XN1000 (Sysmex Corporation, Kobe, Japan) using PLT-F channel. …
Five proteins from the soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) complex family were studied in normal hematopoietic cells bone marrow; lymphocytes at different stages of maturation and differentiation marrow, thymus, tonsil, lymph node; malignant lymphomas; leukemias.Sixty-eight reactive 380 lymphoid neoplasms immunohistochemically stained for syntaxin 7 (STX7), vesicle-associated membrane (VAMP2, VAMP7, VAMP8), synaptosomal-associated 23 (SNAP23).STX7...
Gitelman's syndrome is a primary renal tubular hypokalaemic metabolic alkalosis with hypocalciuria and hypomagnesaemia, mild variant of Bartter's syndrome.
A promising alternative strategy for the treatment of glioblastoma multiforme (GBM) is use oncolytic viruses (OVs) that specifically replicate in and destroy tumor cells. In addition to direct oncolysis, OVs offer chance induction anti-tumor immune effects can be combined with standard therapies. Parvovirus H-1 (H-1PV) a small single-stranded DNA virus rodent origin anti-glioma properties rat models. Intratumoral intravenous infection led cure orthotopic gliomas while at same time raising an...
Adult-onset Still’s disease (AOSD) is a rare multi-systemic inflammatory disorder characterized by high spiking fevers, nonpruritic, salmon-colored rash, and severe polyarthralgia. Laboratory features typically include elevation in white blood cells, liver enzymes, ferritin. Central nervous system cardiac involvements, particularly myocarditis, are rare. Macrophage activation syndrome (MAS) well-described complication of AOSD, leading to mortality rate. Herein, we describe case AOSD...
A 49-year-old African male receiving chemotherapy for stage 4 mucinous adenocarcinoma of the colon, presented with generalized weakness, fever and chills days. full blood count showed: white cell 9·03 × 109/l, haemoglobin concentration 93 g/l platelet 194 109/l as measured by fluorescence channel Sysmex XN 1000 (Sysmex Corporation, Kobe, Japan), an immature fraction 70·1% (left, arrow). However, a peripheral film showed low numbers presence Plasmodium falciparum schizonts, ring forms...
Mycosis fungoides and Sézary syndrome are indolent cutaneous T-cell lymphomas, with skin-associated peripheral lymph nodes being the most frequent extracutaneous site of involvement. Acquisition functional properties regulatory T-cells by malignant in advanced disease may contribute to immunosuppression. Whereas previous studies examining FoxP3 protein expression mycosis have focused on skin specimens, little data available from patients these conditions. In this study we examined FoxP3+ 26...