The article uses theory and qualitative evidence to show how youth participatory action research (YPAR) can advance educational equity. YPAR engages young people adult allies in on issues their schools communities. Interviews with over two dozen researchers-students partner teachers-elaborate the mechanisms through which school-based affect equity, including direct changes policy practice as a result of actions, school culture that values student experiences, transformative teacher-student...

The antiangiogenic multi-kinase inhibitors (MKIs) apatinib, donafenib, and anlotinib have demonstrated satisfactory efficacy in radioactive iodine refractory differentiated thyroid cancer (RAIR-DTC) their phase II/III trials. However, the potential impact factors on of these MKIs remain unclear. RAIR-DTC patients enrolled clinical trials our center were retrospectively reviewed. Kaplan–Meier method was used to examine relationship between clinicopathological variables progression-free...

OBJECTIVE Hydrocephalus affects approximately 1 in 500 people the US, yet ventricular shunting, gold standard of treatment, has a nearly 85% failure rate. Endoscopic third ventriculostomy (ETV) is an alternative surgical approach for specific subset hydrocephalic patients, but can be limited by inability neurosurgical residents to practice prior patient contact. The goal this study was create affordable ETV model and endoscope resident training. METHODS Open-source software used isolate...

Sevoflurane anesthesia in pregnant mice could induce neurotoxicity the developing brain and disturb learning memory offspring mice. Whether it impair social behaviors is uncertain. Therefore, we assessed neurobehavioral effect of in-utero exposure to sevoflurane on interaction C57BL/6 The were anesthetized with 2.5% 100% oxygen for 2 h, their tested three-chambered paradigm, which includes three 10-min sessions habituation, sociability, preference novelty. At juvenile age, showed abnormal as...

Abstract Purpose Repeated exposures to sevoflurane could induce epigenetic modifications in specific brain regions and cognitive impairments the immature mice. Conflicting findings make neurobehavioral manifestations intricate potential mechanisms elusive. Influence of neonatal anesthesia with on expression synaptic scaffold proteins neuronal activity remains be determined. Methods C57BL/6 male female mice breeding ages were used produce next generation. The offspring randomly scheduled...

Intrathecal catheterization and drug delivery in rats has always been a very important method for neuroscience pain research. Although the technique continually improved since first report, experience gained over years suggested that some defects remained unsolved. On basis of modification standard epidural needle, lumbar intrathecal tube, we aimed to develop simple practical catheterization, which was similar 'needle-through-needle technique' used combined spinal-epidural (CSE)...

The management of breakthrough pain in cancer patients is always a challenge for medical professions. Occurring 80% with advanced disease, significantly decreases both patient's and caregiver's quality life. aim this study to assess the analgesic efficacy fixed inhaled nitrous oxide/oxygen mixture adult pain. This randomized, placebo-controlled, double-blind study; it will be conducted General Hospital Ningxia Medical University. target subjects are at least 18 years old, hospitalized who...

A great number of pediatric patients undergoing varied procedures make neonatal surgery plus anesthesia become a matter concern owing to underlying neurotoxicity in developing brain. The authors set out assess long-term effects mouse model. Six-day-old C57BL/6 mice were randomized receive either with 3% sevoflurane, abdominal under the same anesthesia, or control condition. These examined learning and memory at juvenile age Morris water maze test. brain tissues harvested for Western blot...

Social interaction deficit is core symptom of children with autism, owing to genetic predisposition and environmental toxins. Sevoflurane could induce neurotoxicity in developing brain rodent models. This study aims investigate whether sevoflurane anesthesia neonatal period impair social behaviors male female mice. Twenty-eight thirty-one mice were randomly assigned receive 3.0% or 60% oxygen on postnatal day 6. They tested for at one- two-month-old. In addition, the cortex hippocampus...

This investigation is aimed at gaining a better understanding of the factors that lead to mechanical failure shunts used for treatment hydrocephalus, including shunt catheter-valve disconnection and catheter fracture.

Anesthetic sevoflurane could induce neurotoxicity in developing brain and cause adverse neurobehavioral outcomes mice, including inattention, social interaction deficit, learning memory impairment. However, there is less data on the effect of anesthesia plus surgery behavior. Therefore, we investigated whether combination surgical stimulation behavioral biochemical changes mice. Firstly, six-day-old mice were received either 3% or abdominal under anesthesia. Then, these scheduled to test...

Introduction Postcraniotomy pain protocols use opioids, which are considered suboptimal analgesia following this procedure. Multimodal components sparse. Our null hypothesis states that sumatriptan is not different to placebo in addition usual intravenous for the treatment of acute postcraniotomy pain. Methods and analysis This a prospective single-centre randomised double-blinded placebo-controlled phase III clinical trial comparing subcutaneous injection recovery area with Eligible adult...

Humans constantly interact with their surrounding environments. Current human-centric generative models mainly focus on synthesizing humans plausibly interacting static scenes and objects, while the dynamic human action-reaction synthesis for ubiquitous causal human-human interactions is less explored. Human-human can be regarded as asymmetric actors reactors in atomic interaction periods. In this paper, we comprehensively analyze asymmetric, dynamic, synchronous, detailed nature of propose...

Objective To evaluate the clinical effect of traditional Chinese medicine fumigation and herbal plaster for patients with anal abscess. Methods A total 140 abscess were randomly divided into 2 groups, 70 in each group. The control group treated different operation methods according to patient's health condition. Potassium Permanganate solution (1:5 000) bath was used after surgery conventional anti anti-infection treatment; observation on basis wound both groups following 3 months...

与普通病房静脉输液排气操作比较，手术室麻醉期间静脉输液准备具有特殊性，主要表现在手术室使用管径较粗的输血器代替普通输液器，使用三通阀代替管径很细的头皮针。前者是便于术中必要时快速输液/输血，后者是便于麻醉医生追加药物。另外，手术室麻醉期间的静脉输液操作比较频繁、时间相对紧迫、排气必须成功。鉴于手术室麻醉期间静脉输液准备的特殊性，笔者设计出一套改进的静脉输液排气方法。该方法巧妙地运用流体力学原理，恰当地融入美学元素，将手术室麻醉期间静脉输液排气操作表现得美仑美奂。在保证排气成功的前提下，该方法操作时间短、无液体损失，而且容易掌握，值得在手术室推广。

目的  评价一套新的静脉输液排气改进方法在手术室麻醉期间的实用性。方法  随机邀请新来手术室的实习护士10位，在培训前、培训后2h和培训后1天这3个时间点，分别进行3次静脉输液排气的测试。记录各位实习护士的操作时间，并观察其在培训前静脉输液排气操作上存在的问题。结果  与培训前比较，实习护士在培训后2h和后1天的静脉输液排气操作时间缩短，差异有统计学意义（ P ＜ 0.0001， ＝0.0001），并且测试成绩稳定。结论  经笔者改进的静脉输液排气方法，除了保证排气成功外，能有效缩短排气操作时间，并且易被实习护士掌握。该方法实用价值较高，值得在手术室推广。

Objective: The objective is to study the approach of removal craniopharynginoma. Methods: We remove eight cases craniopharynginoma in childhood which intrudes third ventricle transcallosal septum pellucidum interforniceal from August, 2013 December, 2015. Results: MRI or Recheck CT brain post-operation can identify situations tumor. Conclusion: Tanscallosal a very important method.

Needle insertion is widely used in many clinical procedures such as biopsy, brachytherapy, and anesthesia. The success of these highly depends on accurate guidance the needle tip to a target area. Tissue deformation deflection are major factors that affect accuracy precision insertion. In this paper, new finite element model approach couples both tissue proposed based stick-slip theory. A method adapts mesh developed. interactive soft established performed MATLAB. amounts for homogeneous...