A5101646760- Synthesis and bioactivity of alkaloids
- Protein Degradation and Inhibitors
- Cancer therapeutics and mechanisms
- Synthesis and Biological Evaluation
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Ubiquitin and proteasome pathways
- Cancer-related gene regulation
- Autophagy in Disease and Therapy
- Histone Deacetylase Inhibitors Research
- Ferroptosis and cancer prognosis
- Quinazolinone synthesis and applications
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Epigenetics and DNA Methylation
- Cancer Mechanisms and Therapy
- Hemodynamic Monitoring and Therapy
- Radiation Dose and Imaging
- Medicinal Plant Pharmacodynamics Research
- Electrical and Bioimpedance Tomography
- PI3K/AKT/mTOR signaling in cancer
- Pharmacological Effects of Natural Compounds
- Endoplasmic Reticulum Stress and Disease
- Ultrasound in Clinical Applications
- Traditional Chinese Medicine Analysis
First Affiliated Hospital of Gannan Medical University
2022-2024
Shenyang Pharmaceutical University
2022
General Hospital of Shenyang Military Region
2022
Taihe Hospital
2020-2021
Hubei University of Medicine
2020-2021
Zhengzhou City Hospital
2018
National Institute for Radiological Protection
1985-1992
Gastric cancer (GC) is a leading cause of cancer-related death with poor prognosis. Growing evidence has shown that long noncoding ribonucleic acid (lncRNA) FEZ family zinc finger 1 antisense RNA 1(FEZF1-AS1), an "oncogene," regulates tumor progression and supports stem cell. However, the tumorigenic mechanism FEZF1-AS1 on gastric cell (GCSC) yet to be investigated. Here, we discovered was upregulated in GC tissues lines. Knockdown inhibited sphere formation decreased expression factors...
Multidrug resistance (MDR) is considered as a primary hindrance for paclitaxel failure in non-small cell lung cancer (NSCLC) patients, which P-glycoprotein (P-gp) overexpressed and the PI3K/Akt signaling pathway dysregulated. Previously, we designed synthesized DHW-221, dual PI3K/mTOR inhibitor, exerts remarkable antitumor potency NSCLC cells, but its effects underlying mechanisms resistant cells remain unknown. Here, reported first time that DHW-221 had favorable antiproliferative activity...
Autophagy plays a key role in the development of non-small-cell lung cancer (NSCLC). Beclin-1 is essential for initiation and regulation autophagy. Accumulated studies have investigated prognostic NSCLC, but conclusions remain controversial. Therefore, we conducted this meta-analysis to assess potential significance NSCLC.PubMed Embase databases were searched eligible published before December 31, 2017. Odds ratio (OR) was pooled evaluate clinicopathological NSCLC. Hazard (HR) adopted...
Abstract Objective To explore the value of bedside ultrasound in monitoring peak flow velocity abdominal aorta and its branches assessing volume status patients with septic shock. Methods A total 80 shock admitted to Foshan Rehabilitation Hospital(The Fifth People’s Hospital Foshan) Guangdong Provincial from June 2022 2023 were selected as research subjects. All treated mechanical ventilation,and deep venous catheters placed internal jugular vein or subclavian monitor central pressure...
After an outline of activities, publications and contributing organizations in the field research biological effects radiations, a brief description to Institute Radiation Protection, MNI, -one with 8 divisions 1 affiliated hospital is given. Then topics more closely connected radiation protection are reviewed. Animal experiments various end points performed determine n gamma RBE's, their additivities examined. In chromosome aberration studies, groups significantly lower natural rates...